Rchr
J-GLOBAL ID:200901008090414665
Update date: Sep. 29, 2025
YOSHIHIRO OHTA
オオタ ヨシヒロ | YOSHIHIRO OHTA
Affiliation and department:
Job title:
Professor
Other affiliations (3):
Homepage URL (1):
http://www.tuat.ac.jp/~ohta/
Research field (2):
Cell biology
, Biophysics
Research keywords (1):
Mitochondria, Optical Microscopy
Research theme for competitive and other funds (21):
- 2024 - 2027 Biophysical Analysis of Mitochondrial Signaling Capacity.
- 2019 - 2023 マイクロ/ナノ空間の電気化学的pH制御技術の開発と細胞内ATP合成制御への応用
- 2017 - 2018 電気化学的pH制御によるミトコンドリア中ATP合成の制御
- 2013 - 2015 ミトコンドリアの密集・分散が自身の活性に及ぼす影響
- 2013 - 2015 局所微小力荷重下における近接場蛍光検出による生体組織の生理学応答分析装置の開発
- 2010 - 2012 オルガネライメージングによるネクローシスのシグナル伝達機構の研究
- 2010 - 2012 環境感受性色素による生体膜界面水素イオン濃度・膜電位の同時近接場光学計測法の開発
- 2007 - 2008 画像分離型位相変調法を用いたシナプトソーム活性の計測
- 2006 - 2007 細胞内小器官を基盤に吸着させるためのコーティング剤の探索
- 2005 - 2006 オルガネラ吸着法によるミトコンドリアの高精度機能解析
- 2001 - 2002 単一ミトコンドリアの時間分解計測による活性酸素発生抑制機構の研究
- 1999 - 2001 Development of New Objective Lens with Double Cylinders
- 1998 - 1999 Study on Mechanisms of ATP Synthesis in Single Mitochondria
- 1996 - 1998 蛋白運動とイメージングによる神経ステロイド合成の分子論的解析
- 1996 - 1997 Analysis of Neurosteroid Synthesis in Grial Cells with a combined Imaging System
- 1995 - 1997 細胞の情報伝達を解析する走査型近視野原子間力顕微鏡の開発
- 1996 - 1996 チトクロムP450系及び呼吸系ヘム蛋白質の機能解析
- 1995 - 1996 signal transduction in cells analyzed by imaging and protein rotation
- 1995 - 1995 異種細胞混在系における細胞機能イメージング
- 1994 - 1994 高感度画像計測及び膜蛋白質運動測定による細胞応答の研究
- 1993 - 1994 Multi time-resolved spectroscopic analysis on molecular mechanisms of steroid hormone synthesis in adrenal cortex.
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Papers (55):
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Sadab Sipar Ibban, Jannatul Naima, Ryo Kato, Taichi Kuroda, Yoshihiro Ohta. Antioxidant Effects of Exogenous Mitochondria: The Role of Outer Membrane Integrity. Antioxidants. 2025
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Arima Okutani, Jannatul Naima, Asaka Ogihara, Taihei Motoichi, Ikuroh Ohsawa, Yoshihiro Ohta. A method for isolating and cryopreserving intact mitochondria with improved integrity and functionality. Biophysics and Physicobiology. 2025
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Jannatul Naima, Yoshihiro Ohta. Potassium Ions Decrease Mitochondrial Matrix pH: Implications for ATP Production and Reactive Oxygen Species Generation. International Journal of Molecular Sciences. 2024. 25. 2. 1233-1233
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Mingyin Cui, Momoka Takahashi, Yukun Chen, Bingfu Liu, Yoshihiro Ohta, Takeo Miyake. pH modulation in adhesive cells with a protonic biotransducer. Bioelectrochemistry. 2022. 147. 108202-108202
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Jannatul Aklima, Sawaros Onchaiya, Tomonori Saotome, Punitha Velmurugan, Taihei Motoichi, Jannatul Naima, Yutaka Kuroda, Yoshihiro Ohta. Direct Analysis of Mitochondrial Damage Caused by Misfolded/Destabilized Proteins. International Journal of Molecular Sciences. 2022. 23. 17. 9881-9881
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MISC (40):
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SHIBATA Takahiro, YAMASHITA Saki, KATOH Kaoru, OHTA Yoshihiro. Isolation of Mitochondria by Gentle Cell Membrane Disruption, and their Subsequent Characterization. Seibutsu Butsuri. 2016. 56. 2. 112-115
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松野本宜寛, 石暁磊, 岩崎あすか, 太田善浩. 酸化ストレスによる細胞内ミトコンドリアの内膜透過性遷移の観察. バイオイメージング. 2010. 18. 3. 278-283
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手崎 碧, 太田 善浩. シナプス分離法(単離シナプスの機能解析). Cllinical Neuroscience. 2010. 28. 889-891
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Chisako Fujita, Fumito Ichikawa, Toshiaki Teratani, Gen Murakami, Takahiro Okada, Masaki Shinohara, Suguru Kawato, Yoshihiro Ohta. Direct effects of corticosterone on ATP production by mitochondria from immortalized hypothalamic GT1-7 neurons. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2009. 117. 1-3. 50-55
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池田慶一, 武位教子著. 2-6ミトコンドリアのイメージング. 光る生き物. 2009. -. -. -
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Lectures and oral presentations (111):
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ISOLATION OF INTACT MITOCHONDRIA BY GENTLE SELECTIVE DISRUPTION OF PLASMA MEMBRANES
(Targeting Mitochondria 2022 2022)
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操作とイメージングで検出するミトコンドリア機能
(第43回 生体膜と薬物の相互作用シンポジウム 2022)
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Measurements of electron transfer complex activities in intact mitochondria
(The 60th annual meeting of the Biophysical Society of Japan 2022)
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Observation of membrane potential fluctuations of yeast mitochondria
(The 60th annual meeting of the Biophysical Society of Japan 2022)
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Detection of time-dependent oxidative damages of mitochondrial electron transfer complexes
(The 60th annual meeting of the Biophysical Society of Japan 2022)
more...
Professional career (1):
Work history (1):
Committee career (6):
Association Membership(s) (4):
日本生物物理学会
, 日本バイオイメージング学会
, THE JAPANESE SOCIETY OF MITOCHONDRIAL RESEARCH AND MEDICINE
, 日本生化学会
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