Rchr
J-GLOBAL ID：200901009590010575   Update date: Jun. 26, 2024

Ago Yukio

アゴウ ユキオ | Ago Yukio
Affiliation and department：
Hiroshima University Department of Cellular and Molecular Pharmacology, Graduate School of Biomedical and Health Sciences

About Hiroshima University Department of Cellular and Molecular Pharmacology, Graduate School of Biomedical and Health Sciences


Job title： Professor
Homepage URL  (2)： https://www.hiroshima-u.ac.jp/dent/research/lab/dentistry/Cellular_and_Molecular_Pharmacology ,  https://www.hiroshima-u.ac.jp/en/dent/research/lab/dentistry/Cellular_and_Molecular_Pharmacology
Research field  (2)： Pharmacology ,  Pharmaceuticals - health and biochemistry
Research keywords  (11)： Glutamate and Glucocorticoid ,  Monoamine ,  Environmental factors ,  Animal models ,  Psychiatric disorders ,  グルココルチコイド ,  グルタミン酸 ,  モノアミン ,  環境因子 ,  動物モデル ,  精神疾患
Research theme for competitive and other funds  (27)：
  • 2023 - 2027 発達神経毒性物質と遺伝要因の両者による自閉スペクトラム症発症に関する基礎研究
  • 2021 - 2024 Development of a control method for depth of anesthesia and/or sedation applied to a selective dopamine receptor subtype ligand.
  • 2020 - 2024 Development of the integrated therapeutic strategy aiming toward drug discovery and pharmacotherapy for treatment-resistant schizophrenia
  • 2021 - 2023 Identification of novel factors mediating the effects of environmental enrichment in the absence of voluntary exercise on psychiatric disorders
  • 2020 - 2023 Pathophysiological significance of neuron-astrocyte implication of PACAP on stress-induced emotional disorder
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Papers (173)：
  • Satoshi Asano, Ami Ono, Kaede Baba, Teru Uehara, Kotaro Sakamoto, Atsuko Hayata-Takano, Takanobu Nakazawa, Souichi Yanamoto, Kotaro Tanimoto, Hitoshi Hashimoto, et al. Blockade of vasoactive intestinal peptide receptor 2 (VIPR2) signaling suppresses cyclin D1-dependent cell-cycle progression in MCF-7 cells. Journal of pharmacological sciences. 2024. 154. 3. 139-147
  • Rei Yokoyama, Yukio Ago, Hisato Igarashi, Momoko Higuchi, Masato Tanuma, Yuto Shimazaki, Takafumi Kawai, Kaoru Seiriki, Misuzu Hayashida, Shun Yamaguchi, et al. (R)-ketamine restores anterior insular cortex activity and cognitive deficits in social isolation-reared mice. Molecular psychiatry. 2024
  • Rei Yokoyama, Momoko Higuchi, Wataru Tanabe, Shinji Tsukada, Hisato Igarashi, Kaoru Seiriki, Takanobu Nakazawa, Atsushi Kasai, Yukio Ago, Hitoshi Hashimoto. Long-lasting anti-despair and anti-anhedonia effects of (S)-norketamine in social isolation-reared mice. Journal of pharmacological sciences. 2024. 154. 2. 72-76
  • Ryota Araki, Ayami Kita, Yukio Ago, Takeshi Yabe. Chronic social defeat stress induces anxiety-like behaviors via downregulation of serotonin transporter in the prefrontal serotonergic system in mice. Neurochemistry International. 2024. 105682-105682
  • Akari Mukai, Masahiro Irifune, Yoshitaka Shimizu, Mitsuru Doi, Yuka Kikuchi, Sotaro Katayama, Kana Oue, Mitsuhiro Yoshida, Yukio Ago, Yoshiyuki Okada, et al. N-methyl-d-aspartate receptors and glycinergic transmission, respectively, mediate muscle relaxation and immobility of pentobarbital in mice. Neuroscience letters. 2023. 802. 137175-137175
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MISC (144)：
