Rchr
J-GLOBAL ID:200901009844169022   Update date: Mar. 20, 2024

Matsumoto Kunio

マツモト クニオ | Matsumoto Kunio
Affiliation and department:
Other affiliations (1):
  • ナノ生命科学研究所  教授
Homepage URL  (1): http://www.kanazawa-u.ac.jp/~ganken/shuyoudoutaiseigyo/index.html
Research field  (2): Tumor biology ,  Functional biochemistry
Research keywords  (9): Synthetic HGF ,  Macrocyclic peptide ,  Tumor microenvironment ,  HGF ,  転移 ,  細胞増殖因子 ,  MET ,  Metastasis ,  Growth Factor
Research theme for competitive and other funds  (64):
  • 2021 - 2024 Discovery and validation of high-performance recombinant ligands
  • 2022 - 2024 環状ペプチド基盤プラットフォーム分子技術によるイメージング診断・治療用高機能分子創成と検証
  • 2019 - 2022 Tumor microenvironment for metastasis and drug resistance proved by advanced macrocyclic peptide technology
  • 2020 - 2022 有用タンパク質の高発現細胞の構築
  • 2016 - 2022 抗HGF特殊環状ペプチドのイメージング活用創薬
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Papers (361):
  • Ryu Imamura, Hiroki Sato, Dominic Chih-Cheng Voon, Takayoshi Shirasaki, Masao Honda, Makoto Kurachi, Katsuya Sakai, Kunio Matsumoto. Met receptor is essential for MAVS-mediated antiviral innate immunity in epithelial cells independent of its kinase activity. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 40. e2307318120
  • Junichi Taira, Miho Yamaguchi, Anju Tashiro, Asuka Kida, Ko Suzuki, Katsuya Sakai, Kunio Matsumoto, Shunsuke Aoki. Computer-Assisted Identification of Inhibitor with Novel Pharmacophore Targeting First Kringle Domain of Hepatocyte Growth Factor. ChemistrySelect. 2023. 8. 36
  • Michiru Nishita, Koki Kamizaki, Kyoka Hoshi, Kana Aruga, Ikumi Nishikaku, Hiroshi Shibuya, Kunio Matsumoto, Yasuhiro Minami. Rho family small GTPase Rif regulates Wnt5a-Ror1-Dvl2 signaling and promotes lung adenocarcinoma progression. Journal of Biological Chemistry. 2023. 105248-105248
  • Naoya Kawakami, Hiroki Sato, Naohiro Terasaka, Kunio Matsumoto, Hiroaki Suga. MET-Activating Ubiquitin Multimers. Angewandte Chemie International Edition. 2023
  • Shota Warashina, Hiroki Sato, Maki Zouda, Maiko Takahashi, Yasuhiro Wada, Toby Passioura, Hiroaki Suga, Yasuyoshi Watanabe, Kunio Matsumoto, Hidefumi Mukai. Two-Chain Mature Hepatocyte Growth Factor-Specific Positron Emission Tomography Imaging in Tumors Using 64Cu-Labeled HiP-8, a Nonstandard Macrocyclic Peptide Probe. Molecular pharmaceutics. 2023. 20. 4. 2029-2038
more...
