DENDA-NAGAI Kaori

デンダカオリ | DENDA-NAGAI Kaori

Affiliation and department：
Job title： Assistant Professor
Other affiliations (1)：

Intractable Disease Research Center, Juntendo University School of Medicine

Research field (3)： Immunology , Pharmacology , Pharmaceuticals - health and biochemistry

Research keywords (4)：糖鎖生物学 , 腫瘍免疫学 , Glycobiology , Cancer Immunology

Research theme for competitive and other funds (10)：

2020 - 2023 Regulation of immune response through the recognition of O-glycans by antigen presenting cells
2013 - 2017 MUC21 glycoforms as the target of cancer diagnosis and therapy
2011 - 2016 Targeting dendritic cell subsets with glycosylated antigens for cancer immunotherapy
2012 - 2015 Regulation of IgA responses against influenza virus
2009 - 2010 Anti-tumor vaccine by the use of antigen targeting to lectins expressed on dendritic cells

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Papers (45)：

Yoshiya Horimoto, May Thinzar Hlaing, Harumi Saeki, Kaori Denda-Nagai, Katrin Ishii-Schrade, Haruhiko Fujihira, Masaaki Abe, Miki Noji, Shigeyuki Shichino, Mitsue Saito, et al. Glycosylation profiles of breast cancer cells may represent clonal variations of multiple organ metastases. Clinical & experimental metastasis. 2024
Dong-Hee Lee, Hyejin Ahn, Hye-In Sim, Eunji Choi, Seunghyun Choi, Yunju Jo, Bohwan Yun, Hyun Kyu Song, Soo Jin Oh, Kaori Denda-Nagai, et al. A CRISPR activation screen identifies MUC-21 as critical for resistance to NK and T cell-mediated cytotoxicity. Journal of experimental & clinical cancer research : CR. 2023. 42. 1. 272-272
Yukari Manome-Zenke, Kaori Denda-Nagai, Ryuichi Murakami, Miki Noji, Naoto Tsuneda, Katrin Beate Ishii-Schrade, Naoki Kanomata, Satoru Arai, Tatsuro Irimura, Shigaku Ikeda. Possible Involvement of Antigen-Presenting Cells Expressing the Macrophage Galactose-Type C-Type Lectin in Inflammatory Skin Diseases. Journal of Investigative Dermatology. 2023
Ryoko Semba, Yoshiya Horimoto, Madoka Sakata-Matsuzawa, Yumiko Ishizuka, Kaori Denda-Nagai, Haruhiko Fujihira, Miki Noji, Hiroko Onagi, Miyu Ichida, Hiroyoshi Miura, et al. Possible correlation of apical localization of MUC1 glycoprotein with luminal A-like status of breast cancer. Scientific reports. 2023. 13. 1. 5281-5281
Retno Murwanti, Kaori Denda-Nagai, Daisuke Sugiura, Kaoru Mogushi, Sandra J. Gendler, Tatsuro Irimura. Prevention of Inflammation-Driven Colon Carcinogenesis in Human MUC1 Transgenic Mice by Vaccination with MUC1 DNA and Dendritic Cells. Cancers. 2023

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MISC (60)：

善家由香理, 伝田香里, 恒田直人, 新井達, 入村達郎, 池田志斈. アトピー性皮膚炎におけるマクロファージガラクトース型C型レクチン陽性自然免疫細胞の関与. 日本皮膚科学会雑誌. 2023. 133. 5. 1365-1365
國府涼香, 倉谷太豪, 高橋優花, 大野詩歩, 真鍋法義, 清水弘樹, 千葉靖典, 伝田香里, 築地信, 入村達郎, et al. MUC1糖ペプチドと抗MUC1抗体MY.1E12の相互作用解析. 日本薬学会年会要旨集. 2022. 142年会. 26PO1-46S
吉田昌宏, 稲垣優希, 人見祐基, 奥輝明, 伝田香里, 入村達郎, 築地信. 腫瘍関連糖鎖抗原を認識する抗体の可変部遺伝子配列の決定と人工抗体の作製. 日本薬学会年会要旨集. 2022. 142年会. 28PO5-01S
Kaori Denda-Nagai, Katrin B. Ishii-Schrade, Yuan Tian, Kyoko Okada, Tatsuro Irimura. Immunohistochemistry of mucin 21. 2021
Kaori Denda-Nagai, Ryuichi Murakami, Tatsuro Irimura. Flow cytometric analysis of macrophage galactose-type C-type lectin 1 and 2 expression by the use of specific monoclonal antibodies. 2021

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Patents (4)：

Books (1)：

感染と免疫第4版
東京化学同人 2017 ISBN:4807908979

Lectures and oral presentations (5)：

抗原提示細胞に発現するマクロファージガラクトース型C型レクチンの炎症性皮膚疾患における役割
(第46回日本分子生物学会年会 2023)
糖鎖付加MUC1を利用したがんワクチンのための基礎的研究:MGLの関与
(糖鎖免疫 Glyco-Immunology 2018 2018)
マクロファージガラクトース型C型レクチン(MGL/CD301)によって制御される免疫応答
(第34回日本糖質学会年会 2015)
マクロファージガラクトース型C型レクチン(MGL/CD301)による炎症と免疫の制御
(第12回糖質科学コンソーシアムシンポジウム 2014)
MGL1/CD301陽性細胞の免疫と炎症の制御における重要性
(糖鎖免疫Glyco-Immunology 2014 2014)

Education (4)：

- 1999 The University of Tokyo Graduate School of Pharmaceutical Sciences
- 1999 The University of Tokyo Graduate School, Division of Pharmaceutical Sciences
- 1995 The University of Tokyo Faculty of Pharmaceutical Sciences Department of Pharmacy
- 1995 The University of Tokyo Faculty of Pharmaceutical Science

Professional career (1)：

Ph. D. (The University of Tokyo)

Work history (5)：

2017/06 - 現在 Juntendo University
2015/04 - 現在 Juntendo University Faculty of Medicine
2014/04 - 2015/03 St. Luke's International University
2007/04 - 2014/03 The University of Tokyo Graduate School of Pharmaceutical Sciences
1999/04 - 2007/03 The University of Tokyo Graduate School of Pharmaceutical Sciences

Association Membership(s) (6)：

THE JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH , 日本サイトカイン学会 , 日本薬学会 , 日本免疫学会 , がん転移学会 , 日本癌学会

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