Rchr
J-GLOBAL ID:200901007303692129   Update date: Apr. 12, 2021

Tanimoto Keiji

タニモト ケイジ | Tanimoto Keiji
Affiliation and department:
Research field  (2): Surgical dentistry ,  Medical biochemistry
Research keywords  (6): Pharmacogenetics ,  individualized therapy ,  hypoxia ,  Transcription ,  HIF-1 ,  transcription
Research theme for competitive and other funds  (12):
  • 2017 - 2019 トリプルネガティブ乳がん細胞に対するレスベラトロールによる新規治療・予防法の開発
  • 2015 - 2017 新規低酸素誘導性初期化遺伝子GLIS1機能解析および診断・治療法開発研究
  • 2015 - 口腔扁平上皮癌の悪性度を規定する転写因子DEC-Twist分子制御機構の解明
  • 2011 - 2013 The roles of HIF-DEC pathway on DNA repair systems in hypoxic oral cancer cells.
  • 2009 - 2011 Identification of EMP3 as a tumor suppressor gene for esophageal squamous cell carcinoma and elucidation of its regulation mechanism.
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Papers (89):
  • Shimamoto K, Tanimoto K, Fukazawa T, Nakamura H, Kanai A, Bono H, Ono H, Eguchi H, Hirohashi N. GLIS1, a novel hypoxia-inducible transcription factor, promotes breast cancer cell motility via activation of WNT5A. Carcinogenesis. 2020. bgaa010
  • Takahiro Fukazawa, Keiji Tanimoto, Looniva Shrestha, Takeshi Imura, Shinya Takahashi, Taijiro Sueda, Nobuyuki Hirohashi, Eiso Hiyama, Louis Yuge. Simulated microgravity enhances CDDP-induced apoptosis signal via p53-independent mechanisms in cancer cells. PloS one. 2019. 14. 7. e0219363
  • Akinori Morita, Ippei Takahashi, Megumi Sasatani, Shin Aoki, Bing Wang, Shinya Ariyasu, Kaoru Tanaka, Tetsuji Yamaguchi, Akiko Sawa, Yurie Nishi, et al. A chemical modulator of p53 transactivation that acts as a radioprotective agonist. Molecular Cancer Therapeutics. 2018. 17. 2. 432-442
  • Furukawa T, Tanimoto K, Fukazawa T, Imura T, Kawahara Y, Yuge L. Simulated microgravity attenuates myogenic differentiation via epigenetic regulations. NPJ microgravity. 2018. 4. 11
  • Hideaki Nakamura, Hidemasa Bono, Keiko Hiyama, Takeshi Kawamoto, Yukio Kato, Takeshi Nakanishi, Masahiko Nishiyama, Eiso Hiyama, Nobuyuki Hirohashi, Eisaburo Sueoka, et al. Differentiated embryo chondrocyte plays a crucial role in DNA damage response via transcriptional regulation under hypoxic conditions. PloS one. 2018. 13. 2. e0192136
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MISC (24):
Education (3):
  • 1994 - 1998 Hiroshima University Graduate School, Division of Dental Research
  • 1988 - 1994 Hiroshima University Faculty of Dentistry
  • 1988 - 1994 Hiroshima University
Work history (7):
  • 2007/04/01 - 2020/03/31 Hiroshima University Research Institute for Radiation Biology and Medicine Assistant Professor
  • 2002/04/01 - 2007/03/31 Hiroshima University Research Institute for Radiation Biology and Medicine
  • 2001/04/01 - 2007/03/31 Hiroshima University Research Institute for Radiation Biology and Medicine Research Associate
  • 2001/04/01 - 2002/03/31 Hiroshima University Research Institute for Radiation Biology and Medicine
  • 2000/01/01 - 2001/03/31 Japan Society for the Promotion of Science research fellow
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Association Membership(s) (11):
The Japanese Pharmacological Society ,  日本癌治療学会 ,  日本癌学会 ,  日本歯科基礎医学会 ,  日本抗加齢医学会 ,  日本口腔外科学会 ,  日本分子生物学会 ,  放射線影響学会 ,  がん分子標的治療学会 ,  がんとハイポキシア研究会 ,  American Association for Cancer Research
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