  • 吾郷由希夫, 山田めゐ, 宮岡辰典, CHEN Lu, 石本憲司, 樋野展正, 中川晋作, 坂元孝太郎, 浅野智志. Development of mid-size molecule inhibitors of VIPR2 for the treatment of psychiatric disorders. 日本薬学会年会要旨集(Web). 2023. 143rd
  • 山田めゐ, 陳露, 宮岡辰典, 桝谷晃明, 石本憲司, 石本憲司, 樋野展正, 中川晋作, 中川晋作, 浅野智志, et al. 新規選択的VPAC2受容体アンタゴニストペプチドの創製とその中枢薬理作用. 日本薬理学雑誌. 2022. 157. Supplement
  • 竹本智哉, 馬場優志, 北川航平, 永安一樹, 永安一樹, 勢力薫, 勢力薫, 早田敦子, 早田敦子, 笠井淳司, et al. ヒト染色体3q29領域欠失を導入した自閉スペクトラム症モデルマウスの社会性行動異常はオキシトシンにより回復する. 日本薬理学雑誌. 2022. 157. Supplement
  • 山口拓海, 片平海雅, 山口稜太, 石本憲司, 石本憲司, 樋野展正, 樋野展正, 高垣昌子, 大木渉吾, 鈴木壯幸, et al. EGC-M5, a green tea catechin metabolite, alleviates cognitive deficits and depressive-like behaviors in mice. 日本薬学会年会要旨集(Web). 2022. 142nd
  • 馬場優志, 勢力薫, 近藤百香, 北川航平, 竹本智哉, 笠井淳司, 吾郷由希夫, 吾郷由希夫, 永安一樹, 永安一樹, et al. ヒト染色体3q29欠失モデルマウスを用いた精神疾患の分子病態研究. 日本薬理学雑誌. 2021. 156. Supplement
ｍore...
Patents (1)：
  • 放射性炭素標識イミダゾール誘導体
Books (3)：
  • Neuropathology of Drug Addictions and Substance Misuse, Volume 2: Stimulants, Club and Dissociative Drugs, Hallucinogens, Steroids, Inhalants, and International Aspects
    Elsevier 2016
  • Pituitary Adenylate Cyclase Activating Polypeptide - PACAP
    Springer 2016
  • ストレス百科事典「抗うつ薬の作用、グルココルチコイド受容体に対する」
    丸善株式会社 2009
Education (3)：
  • 2003 - 2005 Osaka University Graduate School of Pharmaceutical Sciences Ph.D. course
  • 2001 - 2003 Osaka University Graduate School of Pharmaceutical Sciences M.S. course
  • 1997 - 2001 Osaka University Faculty of Pharmaceutical Sciences
Professional career (1)：
  • Ph.D. (Osaka University)
Work history (12)：
  • 2020/03 - 現在 Graduate School of Biomedical and Health Sciences, Hiroshima University Department of Cellular and Molecular Pharmacology Professor
  • 2018/06 - 2020/02 (兼任)大阪大学国際医工情報センター
  • 2018/05 - 2020/02 (兼任)大阪大学薬学研究科附属創薬センター 次世代食品開発プロジェクト/三井農林共同研究講座
  • 2018/04 - 2020/02 Graduate School of Pharmaceutical Sciences, Osaka University Laboratory of Biopharmaceutics Associate Professor
  • 2017/04 - 2020/02 (兼任)大阪大学歯学研究科薬理学教室
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Committee career (14)：
  • 2019/02 - 現在 日本薬学会 代議員
  • 2019/01 - 現在 Pharmacology, Biochemistry and Behavior誌 Editorial Board Member
  • 2018/11 - 現在 予防薬理学研究所 特別会員
  • 2018/10 - 現在 Journal of Pharmacological Sciences誌 Editorial Board Member
  • 2018/05 - 現在 日本薬学会 近畿支部委員
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Awards (12)：
  • 2019/10 - Japanese Society of Neuropsychopharmacology Neuropsychopharmacology Reports Reviewer Award 2019
  • 2018/03 - The Japanese Pharmacological Society Journal of Pharmacological Sciences Excellent Reviewer Award 2017
  • 2016/07 - Japanese Society of Neuropsychopharmacology JSNP Excellent Presentation Award for CINP 2016
  • 2016/05 - The Society for the Study of GPCR Matsuo Award for Encouragement of Young Investigators
  • 2014/07 - Osaka University Osaka University (Japan) Presidential Awards for Encouragement
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Association Membership(s) (11)：
トランスポーター研究会 ,  老化促進モデルマウス(SAM)学会 ,  THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM ,  American Society for Neurochemistry ,  Collegium Internationale Neuro-Psychopharmacologicum ,  Society for Neuroscience ,  The Pharmaceutical Society of Japan ,  THE JAPANESE SOCIETY FOR NEUROCHEMISTRY ,  THE JAPAN NEUROSCIENCE SOCIETY ,  THE JAPANESE SOCIETY OF NEUROPSYCHOPHARMACOLOGY ,  THE JAPANESE PHARMACOLOGICAL SOCIETY
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