Research field (5):
Pharmaceuticals - chemistry and drug development
, Biochemistry
, Molecular biochemistry
, Environmental effects of chemicals
, Environmental effects of radiation
Research keywords (11):
radiation hormesis
, 核酸化学
, ビタミン
, 点突然変異
, DNA修復
, 光化学
, DNA酸化損傷
, point mutation
, DNA repair
, Photochemistry
, DNA oxidative damage
Research theme for competitive and other funds (11):
2011 - 2015 Study on the oxazolone-oxazolone cluster damage
2013 - 転写因子NF-κB-DNA結合阻害剤の探索
2012 - γ線照射により生成するG→Cトランスバージョン誘因酸化損傷の検出
2011 - 皮膚の老化に関わるグアニン酸化損傷の基礎研究
2011 - 生涯学習講座に適した化学実験の題材探し
2007 - 2009 Detection of guanine oxidation products which cause G→C transversions.
2007 - G:C→C:G点突然変異を防ぐ酵素の探索
2005 - 2006 真核生物DNAポリメラーゼα、δ、εによるG→Cトランスバージョンの可能性
1999 - 2001 DNA酸化生成物、イミダゾロンによる突然変異の発生機構とその修復機構の解明
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Papers (71):
Katsuhito Kino. Calculations of the Radiation Dose for the Maximum Hormesis Effect. Radiation. 2024. 4. 1. 69-84
Taishu Kawada, Moka Maehara, Katsuhito Kino. Increased Yields of the Guanine Oxidative Damage Product Imidazolone Following Exposure to LED Light. Reactions. 2023. 4. 4. 801-810
Kawata Taishu, Masayo Hirao-Suzuki, Masayuki Morikawa, Katsuhito Kino. DNA damages and mutations・ the new theory of low dose exposure. BIO Clinica. 2023. 38. 9. 41-43
Katsuhito Kino. The Radiation-Specific Components Generated in the Second Step of Sequential Reactions Have a Mountain-Shaped Function. Toxics. 2023. 11. 4. 301-301
Kawada, T, Kino, K, Matsuzawa, Y, Morikawa, M, Okamoto, Y, Kobayashi, T, Tanaka, Y. N′1,N′4-bis(2-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)ethylidene)succinohydrazide. Molbank. 2022. 2022. 2022. M1436-M1436
Suzuki Masayo, Kawada Taishu, Oyoshi Takanori, Kobayashi Takanobu, Miyazawa Hiroshi, Kino Katsuhito. P-007 The influence of contiguous oxazolone on DNA synthesis(Poster Sessions). 2015. 44. 96-96
Suzuki Masayo, Kawada Taishu, Morikawa Masayuki, Kobayashi Takanobu, Miyazawa Hiroshi, Kino Katsuhito. P-081 Translesion synthesis past an oxidatively damaged guanine by REV1 and DNA polymerase ζ(Poster Sessions). 2014. 43. 131-131