Research field (2):
Bioorganic chemistry
, Pharmaceuticals - chemistry and drug development
Research theme for competitive and other funds (5):
2021 - 2024 Optimization of SARS 3CL protease inhibitor and development of anti-COVID-19 drug
2017 - 2020 Development of novel therapeutic agents for schizophrenia based on kynurenine hypothesis
2015 - 2017 Development of novel BACE1 inhibitors based on the N-amidino nitrogen-containing ring structure
2013 - 2016 Design of non-peptide inhibitors based on structure analyses of the protease/inhibitor complex
2013 - 2015 Development of novel BACE1 inhibitors: Structure activity relationship study based on the substrate sequence
Papers (75):
Yuto Kondo, Hiroyuki Kimura, Mamiko Tanaka, Yasunao Hattori, Hidekazu Kawashima, Kazuhiro Takahashi, Hiroyuki Yasui. Mechanistic Insights into the Effect of Sodium Iodide on Copper-Mediated Iododeboronation. Chemistry - A European Journal. 2024
Yuto Kondo, Hiroyuki Kimura, Ryota Chisaka, Yasunao Hattori, Hidekazu Kawashima, Hiroyuki Yasui. One-pot two-step radioiodination based on copper-mediated iododeboronation and azide-alkyne cycloaddition reaction. Chemical Communications. 2024. 60. 6. 714-717
Chiyuki Awahara, Daiki Oku, Kazuya Kobayashi, Yasunao Hattori. Evaluating a Retro-Inverso Type Inhibitor of HTLV-1 Protease as a Competitive Inhibitor. Chemical & pharmaceutical bulletin. 2024. 72. 3. 309-310
Marina Omokawa, Hiroyuki Kimura, Kenji Arimitsu, Yusuke Yagi, Yasunao Hattori, Hidekazu Kawashima, Yuki Naito, Hiroyuki Yasui. Synthesis and Biological Evaluation of a Novel Sugar-Conjugated Platinum(II) Complex Having a Tumor-Targeting Effect. ACS Omega. 2023
Yuto Kondo, Hiroyuki Kimura, Minon Sasaki, Sumina Koike, Yusuke Yagi, Yasunao Hattori, Hidekazu Kawashima, Hiroyuki Yasui. Effect of Water on Direct Radioiodination of Small Molecules/Peptides Using Copper-Mediated Iododeboronation in Water-Alcohol Solvent. ACS Omega. 2023
K. Kobayashi, Y. Hattori, K. Teruya, A. Sanjoh, A. Nakagawa, E. Yamashita, K. Akaji. STRUCTURE ACTIVITY RELATIONSHIP STUDY FOR P1-P1 ' SITE OF TRANSITION STATE MIMIC INHIBITORS FOR BACE1. JOURNAL OF PEPTIDE SCIENCE. 2016. 22. S42-S42
2005 - 2008 Shinshu University Interdisciplinary Graduate School of Science and Technology
2001 - 2003 Shinshu University Graduate School, Division of Agriculture
1997 - 2001 Shinshu University Faculty of Agriculture Bioscience and Biotechnology
Work history (4):
2016 - Kyoto Pharmaceutical University Instrumental Analysis Center
2011 - Kyoto Pharmaceutical University
2009 - Kyoto Prefectural University of Medicine Graduate School of Medical Science
2008 - 米国National Institutes of Health, Visiting Fellow
Association Membership(s) (5):
THE JAPANESE CANCER ASSOCIATION
, The Japanese Peptide Society
, THE PHARMACEUTICAL SOCIETY OF JAPAN
, THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN
, JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY