Rchr
J-GLOBAL ID:200901007987987203
Update date: Oct. 01, 2024
Harayama Hiroshi
ハラヤマ ヒロシ | Harayama Hiroshi
Affiliation and department:
Job title:
Professor
Research field (1):
Animal production science
Research keywords (4):
細胞内シグナリング
, Intracellular signaling
, Sperm
, Reproduction
Research theme for competitive and other funds (20):
- 2022 - 2025 Establishment and spread of the new assay for sperm flagellar function to improve artificial insemination results in the cattle
- 2021 - 2025 Studies on expressions and roles of INSL3 secretory dynamics and its receptor expression in reproductive organs and germ cells in female cattle
- 2020 - 2024 融合因子SOFの機能解析を通した精子-卵子の細胞膜融合機構の解明
- 2019 - 2021 Analyses of 3-dimensional rotation for the purpose of reconsidering criteria for the evaluation of flagellar functions in bull sperm
- 2017 - 2020 Studies on the mechanisms that cholesterol exerts its therapeutic effects on boar spermatozoa affected with summer infertility
- 2016 - 2019 Characterization and utilization of SPACA1 proteins for the purpose of establishment of a new method to predict freezability of bull sperm before cryopreservation
- 2014 - 2017 Etiology of boar spermatozoa affected with summer infertility in an attempt to develop a novel therapy
- 2013 - 2016 Expression of claudin family proteins in preimplantation embryos in the pig
- 2013 - 2016 Development of methods to evaluate molecular characteristics of livestock spermatozoa by the detection of aberrant fertility-regulating factors
- 2011 - 2012 Enhancement of the tolerance to the storage in boar and mouse spermatozoa by the re-maturation in vitro
- 2009 - 2011 Development of clinical therapeutic methods against failure of fertilizing functions causing summer infertility in boars
- 2008 - 2010 Targeted therapy for defect of fertilizing ability in the spermatozoa from subfertile livestock
- 2006 - 2007 An invention of method to predict reproductive performance of Japanese Black cattle by the evaluation of sperm ability to exhibit flagellar hyperactivation
- 2004 - 2005 An invention of method to suppress expression of sperm fertilizing ability for the purpose of establishment of production system of porcine embryos
- 1999 - 2001 Changes and functions of Anti-Agglutinin in boar spermatozoa during their capacitation
- 1999 - 2000 ブタ精子のキャパシテーション過程での頭部間凝集に及ぼすカルシウムの影響
- 1997 - 1999 ブタ活性化卵子の初期発生能ならびに単為発生胚の初期胚特異タンパク質の発現性
- 1997 - 1999 Studies on production of pig embryos from growing oocytes
- 1997 - 1998 Anti-Agglutinin出現機序の生化学的および免疫組織学的解析
- 1996 - 1996 精巣上体液中の精子頭部間凝集抑制タンパク質を修飾する糖鎖の特性解析
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Papers (83):
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MIYAMOTO Natsuko, OHYA Akihiro, DURITAHALA, SAKASE Mitsuhiro, HARAYAMA Hiroshi. Comparative characteristics between calyculin A-induced and thimerosal-induced hyperactivation of cryopreserved bovine spermatozoa. Journal of Reproduction and Development. 2023. 69. 3. 170-177
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SAI Seiken, HARAYAMA Hiroshi. Polyvinyl alcohol, but not bovine serum albumin, promotes the induction of full-type hyperactivation in boar cyclic AMP analog-treated spermatozoa. Animal Science JOurnal. 2022. 93. e13777
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DURITAHALA, SAKASE Mitsuhiro, HARAYAMA Hiroshi. Involvement of Ca2+-ATPase in suppressing the appearance of bovine helically motile spermatozoa with intense force prior to cryopreservation. Journal of Reproduction and Development. 2022. 68. 3. 181-189
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WADA Atsushi, HARAYAMA Hiroshi. Calmodulin is involved in the occurrence of extracellular Ca2+-dependent full-type hyperactivation in boar ejaculated spermatozoa incubated with cyclic AMP analogs. Animal Science Journal. 2021. 92. e13552
