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J-GLOBAL ID:200901007303692129   Update date: May. 27, 2020

Tanimoto Keiji

タニモト ケイジ | Tanimoto Keiji
Research field  (2): Surgical dentistry ,  Medical biochemistry
Research keywords  (6): Pharmacogenetics ,  individualized therapy ,  hypoxia ,  Transcription ,  HIF-1 ,  transcription
Research theme for competitive and other funds  (4):
  • 2011 - 2013 The roles of HIF-DEC pathway on DNA repair systems in hypoxic oral cancer cells.
  • 2009 - 2011 Identification of EMP3 as a tumor suppressor gene for esophageal squamous cell carcinoma and elucidation of its regulation mechanism.
  • 2003 - 2004 Mechanisms of inhibitory effect on hypoxia-inducible transcriptional activities.
  • 2001 - 2002 Molecular diagnosis and therapy based on mechanisms of the regulation of hypoxia-inducible
Papers (74):
  • Shimamoto K, Tanimoto K, Fukazawa T, Nakamura H, Kanai A, Bono H, Ono H, Eguchi H, Hirohashi N. GLIS1, a novel hypoxia-inducible transcription factor, promotes breast cancer cell motility via activation of WNT5A. Carcinogenesis. 2020. bgaa010
  • Fukazawa T, Tanimoto K, Shrestha L, Imura T, Takahashi S, Sueda T, Hirohashi N, Hiyama E, Yuge L. Simulated microgravity enhances CDDP-induced apoptosis signal via p53-independent mechanisms in cancer cells. PloS one. 2019. 14. 7. e0219363
  • Nakamura, Hideaki, Bono, Hidemasa, Hiyama, Keiko, Kawamoto, Takeshi, Kato, Yukio, Nakanishi, Takeshi, Nishiyama, Masahiko, Hiyama, Eiso, Hirohashi, Nobuyuki, Sueoka, Eisaburo, Poellinger, Lorenz, Tanimoto, Keiji. Differentiated embryo chondrocyte plays a crucial role in DNA damage response via transcriptional regulation under hypoxic conditions. PLOS ONE. 2018. 13. 2
  • Morita, Akinori, Takahashi, Ippei, Sasatani, Megumi, Aoki, Shin, Wang, Bing, Ariyasu, Shinya, Tanaka, Kaoru, Yamaguchi, Tetsuji, Sawa, Akiko, Nishi, Yurie, Teraoka, Tatsuro, Ujita, Shohei, Kawate, Yosuke, Yanagawa, Chihiro, Tanimoto, Keiji, Enomoto, Atsushi, Nenoi, Mitsuru, Kamiya, Kenji, Nagata, Yasushi, Hosoi, Yoshio, Inaba, Toshiya. A Chemical Modulator of p53 Transactivation that Acts as a Radioprotective Agonist. MOLECULAR CANCER THERAPEUTICS. 2018. 17. 2. 432-442
  • Furukawa T, Tanimoto K, Fukazawa T, Imura T, Kawahara Y, Yuge L. Simulated microgravity attenuates myogenic differentiation via epigenetic regulations. NPJ microgravity. 2018. 4. 11
more...
MISC (9):
  • 深澤 賢宏, 谷本 圭司, 山岡 絵美, 金輪 真佐美, 廣橋 伸之, 檜山 英三. 小児肝がんにおいて高発現する膜蛋白ADAM32の分子機能および治療標的としての検討. 日本癌治療学会学術集会抄録集. 2018. 56回. P111-4
  • 深澤 賢宏, 谷本 圭司, 山岡 絵美, 金輪 真佐美, 廣橋 伸之, 檜山 英三. 小児肝がん細胞において高発現する膜蛋白ADAM32の意義. 生命科学系学会合同年次大会. 2017. 2017年度. [1P-0958]
  • 和田 智, 江口 英孝, 坊農 秀雅, 二宮 裕一, 岩佐 泰靖, 谷本 圭司, 檜山 桂子, 岡崎 康司, 西山 正彦. SFRS10 as an immortalization-associated gene in cancer cells: The functional network and roles in alternative splicing. 日本癌学会総会記事. 2008. 67回. 405-405
  • 阿部 恵子, 高橋 貞夫, 谷本 圭司, 石田 万里, 桑羽 賀子, 沢野 真理子, 有広 光司, 茶山 一彰, 吉栖 正生, 石田 隆史. ヒトマクロファージ及び血管平滑筋細胞における超低比重リポ蛋白質受容体発現の低酸素によるHIF-1依存性機構を介した誘導(Hypoxia Induces the Expression of Very Low-Density Lipoprotein Receptor in Human Macrophages and Vascular Smooth Muscle Cells via a HIF-1 Dependent Mechanism). 日本動脈硬化学会総会プログラム・抄録集. 2007. 39回. 227-227
  • 麓 祥一, 下國 達志, 谷本 圭司, 檜山 桂子, 野口 剛, 川原 克信, 姜 貴嗣, 嶋田 裕, 岡崎 康司, 大谷 敬子, 大瀧 慈, 檜山 英三, 西山 正彦. 食道癌における抗癌剤新規効果規定因子の同定及び機能解析. 日本外科学会雑誌. 2006. 107. 臨増2. 678-678
more...
Education (2):
  • 1994 - 1998 Hiroshima University Graduate School, Division of Dental Research
  • 1988 - 1994 Hiroshima University Faculty of Dentistry
Work history (6):
  • 2007/04/01 - Hiroshima University
  • 2002/04/01 - 2007/03/31 Hiroshima University
  • 2001/04/01 - 2002/03/31 Hiroshima University
  • 2000/01/01 - 2001/03/31 Japan Society for the Promotion of Science research fellow
  • 1998/07/01 - 1999/12/31 Cell and Molecular Biology guest researcher
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Association Membership(s) (2):
The Japanese Pharmacological Society ,  American Association for Cancer Research
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