sakuta Hiraki

Affiliation and department：
Homepage URL (1)： https://www.nibb.ac.jp/~transgen/

Research field (2)： Neuroscience - general , Developmental biology

Research keywords (3)：体液恒常性 , マウス , 網膜神経節細胞サブタイプ

Research theme for competitive and other funds (10)：

2021 - 2024 水分摂取行動制御のための浸透圧感知の脳内機構
2018 - 2021 Central mechanisms of sodium sensing for water-intake control
2012 - 2017 Study of brain mechanisms controlling body-fluid homeostasis
2011 - 2013 方向選択性網膜神経節細胞の方向選択性決定機構
2008 - 2010 Molecular mechanisms for regional specification in the retina

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Papers (24)：

Hiraki Sakuta, Chia-Hao Lin, Takeshi Y Hiyama, Takashi Matsuda, Katsushi Yamaguchi, Shuji Shigenobu, Kenta Kobayashi, Masaharu Noda. SLC9A4 in the organum vasculosum of the lamina terminalis is a [Na+] sensor for the control of water intake. Pflugers Archiv : European journal of physiology. 2020
Hiraki Sakuta. Nax-positive glial cells in the organum vasculosum laminae terminalis produce epoxyeicosatrienoic acids to induce water intake in response to increases in [Na+] in body fluids. Neuroscience Research. 2020. 154. 45-51
Beerend H.J. Winkelman, Marcus H. Howlett, Maj-Britt Holzel, Coen Joling, Kathryn H. Fransen, Gobinda Pangeni, Sander Kamermans, Hiraki Sakuta, Masaharu Noda, Huibert J. Simonsz, et al. Nystagmus in patients with congenital stationary night blindness (CSNB) originates from synchronously firing direction-selective retinal ganglion cells. 2019
Kengo Nomura, Takeshi Y. Hiyama, Hiraki Sakuta, Takashi Matsuda, Chia-Hao Lin, Kenta Kobayashi, Kazuto Kobayashi, Tomoyuki Kuwaki, Kunihiko Takahashi, Shigeyuki Matsui, et al. [Na+] Increases in Body Fluids Sensed by Central Nax Induce Sympathetically Mediated Blood Pressure Elevations via H+-Dependent Activation of ASIC1a. Neuron. 2019. 101. 1. 60-75.e6
Hiraki Sakuta, Eri Nishihara, Takeshi Y. Hiyama, Chia-Hao Lin, Masaharu Noda. Na-x signaling evoked by an increase in [Na+] in CSF induces water intake via EET-mediated TRPV4 activation. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 2016. 311. 2. R299-R306

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MISC (9)：

Masaharu Noda, Hiraki Sakuta. Central regulation of body-fluid homeostasis. Trends in Neurosciences. 2013. 36. 11. 661-673
Hiraki Sakuta, Ryoko Suzuki, Masaharu Noda. Retroviral Vector-Mediated Gene Transfer into the Chick Optic Vesicle by In Ovo Electroporation. Electroporation and Sonoporation in Developmental Biology. 2009. 105-116
Hiraki Sakuta, Ryoko Suzuki, Masaharu Noda. Retrovirus vector-mediated gene transfer into the chick optic vesicle byin ovoelectroporation. Development, Growth & Differentiation. 2008. 50. 6. 453-457
Takafumi Shintani, Hiraki Sakuta, Masaharu Noda. Molecular mechanisms for the formation of topographic retinotectal projection. Brain and Nerve. 2008. 60. 4. 425-435
新谷隆史, 作田拓, 野田昌晴. Molecular mechanisms for the formation of topographic retinotectal projection. Brain and nerve. 2008. 60. 4. 425-435

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Professional career (1)：

博士(理学) (京都大学)

Work history (5)：

2022/04 - 現在 National Institute for Basic Biology Trans-Scale Biology Center, Model Organisms Facility
2019/04 - 2022/03 National Institute for Basic Biology
2007/04 - 2019/03 National Institute for Basic Biology
2004/04 - 2007/03 National Institute for Basic Biology
2001/10 - 2004/03 National Institute for Basic Biology

Association Membership(s) (1)：

日本神経科学会会

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