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SAHA Soma Rani, SAKASE Mitsuhiro, FUKUSHIMA Moriyuki, HARAYAMA Hiroshi. Effects of digoxin on full-type hyperactivation in bovine ejaculated spermatozoa with relatively lower survivability for incubation with stimulators of cAMP signaling cascades. Theriogenology. 2020. 154. 100-109
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MISC (24):
Books (7):
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繁殖生物学 改訂版(第2版)
株式会社インターズ- 2020
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発生生物学 「哺乳類の受精」
2019
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Capacitation-related events in boar spermatozoa, Animal Frontier Sciences(pp. 37-43)
Hokuto Shobo 2003
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Regulation of head-to-head agglutination in boar spermatozoa by capacitation-related factors. Reproductive Biotechnology: Reproductive biotechnology update and its related physiology (pp. 203-209)
Hokuto Shobo 2001
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Early development of porcine parthenogenetic diploids in-vitro (Reproductive Biotechnology: Reproductive biotechnology update and its related physiology. pp.285-295)
Hokuto Shobo 2001
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Lectures and oral presentations (129):
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ウシ凍結保存精子でのCalyculin-A 誘発性Full-type ハイパーアクチベーションの発生に及ぼすストア作動性チャネル非選択的阻害剤の影響
(第73 回関西畜産学会大会 2023)
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ウシ凍結保存精子でのCalyculin-A誘発性Full-type Hyperactivationの発生におけるストア作動性チャネルの関与
(第116回日本繁殖生物学会大会 2023)
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お父さん牛の精子がお母さんの卵子と どのように受精するのか?
(第116回日本繁殖生物学会大会・市民公開講座「黒毛和牛をもっと増やそう!最新の繁殖生物学研究がお父さん牛にできること」 2023)
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人工授精での受胎率の向上を目指して -ウシ(黒毛和種)精子の新規検査法の開発-
(日本アンドロロジー学会第42回学術大会 特別講演4 2023)
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ブタ射出精子での体外受精能力発現に及ぼす cAMP シグナリング活性化処理の影響
(日本アンドロロジー学会第42回学術大会 2023)
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Education (1):
- - 1992 Kobe University Graduate School of Science and Technology
Professional career (2):
- 農学修士 (神戸大学)
- 博士(農学) (神戸大学)
Awards (7):
- 2024/09 - Japanese Society of Animal Science The 2024 Award for Excellence in Reviewing for Animal Science Journal in 2023, Animal Science Journal Reviewers Award
- 2021/04 - Japanese Society of Animal Science The 2021 Award for Excellence in Reviewing for Animal Science Journal in 2020 Animal Science Journal Reviewers Award
- 2019/03 - Japanese Society of Animal Science The 2019 Award for Excellence in Reviewing for Animal Science Journal in 2018 Animal Science Journal Reviewers Award
- 2017/07 - JSPS 日本学術振興会(JSPS)平成28年度 特別研究員等審査会専門委員(書面担当)の表彰 日本学術振興会(JSPS)平成28年度 特別研究員等審査会専門委員(書面担当)の表彰
- 2012/09 - The Society for Reproduction and Development (SRD) The 2012 SRD Outstanding Research Award Study on intracellular cAMP signaling in mammalian spermatozoa
- 2006/08 - 関西畜産学会 第56回関西畜産学会優秀発表賞(第1位) ブタ精子の頭部におけるcAMP依存性細胞内カルシウム濃度上昇に及ぼす炭酸水素ナトリウムおよびPKA阻害剤の影響
- 2006/04 - American Society of Andrology 2006 Lalor Foundation Award Role of protein kinase C in the cyclic adenosine 3',5'-monophosphate-dependent hyperactivation of boar spermatozoa
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Association Membership(s) (10):
関西アンドロロジーカンファレンス
, 関西生殖医学集談会
, 精子研究会
, 日本生殖医学会
, The Society for the Study of Reproduction
, American Society of Andrology
, 関西畜産学会
, 日本アンドロロジー学会
, 日本繁殖生物学会
, 日本畜産学会
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