Rchr
J-GLOBAL ID：200901009923564735
Update date: Nov. 12, 2024
Takashima Akihiko
タカシマ アキヒコ | Takashima Akihiko
Affiliation and department：
Research field (1)：
Neuroscience - general
Research keywords (3)：
aging
, neurodegeneration
, neuroscience
Research theme for competitive and other funds (2)：
- 2018 - 2023 Research on the molecular mechanism of singularity phenomenon in neurological disorders
- 2014 - 2019 Mechanism of tau protein aging and neurodegeneration
Papers (189)：
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Yoshiyuki Soeda, Emi Hayashi, Naoko Nakatani, Shinsuke Ishigaki, Yuta Takaichi, Taro Tachibana, Yuichi Riku, James K. Chambers, Riki Koike, Moniruzzaman Mohammad, et al. A novel monoclonal antibody generated by immunization with granular tau oligomers binds to tau aggregates at 423-430 amino acid sequence. Scientific Reports. 2024. 14. 1
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Yoshiyuki Soeda, Hideaki Yoshimura, Hiroko Bannai, Riki Koike, Isshin Shiiba, Akihiko Takashima. Intracellular tau fragment droplets serve as seeds for tau fibrils. Structure (London, England : 1993). 2024
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Hiroyuki Morino, Takashi Kurashige, Yukiko Matsuda, Maiko Ono, Naruhiko Sahara, Tomohiro Miyasaka, Yoshiyuki Soeda, Hitoshi Shimada, Yu Yamazaki, Tetsuya Takahashi, et al. Clinical and Pathological Features of FTDP-17 with MAPT p.K298_H299insQ Mutation. Movement disorders clinical practice. 2024
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Hiroko Bannai, Akihiko Takashima, Yoshiyuki Soeda, Hideaki Yoshimura, Gen Matsumoto, Naruhiko Sahara, Michio Hiroshima, Mitsuru Hattori, Takeharu Nagai. Research on the molecular mechanism of singularity phenomenon in neurological disorders. Biophysics and Physicobiology. 2024
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Riki Koike, Yoshiyuki Soeda, Atsushi Kasai, Yusuke Fujioka, Shinsuke Ishigaki, Akihiro Yamanaka, Yuta Takaichi, James K Chambers, Kazuyuki Uchida, Hirohisa Watanabe, et al. Path integration deficits are associated with phosphorylated tau accumulation in the entorhinal cortex. Brain communications. 2024. 6. 1. fcad359
ｍore...
MISC (88)：
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阿野泰久, 秋山栞里, 綾部達宏, 大屋怜奈, 高島明彦. 乳由来ペプチドのβラクトリンはアストロサイトのROS産生およびドーパミン分解を抑制する. 日本栄養・食糧学会大会講演要旨集. 2022. 76th
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添田義行, 高島明彦. Role of tau aggregates and development of aggregation inhibitors. 月刊細胞. 2021. 53. 1
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Yuta Takaichi, Yasuhisa Ano, James Ken Chambers, Kazuyuki Uchida, Akihiko Takashima, Hiroyuki Nakayama. Immunohistochemical detection of phosphorylated alpha-synuclein in the brain of a tauopathy model, rTg4510 mice. BRAIN PATHOLOGY. 2019. 29. 79-79
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阿部将志, 添田義之, 楊金緯, 立崎仁, 高島明彦. 植物由来抽出物を使ったタウ凝集阻害剤のスクリーニング. Dementia Japan. 2019. 33. 4
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前田純宏, 坂内博子, 坂内博子, 高島明彦, 周智, 岡野栄之. 一分子イメージングによるヒトiPSC由来神経におけるタウタンパク質減少効果の確認. Dementia Japan. 2019. 33. 4
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Education (2)：
- - 1981 九州大学大学院
- - 1979 Kyushu University School of Sciences Department of Biology
Professional career (1)：
Association Membership(s) (2)：
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