MISC (143):
  • Hiroki Sato, Katsuya Sakai, Ryu Imamura, Kunio Matsumoto. HGF conversion in bronchial epithelial cells triggers pre-metastatic niche formation in the lung. CANCER SCIENCE. 2022. 113. 1142-1142
  • Hiroki Sato, Ryu Imamura, Katsuya Sakai, Hiroko Oshima, Masanobu Oshima, Kazuhiro Murakami, Yumi Terakado, Yukinari Kato, Seiji Yano, Kunio Matsumoto. Roles of Mature HGF in Gastric Tissue Regeneration and Tumorigenesis. CANCER SCIENCE. 2021. 112. 422-422
  • 藁科翔太, 佐藤拓輝, 造田真希, 酒井克也, PASSIOURA Toby, 和田康弘, 菅裕明, 松本邦夫, 渡辺恭良, 向井英史, et al. Development of a macrocyclic peptide PET probe for activated HGF molecular imaging aimed at cancer precision diagnosis. JSMI Report. 2021. 14. 1
  • 日野直也, 松田樹生也, 真流玄武, 酒井克也, 酒井克也, 今村龍, 今村龍, 青木一洋, 寺井健太, 平島剛志, et al. Unleashing mechanical constraint switches growth factor signaling dynamics underlying leader cell specification during collective cell migration. 日本細胞生物学会大会(Web). 2021. 73rd
  • 梶原健太郎, 山野荘太郎, 青木一洋, 奥崎大介, 松本邦夫, 岡田雅人. Spatiotemporal regulation of Src signaling in compensatory renal growth. 日本細胞生物学会大会(Web). 2021. 73rd
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Patents (1):
  • がんのバイオマーカーおよびがんの発症を判定する方法
Books (4):
  • 皮膚悪性腫瘍(第2版)上 - 基礎と臨床の最新研究動向 -
    日本臨床社 2021
  • プレシジョンがん診断を指向した活性型HGF 分子イメージング用環状ペプチドPET プローブの開発.
    JSMI Report 2021
  • セルフリーな再生医療(再生誘導剤)の展望
    CMC出版 2020
  • 特殊環状ペプチドによる人工細胞増殖因子・阻害分子の創成と応用
    シーエムシー出版 2019
Lectures and oral presentations  (81):
  • 高機能増殖因子: ネオバイオロジクスの創成と応用.
    (第13回シグナルネットワーク研究会. 2023)
  • cMetキナーゼドメイン両端領域の活性制御機構.
    (第60回ペプチド討論会. 2023)
  • Application of Macrocyclic Peptides for Cancer Imaging Diagnosis and Therapeutics.
    (第83回 日本癌学会総会. 2023)
  • バイオベンチャー起業の思いと大学発スタートアップ創出のために.
    (金沢大学イノベーションシンポジウム2023夏 2023)
  • アカデミアでの研究とスタートアップの意義.
    (第27回 日本がん分子標的治療学会. 2023)
more...
Works (4):
  • PGsの再生薬理作用におけるHGF(肝細胞増殖因子)の役割とメカニズム
    2008 -
  • Role of HGF in pharmaceutical actions of PGs in tissue regeneration
    2008 -
  • HGF蛋白質及びNK4蛋白質を用いた難治性疾患治療法の開発
    2007 -
  • Therapeutic approach with HGF and NK4
    2007 -
Education (4):
  • - 1986 Osaka University
  • - 1986 Osaka University Graduate School, Division of Natural Science Biochemistry
  • - 1981 Kanazawa University Faculty of Science Department of Biology
  • - 1981 Kanazawa University Faculty of Science Biology
Professional career (1):
  • Ph.D. (Osaka University)
Work history (17):
  • 2022/04 - 現在 Vise President
  • 2017/10 - 現在 Kanazawa University
  • 2007/04 - 現在 Kanazawa University Cancer Research Institute
  • 1996/04 - 2007/03 Osaka University Graduate School of Medicine
  • 2001 - 2007 : Associate Professor Associate Professor
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Awards (16):
  • 2022/11 - Kanazawa City Kanazawa City Cultural Award
  • 2016 - 日本学術振興会 科研費審査委員表彰
  • 2014 - The Commendation for Science and Technology by MEXT, Prizes for Science and Technology The Commendation for Science and Technology by MEXT, Prizes for Science and Technology
  • 2006 - Nature Medicine-AnGesMG BioMedical Award Main Award
  • 2002 - 第3回バイオビジネスコンペJAPAN審査委員特別賞
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Association Membership(s) (3):
THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE JAPANESE CANCER ASSOCIATION
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