Rchr
J-GLOBAL ID：200901009728847390
Update date: Nov. 16, 2024
Kitamoto Tetsuyuki
キタモト テツユキ | Kitamoto Tetsuyuki
Affiliation and department：
Job title：
Professor
Homepage URL (2)：
http://db.tohoku.ac.jp/whois/detail/5504bd8a452cb2db141cee7971c3cdd8.html
,
http://db.tohoku.ac.jp/whois/e_detail/5504bd8a452cb2db141cee7971c3cdd8.html
Research field (1)：
Experimental pathology
Research theme for competitive and other funds (42)：
- 2019 - 2022 International study to establish a new prion identified with fatal familial or sporadic insomnia.
- 2019 - 2021 Study to establish the new classification of thalamic Creutzfeldt-Jakob disease
- 2018 - 2021 Study to establish the bioassay system for peripheral route infection of various prions
- 2014 - 2019 Molecular bases of pathogenic proteins and mechanisms of the propagation
- 2015 - 2018 Rapid diagnosis of aqcuired Creutzfeldt-jakob disease with protein misfolding cyclic anplification
- 2013 - 2017 Study for highly sensitive PMCA amplification with vCJD prions
- 2014 - 2016 Is thalamic CJD a sporadic form of fatal familial insomnia?
- 2012 - 2014 new classification of sporadic CJD with MV2.
- 2010 - 2012 To study the molecular mechanism of prion protein conversion
- 2011 - 2011 To establish a rapid diagnostic test in a vCJD patient with Codon 129 Val/Val
- 2006 - 2008 Study of the pathomechanism in the prion infection
- 2004 - 2004 ヤコブ病に対する実験的治療法に関する国際連絡会議の企画
- 2002 - 2002 プリオン蛋白の神経障害機構とGPIアンカーの役割
- 2001 - 2002 Analysis of the influence of residue 219 polymorphism of prion protein on human prion diseases
- 2000 - 2002 プリオン蛋白特異的モノクローナル抗体を用いたプリオン病の血清学的診断方法の確立
- 2000 - 2002 Detection of prion infectivity of vibrinogen in human blood
- 2000 - 2002 Transmission experiment of the model mouse expressed with the secretary from of the prion protein
- 2001 - 2001 プリオン蛋白の神経障害機構とGPIアンカーの役割
- 2000 - 2001 Bioassay for human prions with the follicular dendritic cells
- 2000 - 2001 変異プリオン蛋白のプリオン増殖抑制効果とその遺伝子治療への応用
- 1999 - 2001 Analyois of infectivity in the blood from patients with prion disease
- 1999 - 2000 Analyses of prion structure using deletion mutants of prion protein
- 1998 - 1999 Cellular Distribution of Prion Protein
- 1997 - 1999 Transmission Experiment with transgenic model
- 1997 - 1998 Molecular pathogenesis of transmissible spongiform encephalopathy
- 1997 - 1997 家族制アルツハイマー病原因遺伝子presenilin-1結合因子の探索
- 1996 - 1997 A production of animal model for neurofibrillary tangles of Alzheimer's disease
- 1996 - 1996 種特異的プリオン蛋白結合因子の同定
- 1995 - 1996 ApolipoproteinE gene polymorphism in frontotemporal dementia in Japan
- 1994 - 1996 Hypoxic brain damage : MR imaging findings and its correlation with histological findings
- 1994 - 1996 The establishment of prion protein humanaized mice using homologous recombination
- 1995 - 1995 ヒトプリオン蛋白過剰発現モデルの確立
- 1994 - 1994 SCIDマウスにおけるプリオン病耐性のメカニズム
- 1994 - 1994 アルツハイマー病脳内蓄積物質の形成機序
- 1993 - 1994 Study on pathologic mechanism of wild or mutant prion protein gene.
- 1993 - 1993 CJD感染因子の軸索内輸送と濾胞樹状細胞の役割
- 1992 - 1993 Study on the mechanism of prion protein accumulations in follicular dendritic cells.
- 1991 - 1992 Identification of synaptic accumulation of prion proten in Creutzfeldt-Jakob disease.
- 1990 - 1992 Development of a congenic strain on the mouse prion protein gene
- 1990 - 1991 Studies on polymorphism of the prion protein gene in familial Creutzfeldt-Jakob disease.
- 1989 - 1990 Establishment of Prion Protein Immunoassay for Creutzfeldt-Jakob Disease.
- 1988 - 1989 Comparative study on cerebral amyloids of senile dementia and Creutzfeldt-Jakob disease.
