Rchr
J-GLOBAL ID：200901006325274790
Update date: Nov. 26, 2024
Kimura Tsuyoshi
キムラ ツヨシ | Kimura Tsuyoshi
Affiliation and department：
Job title：
Professor
Homepage URL (1)：
https://sites.google.com/toyo.jp/mbme2024
Research field (3)：
Biochemistry
, Biomaterials
, Biomedical engineering
Research keywords (9)：
Biomaterial
, Cancer Immunology
, Decellularized Tissue
, Tissue Engineering
, Cell Separation
, immunomodulatory materials
, Regenerative Medicin
, High Pressure
, Gene delivery
Research theme for competitive and other funds (17)：
- 2023 - 2028 Development and application of ECM information analysis using decellularized matrix and proteomics.
- 2022 - 2026 新規極性評価法によるマクロファージ分極と生体材料特性の相関解明
- 2021 - 2026 脱細胞化組織機能の解明によるDestination Useデバイス設計指針の獲得
- 2021 - 2024 プログラム細胞死細胞を原料とした新しい人工細胞外小胞の開発
- 2021 - 2023 ナノ医薬品で培ったナノの視点が拓く環境問題ナノプラスチックの生態影響理解への挑戦
- 2019 - 2022 細胞移動制御による免疫シフトマテリアルの開発
- 2016 - 2020 脱細胞化生体組織の規範とする人工生体組織(Tissueoid)の創製
- 2016 - 2019 Development of a device for capturing immune cells
- 2011 - 2015 Development of the technology for the entire tissue restoration using decellularized tissues
- 2012 - 2014 細胞機能イメージングを実現する多機能走査型バイオプローブ顕微鏡の開発
- 2011 - 2014 脱細胞化組織の高次機能複合化技術の開発
- 2010 - 2012 Establishment of novel living tissue adhesion method by using integrated low-level energies of heat, pressure and vibration
- 2008 - 2011 高圧凝縮核酸の物性解析および遺伝子制御への応用
- 2008 - 2011 Pressure controlling of DNA structure and transcription
- 2005 - 2007 ナノ無機・有機複合塩を用いた遺伝子送達システムの開発
- 2005 - 2007 Gene delivery using inorganic/organic nano-particles prepared by high pressurization
- 2004 - 2006 Gene delivery application of the polymer assembly interconnected by hydrogen bonding prepared by using ultra-high pressure
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Papers (202)：
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Sreypich Say, Mika Suzuki, Yoshihide Hashimoto, Tsuyoshi Kimura, Akio Kishida. Fibroblast and THP-1 Cell Response to Multi-Arm PEGNHS-Modified Decellularized Porcine Pericardium. IOCFB 2024. 2024. 3-3
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Hiroki Tsutsumi, Tomoki Chiba, Yuta Fujii, Takahide Matsushima, Tsuyoshi Kimura, Akinori Kanai, Akio Kishida, Yutaka Suzuki, Hiroshi Asahara. Single-nucleus transcriptional and chromatin accessibility analyses of maturing mouse Achilles tendon uncover the molecular landscape of tendon stem/progenitor cells. bioRxiv : the preprint server for biology. 2024
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Yoshihide Hashimoto, Jun Negishi, Seiichi Funamoto, Tsuyoshi Kimura, Hisatoshi Kobayashi, Tetsuro Oshika, Akio Kishida. Preparation, physico-biochemical characterization, and proteomic analysis of highly transparent corneal extracellular matrices for lamellar keratoplasty and tissue-engineered cornea construction. Materials Today Bio. 2024. 28. 101241-101241
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Mako Kobayashi, Jun Negishi, Naoki Ishida, Yoshihide Hashimoto, Yoshihiro Sasaki, Kazunari Akiyoshi, Tsuyoshi Kimura, Akio Kishida. Effects of the matrix-bounded nanovesicles of high-hydrostatic pressure decellularized tissues on neural regeneration. Science and Technology of Advanced Materials. 2024. 25. 1
