Research theme for competitive and other funds (6)：
2022 - 2025 新規メンケス病治療薬創製を目指した銅錯体の体内動態および薬効の検討
2020 - 2023 Elucidation of low-frequency Raman spectra and its application to precision control of drug manufacturing process
2018 - 2022 Pharmacokinetics and pharmaceutics investigation on copper complex to development an oral therapeutic agent for Menkes disease.
2017 - 2021 Highly sensitive and specific measurement of pharmaceutical cocrystals based on the low-frequency Raman spectroscopy
2014 - 2017 Exploring pharmaceutical cocrystals in nanogram order by using microscpic Raman spectroscopy
2010 - 2012 Characterization of drug penetration to the brain for preventing development of symptoms and progress of the aging disease
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Papers (126)：
Yoshihisa Yamamoto, Mizuho Kajita, Yutaro Hirose, Naoki Shimada, Toshiro Fukami, Tatsuo Koide. Pharmaceutical Evaluation of Levofloxacin Orally Disintegrating Tablet Formulation Using Low Frequency Raman Spectroscopy. Pharmaceutics. 2023. 15. 8. 2041-2041
Yoshihisa Yamamoto, Kosuke Ohgi, Yoshinori Onuki, Toshiro Fukami, Tatsuo Koide. Quality Evaluation of Humidified Magnesium Oxide Tablet Formulations with Respect to Disintegration Time Prolongation. Chemical & pharmaceutical bulletin. 2023. 71. 2. 165-174
Ryotaro Haku, Kazuhiko Takatori, Naoto Suzuki, Makoto Ono, Varin Titapiwatanakun, Toshiro Fukami. Exploration and characterization of a novel cocrystal hydrate consisting of captopril, an amino acid-derived drug. CrystEngComm. 2023. 25. 17. 2523-2533
Yoshihisa Yamamoto, Misaki Hata, Saki Tanaka, Nanami Haraguchi, Naoto Suzuki, Toshiro Fukami, Tatsuo Koide. [Evaluation of the Pharmaceutical Properties of Clobetasol Propionate Ointments and Base Stability of the Mixture with Heparinoid Oil Based Creams]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2022. 142. 4. 421-430
Motoki Inoue, Takumi Osada, Hiroshi Hisada, Tatsuo Koide, Toshiro Fukami, Anjan Roy, James Carriere. Quantitative Monitoring of Cocrystal Polymorphisms in Model Tablets Using Transmission Low-Frequency Raman Spectroscopy. Journal of Pharmaceutical Sciences. 2022
佐藤匠, 羽石一輝, 井上元基, 小出達夫, 深水啓朗. In situ real-time monitoring of liposome during its preparation process using Raman spectroscopy. 日本薬剤学会年会講演要旨集(CD-ROM). 2022. 37th
佐藤匠, 羽石一輝, 久田浩史, 井上元基, 小出達夫, 深水啓朗. Simultaneous in situ monitoring of membrane phase transition and drug release of liposomes using Raman spectroscopy. 日本薬学会年会要旨集(Web). 2022. 142nd
2014/06/20 - Publisher, Advanced Powder Technology, Elsevier 2013 Excellence in Peer Review Contribution as a peer reviewer thanked by Elsevier and the Editors of Advanced Powder Technology
2004/07/17 - APSTJ Global Education Seminar Presentation Award 2004
2001/03/22 - The Nagai Foundation Tokyo Graduate Student Scholarship
Association Membership(s) (6)：
Japan Society of Pharmaceutical Machinery and Engineering
, 日本薬剤学会
, 日本薬学会
, Society for Applied Spectroscopy
, The Society of Powder Technology, Japan
, 医薬品医療機器レギュラトリーサイエンス財団