Show all
Papers (341)：
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Toshiaki Nonaka, Ryusuke Ae, Koki Kosami, Hiroya Tange, Miho Kaneko, Takehiro Nakagaki, Tsuyoshi Hamaguchi, Nobuo Sanjo, Yoshikazu Nakamura, Tetsuyuki Kitamoto, et al. A Retrospective Cohort Study of a Newly Proposed Criteria for Sporadic Creutzfeldt-Jakob Disease. Diagnostics. 2024. 14. 21. 2424-2424
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Akiko Uchino, Yuko Saito, Saori Oonuma, Shigeo Murayama, Saburo Yagishita, Tetsuyuki Kitamoto, Kazuko Hasegawa. An autopsy case of variably protease-sensitive prionopathy with Met/Met homogeneity at codon 129. Neuropathology : official journal of the Japanese Society of Neuropathology. 2023. 43. 6. 486-495
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Yuki Muroga, Atsuhiko Sugiyama, Hiroki Mukai, Jun Hashiba, Hajime Yokota, Katsuya Satoh, Tetsuyuki Kitamoto, Jiaqi Wang, Shoichi Ito, Satoshi Kuwabara. Cerebral cortex swelling in V180I genetic Creutzfeldt-Jakob disease: comparative imaging study between sporadic and V180I genetic Creutzfeldt-Jakob disease in the early stage. Prion. 2023. 17. 1. 105-110
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Midori Watanabe, Kosei Nakamura, Rie Saito, Atsuko Takeuchi, Tetsuya Takahashi, Tetsuyuki Kitamoto, Osamu Onodera, Akiyoshi Kakita. V180I genetic Creutzfeldt-Jakob disease: Severe degeneration of the inferior olivary nucleus in an autopsied patient with identification of the M2T prion strain. Neuropathology : official journal of the Japanese Society of Neuropathology. 2023
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Ayano Shima, Kenji Sakai, Fumio Yamashita, Tsuyoshi Hamaguchi, Tetsuyuki Kitamoto, Makoto Sasaki, Masahito Yamada, Kenjiro Ono. Vacuoles related to tissue neuron-astrocyte ratio and infiltration of macrophages/monocytes contribute to hyperintense brain signals on diffusion-weighted magnetic resonance imaging in sporadic Creutzfeldt-Jakob disease. Journal of the neurological sciences. 2023. 447. 120612-120612
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MISC (234)：
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Hitaru Kishida, Atsushi Kobayashi, Kenta Teruya, Hiroshi Doi, Naohisa Ueda, Fumiaki Tanaka, Yoshiyuki Kuroiwa, Piero Parchi, Shirou Mohri, Tetsuyuki Kitamoto. Transmission experiments verify sporadic V2 prion in a patient with E200K mutation. Acta Neuropathologica. 2024. 147. 1
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Yuji Nakayama, Terunori Sano, Yutaka Suto, Tadashi Adachi, Masashi Mizutani, Katsuya Sato, Atsuko Takeuchi, Tetsuyuki Kitamoto, Takafumi Miyachi, Masaki Takao. An autopsy of a case of sporadic Creutzfeldt-Jakob disease with MM1+2C+2T. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. 2022. 81. 6. 483-483
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松林泰毅, 赤座実穂, 林祐一, 浜口毅, 佐藤克也, 北本哲之, 山田正仁, 山田正仁, 下畑享良, 横田隆徳, et al. 孤発性クロイツフェルト・ヤコブ病の早期脳波上の正中矢状面の高振幅鋭波,lateralized periodic dischargesの早期診断への影響. Neuroinfection (Web). 2022. 27. 2
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佐藤翔紀, 岩田育子, 濱田晋輔, 白井慎一, 松島理明, 矢口裕章, 佐藤克也, 北本哲之, 森若文雄, 水澤英洋, et al. サーベイランス結果に基づく北海道におけるsporadic Creutzfeldt-Jakob diseaseの疫学. 日本神経学会学術大会プログラム・抄録集. 2022. 63rd
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鈴木哲, 中馬越清隆, 石井一弘, 佐藤克也, 北本哲之, 玉岡晃. 地理的障害で発症したプリオン蛋白V180I変異を有する遺伝性Creutzfeldt-Jakob病の71歳男性例. 日本内科学会関東支部関東地方会. 2021. 668th
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Books (1)：
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PRIONS-Food and Drug Safety
Springer 2005
Lectures and oral presentations (8)：
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セッション2:プリオン現象の解明と制御1 プリオン病の病態:モデル動物から分子まで
(大阪大学蛋白質研究所セミナー「蛋白質立体構造を基盤とするプリオン現象の解明と制御」 2009)
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プリオン病(Overview)・・・歴史(50年史)・診断・治療・予防
(第50回日本神経学会総会 2009)
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CJD surveillance in Japan and genetic vulnerability in vCJD infection
(CJD International Consulation Meeting 2008)
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輸血とプリオン病・最近の話題
(第9回 大分血液輸血研究会 2008)
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プリオン感染の分子機構
(第97回日本病理学会総会 2008)
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Professional career (1)：
- Ph.D. (Kyushu University)
Committee career (4)：
- 2008/05 - 2011/06 日本神経病理学会 理事
- 2008/05 - 2011/06 日本神経病理学会 理事
- 1992/01 - 2008/01 Neuropathology Society 評議員
- 1992/01 - 2008/01 日本神経学会 評議員
Association Membership(s) (2)：
日本神経病理学会(2008/05-2011/06 理事)
, Neuropathology Society(1992/01-2008/01 )
