Rchr
J-GLOBAL ID:200901008841716263
Update date: Jan. 18, 2025
Inoue Takayoshi
イノウエ タカヨシ | Inoue Takayoshi
Affiliation and department:
Job title:
Chief Researcher
Homepage URL (1):
https://www.ncnp.go.jp/nin/guide/r6/
Research field (5):
Neuroanatomy and physiology
, Medical biochemistry
, Evolutionary biology
, Developmental biology
, Molecular biology
Research keywords (30):
トランスジェニックマウス
, 発生・分化
, ゲノム
, 細胞接着
, 神経実験形態学
, 脳・神経
, 後脳分節
, 神経冠細胞
, エレクトロポレーション
, 全胚培養
, 遺伝子発現制御
, カドヘリン
, 細胞・組織
, 脳神経疾患
, 高次構造
, BACトランスジェニックマウス
, 遺伝学
, 分子遺伝学
, アルブミン
, ストレス
, プロテオミクス
, プロテオーム解析
, 酸化
, 神経科学
, 進化
, 発生
, 大脳皮質
, evolution
, development
, neocortex
Research theme for competitive and other funds (7):
- 2016 - 2021 Analysis of genes that affect individuality
- 2012 - 2016 Elucidation of cellular and molecular machinery to elaborate the barrel area specific cytoarchitecture in the mouse cerebral cortex
- 2009 - 2011 Molecular basis for the complex neurocristopathy PCWH and mechanisms underlying SOX10 allelic affinity
- 2009 - 2011 Elucidation of molecular machinery for mouse forebrain compartmentalization
- 2006 - 2007 Proteomic Analysis of Psychological Stress and Protein Higher Structures
- 2004 - 2005 マウス後脳分節化過程に発現するカドヘリンの機能解析
- Elucidation of mechanisms of development and evolution assembling the mammal specific cytoarchitecture of cerebral cortex
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Papers (61):
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Kazumi Shimaoka, Kei Hori, Satoshi Miyashita, Yukiko U Inoue, Nao K N Tabe, Asami Sakamoto, Ikuko Hasegawa, Kayo Nishitani, Kunihiko Yamashiro, Saki F Egusa, et al. The microcephaly-associated transcriptional regulator AUTS2 cooperates with Polycomb complex PRC2 to produce upper-layer neurons in mice. The EMBO journal. 2025
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Yukiko Harima, Masafumi Tsurutani, Serika Yamada, Shuntaro Uchida, Kengo Inada, Mitsue Hagihara, Satsuki Irie, Mayo Shigeta, Takaya Abe, Yukiko U. Inoue, et al. Parallel labeled-line organization of sympathetic outflow for selective organ regulation in mice. Nature Communications. 2024. 15. 1
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Ryohei Sakai, Shu Aizawa, Hyeon-Cheol Lee-Okada, Katsunori Hase, Hiromi Fujita, Hisae Kikuchi, Yukiko U. Inoue, Takayoshi Inoue, Chihana Kabuta, Takehiko Yokomizo, et al. The lysosomal membrane protein LAMP2B mediates microlipophagy to target obesity-related disorders. 2024
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Hideo Hagihara, Hirotaka Shoji, Satoko Hattori, Giovanni Sala, Yoshihiro Takamiya, Mika Tanaka, Masafumi Ihara, Mihiro Shibutani, Izuho Hatada, Kei Hori, et al. Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment. eLife. 2024. 12
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Ken-ichi Dewa, Nariko Arimura, Wataru Kakegawa, Masayuki Itoh, Toma Adachi, Satoshi Miyashita, Yukiko U. Inoue, Kento Hizawa, Kei Hori, Natsumi Honjoya, et al. Neuronal DSCAM regulates the peri-synaptic localization of GLAST in Bergmann glia for functional synapse formation. Nature Communications. 2024. 15. 1
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MISC (51):
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大隅典子, 井上(上野)由紀子, 舘花美沙子, 吉川貴子, 稲田仁, 井上高良. ゲノム編集を用いたPA標識マウスによるREST/NRSF局在動態の観察. 日本解剖学会総会・全国学術集会抄録集(CD-ROM). 2023. 128th
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嶋岡可純, 堀啓, 井上由紀子, 郷康弘, 阿部学, 崎村建司, 井上高良, 星野幹雄. 自閉症感受性遺伝子AUTS2はマウス大脳皮質において上層神経細胞の産生に関与する. 日本神経化学会大会抄録集(Web). 2022. 65th
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Yukiko U Inoue, Yoneko Hayase, Mikio Hoshino, Daiki X Sato, Masakado Kawata, Tetsushi Sakuma, Takashi Yamamoto, Takayoshi Inoue. Humanized mouse models to decipher the diversity of nervous system. The CELL. 2021. 53. 7. 52-56
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Yuuki Fujiwara, Viorica Raluca Contu, Chihana Kabuta, Megumu Ogawa, Hiromi Fujita, Hisae Kikuchi, Ryohei Sakai, Katsunori Hase, Mari Suzuki, Ikuko Koyama-Honda, et al. Discovery of a protein uptake pathway in lysosomes. bioRxiv. 2020
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Yuuki Fujiwara, Viorica Raluca Contu, Chihana Kabuta, Megumu Ogawa, Hiromi Fujita, Hisae Kikuchi, Ryohei Sakai, Katsunori Hase, Mari Suzuki, Ikuko Koyama-Honda, et al. Direct uptake mechanism in lysosome required for neuromuscular homeostasis. 2020
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Patents (1):
Books (10):
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動物の事典
朝倉書店 2020
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動物の事典
朝倉書店 2020
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発生生物学 : 基礎から応用への展開
培風館 2019 ISBN:9784563078232
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Bacterial Artificial Chromosome
InTech 2011
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From Molecular Basis to Disease
Wiley-VCH 2008
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Lectures and oral presentations (29):
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有胎盤類特有のzip code配列獲得による放射状グリア細胞内mRNA輸送機構の進化
(日本解剖学会総会・全国学術集会講演プログラム・抄録集 2022)
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Expression Changes of REST/NRSF in Spermatogenesis from Neonatal to Adult Murine Testis
(日本分子生物学会年会プログラム・要旨集(Web) 2021)
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Expression analysis of the autism spectrum disorder-related molecule SHANK3 in the developing mouse brain and synaptic analysis of Shank3-deficient mice
(日本分子生物学会年会プログラム・要旨集(Web) 2021)
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大脳皮質発生過程の放射状グリア細胞におけるCyclinD2のmRNA輸送機構の解析(The molecular mechanism of Cyclin D2 mRNA transport in the radial glial cells during cortical development)
(日本神経精神薬理学会年会・日本生物学的精神医学会年会・日本精神薬学会総会・学術集会合同年会プログラム・抄録集 2020)
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CyclinD2のmRNA輸送による有胎盤類大脳皮質の拡大機構の解明
(日本解剖学会総会・全国学術集会講演プログラム・抄録集 2020)
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Education (3):
- 1993 - 1997 Kyoto University Graduate School of Science
- 1991 - 1993 Kyoto University Graduate School of Science
- - 1991 Kyoto University Faculty of Science
Professional career (1):
Work history (6):
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