Rchr
J-GLOBAL ID:200901006999475325
Update date: Oct. 01, 2024
Niida Hiroyuki
ニイダ ヒロユキ | Niida Hiroyuki
Affiliation and department:
Job title:
Lecturer
Research field (1):
Molecular biology
Research keywords (6):
DNA修復
, チェックポイント
, 細胞周期
, DNA repair
, checkpoint
, cell cycle
Research theme for competitive and other funds (16):
- 2024 - 2028 ICI感受性に関与するヌクレオチド除去修復機構の解明とその医学応用
- 2021 - 2023 Molecular mechanisms of development of malignant female cancers associated with X-chromosome reactivation
- 2020 - 2023 先天性角化異常症細胞のゲノム不安定性を招く新規ヌクレオチド除去修復因子の欠損
- 2020 - 2023 複製ストレス応答における癌抑制因子の新機能と染色体不安定化の抑制機構の解明
- 2016 - 2019 S期特異的な複製共役ヌクレオチド除去修復機構についての解析 研究課題
- 2016 - 2018 Regulatory mechanism of homologous recombination in a Sex-chromosome-dependent manner
- 2013 - 2017 Molecular mechanisms of crosstalk between DNA-damage response and signal transduction
- 2014 - 2016 Long non-coding RNA associated with cancer stemness
- 2012 - 2016 DNA複製開始制御における新規機構の解析 研究課題
- 2011 - 2013 DNA複製に伴うチェックポイント因子とdNTPs供給の時空間的クロストーク
- 2009 - 2011 DNA修復時に働くRNRの活性調節機構の解析 研究課題
- 2008 - 2009 チェックポイントキナーゼによる晩発型個体発ガン抑制機構の解明
- 2007 - 2008 哺乳動物細胞のDNA修復時にdNTPs供給を担保するRNR制御機構の解析 研究課題
- 2005 - 2006 Molecular Mechanism of Mitotic Catastrophe
- 2001 - 2005 Regulation of cell cycle checkpoints that monitor DNA damage and DNA replication block.
- DNA repair
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Papers (58):
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Takahito Suzuki, Satoshi Sakai, Kosuke Ota, Mika Yoshida, Chiharu Uchida, Hiroyuki Niida, Takafumi Suda, Masatoshi Kitagawa, Tatsuya Ohhata. Expression of Tumor Suppressor FHIT Is Regulated by the LINC00173-SNAIL Axis in Human Lung Adenocarcinoma. International journal of molecular sciences. 2023. 24. 23
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Maya Suzuki, Satoshi Sakai, Kosuke Ota, Yuki Bando, Chiharu Uchida, Hiroyuki Niida, Masatoshi Kitagawa, Tatsuya Ohhata. CCIVR2 facilitates comprehensive identification of both overlapping and non-overlapping antisense transcripts within specified regions. Scientific reports. 2023. 13. 1. 14807-14807
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Chiharu Uchida, Hiroyuki Niida, Satoshi Sakai, Kenta Iijima, Kyoko Kitagawa, Tatsuya Ohhata, Bunsyo Shiotani, Masatoshi Kitagawa. p130RB2 positively contributes to ATR activation in response to replication stress via the RPA32-ETAA1 axis. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2023. 1870. 6. 119484-119484
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Sanghyun Sung, Eunkyeong Kim, Hiroyuki Niida, Chuna Kim, Junho Lee. Distinct characteristics of two types of alternative lengthening of telomeres in mouse embryonic stem cells. Nucleic acids research. 2023
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Kosuke Ota, Satoshi Sakai, Tatsuya Ohhata, Takahito Suzuki, Chiharu Uchida, Hiroyuki Niida, Masatoshi Kitagawa. APOBEC3B expression is promoted by lincNMR collaborating with TGF-β-Smad pathway. Carcinogenesis. 2022. 44. 1. 1-14
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MISC (7):
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Hiroyuki Niida. Role of histone modification enzymes for promoting nucleotide excision repair. 2020. 274. 12. 1175-1180
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Tatsuya Ohhata, Mika Matsumoto, Martin Leeb, Shinwa Shibata, Kyoko Kitagawa, Hiroyuki Niida, Masatoshi Kitagawa, Anton Wutz. Molecular dissection of Xist repression mechanisms in mouse ES cells. GENES & GENETIC SYSTEMS. 2014. 89. 6. 308-308
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原田 雅教, 神武 洋二郎, 北川 恭子, 丹伊田 浩行, 椙村 春彦, 北川 雅敏. 非小細胞肺癌においてY-box binding protein 1(YB-1)はサイクリンD1に直接結合し転写活性を亢進させる(YB-1 binds to and activates cyclinD1 transcriptional activities in Non-Small-Cell Lung Cancer). 日本癌学会総会記事. 2014. 73回. P-3092
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M. Harada, Y. Kotake, T. Ohhata, K. Kitagawa, H. Niida, S. Matsuura, K. Funai, H. Sugimura, T. Suda, M. Kitagawa. Yb-1 Promotes Transcription Of Cyclin D1 In Human Non-Small-Cell Lung Cancers. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2014. 189
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NIIDA Hiroyuki, SHIMADA Midori, MURAKAMI Hiroshi, NAKANISHI Makoto. Mechanisms of dNTP supply that play an essential role in maintaining genome integrity in eukaryotic cells. 2010. 101. 12. 2505-2509
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Education (2):
- 1989 - 1991 Obihiro University of Agriculture and Veterinary Medicine
- 1984 - 1988 Obihiro University of Agriculture and Veterinary Medicine Faculty of Animal Husbandry
Professional career (2):
- (BLANK) (Yamagata University)
- (BLANK) (Obihiro University of Agriculture and Veterinary Medicine)
Work history (7):
Awards (1):
- 2004 - 平成14年度名古屋桜仁会医学研究奨励賞
Association Membership(s) (4):
日本放射線影響学会
, 日本癌学会
, 分子生物学会
, 生化学会
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