Hirashima Naohide

ヒラシマナオヒデ | Hirashima Naohide

Affiliation and department：
Other affiliations (1)：

名古屋市立大学創薬基盤科学研究所教授

Homepage URL (1)： https://www.nagoya-cu.ac.jp/phar/grad/soyaku/seimei/chobunshi/

Research field (5)： Nano/micro-systems , Nanobioscience , Pharmaceuticals - analytical and physicochemistry , Cell biology , Biophysics

Research keywords (6)：可視化解析 , 人工細胞 , 分泌 , マスト細胞 , エクソサイトーシス , アレルギー

Research theme for competitive and other funds (45)：

2020 - 2023 Construction of basophil/liposome hybrid secretory system and its application to cell therapy and DDS.
2019 - 2022 マスト細胞における分泌顆粒の『不均質性』とアレルギー応答の『多様性』に関する研究
2018 - 2021 A novel calcium store and Ca2+ release in secretory cells
2018 - 2021 分泌細胞における新しいカルシウムストアとCa2+放出の誘導機構
2016 - 2019 The allergen affinity-based molecular editing of the high-affinity receptor for IgE on allergic responses.

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Papers (139)：

Hikaru Teramoto, Naohide Hirashima, Masahiko Tanaka. A Simple Method for Purified Primary Culture of Enteric Glial Cells from Mouse Small Intestine. Biological and Pharmaceutical Bulletin. 2022. 45. 4. 547-551
Horie Y, Arame T, Hirashima N, Tanaka M. Promotion of dendritic differentiation of cerebellar Purkinje cells by Ca2+/calmodulin-dependent protein kinase IIα, IIβ and IV and possible involvement of CREB phosphorylation. Neuroscience 458, 87-98 (2021). 2021. 458. 87-98
Ruriko Suzuki, Yoshikazu Inoh, Satoru Yokawa, Tadahide Furuno, Naohide Hirashima. Receptor dynamics regulates actin polymerization state through phosphorylation of cofilin in mast cells. Biochemical and biophysical research communications. 2021. 534. 714-719
U Okura, N Hirashima, M Tanaka. Calcineurin B1 deficiency in glial cells reduces gastrointestinal motility and results in maldigestion and/or malabsorption in mice. Biol. Pharm. Bull. 2019. 42. 7. 1230-1235
Suzuki R, Inoh Y, Yokawa S, Furuno T, Hirashima N. Monomer hapten and hapten-specific IgG inhibit mast cell activation evoked by multivalent hapten with different mechanisms. European Journal of Immunology. 2019. 49. 2172-2183

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MISC (59)：

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Books (6)：

薬学生の物理化学
培風館 2021 ISBN:9784563085681
物理系薬学III
東京化学同人 2016
薬学生のための基礎シリーズ7 基礎化学
培風館 2014 ISBN:9784563085575
免疫学辞典
東京化学同人 2001
医学&サイエンスシリーズ細胞内シグナル伝達がわかる
羊土社 2000

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Education (3)：

1986 - 1996 東京大学大学院薬学系研究科博士後期課程
1984 - 1986 東京大学大学院薬学系研究科博士前期課程
1980 - 1984 The University of Tokyo Faculty of Pharmaceutical Sciences

Work history (5)：

2006/04 - 現在 Nagoya City University Graduate School of Pharmaceutical Sciences, Department of Cellular Biophysics
2013/04 - 2017/03 Nagoya City University Graduate School of Pharmaceutical Sciences
1998/01 - 2006/03 Nagoya City University Medicin
1994/08 - 1998/12 The University of Tokyo Faculty of Pharmaceutical Sciences
1986/10 - 1994/07 Kyushu University School of Pharmaceutical Sciences

Awards (1)：

2000/03 - 日本薬学会日本薬学会奨励賞神経・免疫系におけるエクソサイトーシスの分子機構

Association Membership(s) (7)：

The American Society for Cell Biology , JAPANESE SOCIETY OF ALLERGOLOGY , BIOIMAGING SOCIETY , THE JAPANESE BIOCHEMICAL SOCIETY , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE BIOPHYSICAL SOCIETY OF JAPAN , THE PHARMACEUTICAL SOCIETY OF JAPAN

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