Rchr
J-GLOBAL ID:200901009610377764   Update date: Jun. 09, 2020

Itoh Motoyuki

イトウ モトユキ | Itoh Motoyuki
Affiliation and department:
Homepage URL  (1): http://www.p.chiba-u.jp/lab/seika/index.html
Research field  (5): Laboratory animal science ,  Pharmaceuticals - health and biochemistry ,  Developmental biology ,  Cell biology ,  Molecular biology
Research keywords  (5): zebrafish neural development Notch signaling Wnt signaling ,  Dementia ,  metabolism ,  Aging ,  Brain function
Research theme for competitive and other funds  (7):
  • 2018 - 2020 Notch・Mib1経路によるエネルギー代謝調節の分子基盤研究
  • 2018 - 2018 モデル動物等研究コーディネーティングネットワークによる希少・未診断疾患の病因遺伝子変異候補の機能解析研究
  • 2015 - 2016 CADASIL型Notch3タンパク質の老化と毒性機序の解明
  • 2013 - 2015 Notchシグナルの人為操作を目指した新規ツールと活性測定法の創出
  • 2013 - 2014 翻訳後修飾によるNotchシグナル活性調節機構の解明
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Papers (28):
  • Kuwabara S, Yamaki M, Yu H, Itoh M. Notch signaling regulates the expression of glycolysis-related genes in a context-dependent manner during embryonic development. Biochemical and biophysical research communications. 2018. 503. 2. 803-808
  • Kenta Umehara, Yuchen Sun, Satoshi Hiura, Koki Hamada, Motoyuki Itoh, Keita Kitamura, Motohiko Oshima, Atsushi Iwama, Kosuke Saito, Naohiko Anzai, Kan Chiba, Hidetaka Akita, Tomomi Furihata. A New Conditionally Immortalized Human Fetal Brain Pericyte Cell Line: Establishment and Functional Characterization as a Promising Tool for Human Brain Pericyte Studies. Molecular neurobiology. 2018. 55. 7. 5993-6006
  • Yang P, Kajiwara R, Tonoki A, Itoh M. Successive and discrete spaced conditioning in active avoidance learning in young and aged zebrafish. Neuroscience research. 2018. 130. 1-7
  • Mizoguchi T, Ikeda S, Watanabe S, Sugawara M, Itoh M. Mib1 contributes to persistent directional cell migration by regulating the Ctnnd1-Rac1 pathway. Proceedings of the National Academy of Sciences of the United States of America. 2017. 114. 44. E9280-E9289
  • Yoneyama T, Arai MA, Akamine R, Koryudzu K, Tsuchiya A, Sadhu SK, Ahmed F, Itoh M, Okamoto R, Ishibashi M. Notch Inhibitors from Calotropis gigantea That Induce Neuronal Differentiation of Neural Stem Cells. Journal of natural products. 2017. 80. 9. 2453-2461
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MISC (12):
Education (2):
  • 1991 - 1993 Osaka University Graduate School of Pharmaceutical Sciences
  • 1987 - 1991 Osaka University
Professional career (1):
  • Ph.D (Osaka University)
Work history (6):
  • 2012/05 - Chiba University
  • 2011/04 - Nagoya University
  • 2006/11 - Nagoya University
  • 2003/07 - Nagoya University
  • 1996/04 - Osaka University
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Association Membership(s) (2):
The Molecular Biology Society of Japan ,  The Japanese Society of Developmental Biologists
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