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Sreypich Say, Mika Suzuki, Yoshihide Hashimoto, Tsuyoshi Kimura, Akio Kishida. Investigation of anti-adhesion ability of 8-arm PEGNHS-modified porcine pericardium. Biomedical Materials. 2024. 19. 3. 035012-035012
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MISC (97)：
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鈴木 美加, 木村 剛, 岡田 正弘, 松本 卓也, 山田 将博, 江草 宏, 中村 奈緒子, 岸田 晶夫. 歯根膜応用を目指した石灰化dECM膜のin vivo骨結合性評価. 日本歯科理工学会誌. 2023. 42. Special Issue81. 18-18
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中村奈緒子, 山本琉加, 小暮一輝, 木村剛, 岸田晶夫. 脱細胞化歯肉を用いた角化歯肉の再構築. 日本再生医療学会総会(Web). 2023. 22nd
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中村奈緒子, 中村奈緒子, 樋口亮平, 木村剛. 細胞周期を考慮したマクロファージ表現型の画像分類. 日本生体医工学会大会プログラム・抄録集(Web). 2023. 62nd
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木村剛, 石垣瑠梨, 梁枕, 萩原萌子, 橋本良秀, 岸田晶夫, 野村渉, 中村奈緒子. Evaluation of biomaterials using luminescent peptide-knock-in macrophages. 生体医歯工学共同研究拠点成果報告会. 2023. 2022 (CD-ROM)
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鈴木美加, 木村剛, 橋本良秀, 岸田晶夫, 高橋宏信, 清水達也, 岡田正弘, 松本卓也, 中村奈緒子. Evaluation of bone affinity of mineralized decellularized tissue as application of hard-soft tissue. 生体医歯工学共同研究拠点成果報告会. 2023. 2022 (CD-ROM)
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Education (2)：
- 1997 - 1999 Kyoto Institute of Technology Graduate School of Science and Technology
- 1993 - 1997 Kyoto Institute of Technology
Professional career (1)：
- Ph.D (Kyoto Institute of Technology)
Work history (4)：
- 2024/04 - 現在 Toyo University Department of Biomedical Engineering, Faculty of Life Sciences Professor
- 2013/04 - 2024/03 Tokyo Medical and Dental University Institute of Biomaterials and Bioengineering
- 2004/10 - 2013/03 Tokyo Medical and Dental University Institute of Biomaterials and Bioengineering
- 2003/04 - 2004/09 National Cerebral and Cardiovascular Center, Research Institute Department of Biomedical Engineering
Awards (9)：
- 2019/10 - 日本歯科理工学会 企業賞(ジーシー賞) PEEK表面のハイドロキシアパタイト修飾
- 2019/01 - 未踏科学技術協会インテリジェント・ナノ材料研究会 髙木賞 脱細胞化生体組織を基盤とする階層・異方性組織の構築
- 2018/01 - 東京医科歯科大学生体材料工学研究所 平成30年度生体材料工学研究所医歯科学研究助成
- 2017/02 - Presentation Award
- 2016/11 - The Japanese Society for Biomaterials 2016 Journal of Materials Chemistry B Presentation Prize
- 2015/11 - Japanese Society of Artificial Organs 2015年度 Yoshimi Memorial T.M.P Grant
- 2010/11 - Japanese Society of Artificial Organ 2020 Paper Award Study on the physical properties of tissue-engineered blood vessels made by chemical cross-linking and polymer-tissue cross-linking
- 2008/11 - Japanese Society of Artificial Organs 2008 Paper Award Preparation of poly(vinyl alcohol)/DNA hydrogels via hydrogen bonds formed on ultra-high pressurization and controlled release of DNA from the hydrogels for genedelivery.
- 2005/11 - 日本人工臓器学会 2005年度日本人工臓器学会論文賞
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Association Membership(s) (7)：
THE SOCIETY OF LIFE SUPPORT ENGINEERING
, 日本人工臓器学会
, 日本再生医療学会
, 日本バイオマテリアル学会
, 高分子学会
, 日本炎症・再生医学会
, 日本生体医工学会
