Research keywords (7)：
Solid Extraction Metabolomics
, High-Performance Liquid Chromatography
, Gas Chromatography
, Mass Spectrometry
, Forensic Toxicology
, Analytical Chemistry
, Legal Medicine
Research theme for competitive and other funds (24)：
2015 - 現在 最新質量分析計による体液中危険ドラッグの検出・同定法の開発及び学際的検討
2012 - 現在 バイオマーカーとしての胆汁酸の法医学的応用
2023 - 2026 Elusidation for Toxicity Mechanism of Synthetic Cannabinoids by Multi-omics Approach: Focusing on Cardiovascular System
2019 - 2023 分解後プロテオミクス:法医学からの新規プロテオミクス
2019 - 2023 高感度新規胆汁酸分析法を用いたNASH肝線維化に関わる胆汁酸種の解明
2018 - 2021 Accurate measurement of natural toxins in body fluids using deuterated standards and search of specific markers for the rapid diagnosis
2015 - 2018 New prevention strategies for non-alcoholic steatohepatitis - a study on the importance of blood pressure and nutritional management
2015 - 2018 Metabolic profiling analysis of rat administered natural toxins
2013 - 2016 A study to clarify the mechanism of non-alcoholic steatohepatitis using 3 different strains of rats fed with high fat and cholesterol diet
2011 - 2015 新しいフーリエ変換ーリニアイオントラップ質量分析計の法医学への応用
2011 - 2014 Molecular mechanism for prevention of high-fat and -cholesterol-induced fibrotic steatohepatitis and development of the non-invasive biomarker
2006 - 2010 ナノスケール高速液体クロマトグラフィー/質量分析計の法医学への応用
2005 - 2007 固相マイクロ抽出法による新規乱用薬物のスクリーーニング分析
2003 - 2006 薬毒物の作用機序の解析に有用な新しい質量分析法
2002 - 2006 Application of high-performance liquid chromatography/laser spray mass spectrometry to legal medicine
2001 - 2004 Rapid screening of inorganic poisons by column-switching ion chromatography
2000 - 2002 Sensitive analysis for drugs-of-abuse in human body fluids by GC/MS/MS
1999 - 2002 New approach for drug monitoring by using human sweat secreted
1999 - 2001 Establishment of forensic molecular genetic analyzing method using the rapid detection allele-specific MVR-PCR
1998 - 2000 HPLC/タンデムMSによるドーピング薬物の迅速高感度検出法の確立
1997 - 2000 Development of surface ionization organic mass spectrometer (SIOMS) for the application to forensic toxicology
1996 - 1997 Molecular mechanism of alcoholism : Ethanol and cell signaling
1996 - 1997 マイクロ固相抽出(SPME)法による体液中乱用薬物の高感度検出法
1994 - 1995 トリカブト毒成分(アコニチン)HPLC/MSによる高感度分析
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Papers (55)：
Yujin Natori, Takashi Yoshimoto, Toshimichi Yamamoto, Akira Ishii. Identification and quantification of diphenhydramine, haloperidol, and its metabolite, reduced haloperidol in a saponified brain specimen that was immersed in the sea water for more than 10 years. Legal medicine (Tokyo, Japan). 2023. 61. 102188-102188
Tomomi Ohara, Takashi Yoshimoto, Yujin Natori, Akira Ishii. A simple method for the determination of glyphosate, glufosinate and their metabolites in biological specimen by liquid chromatography/tandem mass spectrometry: an application for forensic toxicology. Nagoya journal of medical science. 2021. 83. 3. 567-587
Tomomi Asano, Kentaro Taki, Kazuya Kitamori, Hisao Naito, Tamie Nakajima, Hitoshi Tsuchihashi, Akira Ishii, Kei Zaitsu. One-Pot Extraction and Quantification Method for Bile Acids in the Rat Liver by Capillary Liquid Chromatography Tandem Mass Spectrometry. ACS omega. 2021. 6. 12. 8588-8597
Kazuaki Hisatsune, Tasuku Murata, Koretsugu Ogata, Minemasa Hida, Akira Ishii, Hitoshi Tsuchihashi, Yumi Hayashi, Kei Zaitsu. RECiQ: A Rapid and Easy Method for Determining Cyanide Intoxication by Cyanide and 2-Aminothiazoline-4-carboxylic Acid Quantification in the Human Blood Using Probe Electrospray Ionization Tandem Mass Spectrometry. ACS omega. 2020. 5. 36. 23351-23357
Section 8-2-04. Surface Ionization and its application to GC-MS
Elsevier Science Ltd. 2006 ISBN:9780080438474
II.7.7. Diazine and triazne herbicides. Drugs and Poisons in Humans. A Hadnbook of Practical Analysis (eds. Suzuki O. and Watanabe K.)
Springer-Verlag, Berlin Heidelberg 2005
II.3.1. Phenothiaznes. Drugs and Poisons in Humans. A Hadnbook of Practical Analysis (eds. Suzuki O. and Watanabe K.)
Springer-Verlag, Berlin Heidelberg 2005
II.2.8. Phencyclidine. Drugs and Poisons in Humans. A Hadnbook of Practical Analysis (eds. Suzuki O. and Watanabe K.)
Springer-Verlag, Berlin Heidelberg 2005
