Kubota Yoshitsugu

• PI3-kinaseを介するシグナル伝達
• チロシンキナーゼを介する細胞内情報伝達と血球の増殖,分化
• 造血因子の細胞内シグナル伝達の研究
• Signal transduction mediated by PI3-kinase
• Tyrosine kinase-mediated signal transduction involved in hematopoietic cell proliferation and differentiation
Signal transduction of hematopoietic growth factors

• Takamichi Shintani, Fusako Ohara-Waki, Akira Kitanaka, Terukazu Tanaka, Yoshitsugu Kubota. Cbl negatively regulates erythropoietin-induced growth and survival signaling through the proteasomal degradation of Src kinase. BLOOD CELLS MOLECULES AND DISEASES. 2014. 53. 4. 211-218
• Yasuhiko Ohta, Akira Kitanaka, Keichiro Mihara, Osamu Imataki, Hiroaki Ohnishi, Terukazu Tanaka, Tomohiko Taminato, Yoshitsugu Kubota. Expression of CD38 with intracellular enzymatic activity: a possible explanation for the insulin release induced by intracellular cADPR. MOLECULAR AND CELLULAR BIOCHEMISTRY. 2011. 352. 1-2. 293-299
• Yoshitsugu Kubota, Masato Waki. Chronic myeloid leukemia with a novel four-way t(6;13;9;22)(p21;q32;q34;q11.2) successfully treated with imatinib mesylate. CANCER GENETICS AND CYTOGENETICS. 2010. 201. 2. 135-136
• Yoshitsugu Kubota, Masato Waki. Chronic myeloid leukemia with a novel four-way t(6;13;9;22)(p21;q32;q34;q11.2) successfully treated with imatinib mesylate. CANCER GENETICS AND CYTOGENETICS. 2010. 201. 2. 135-136
• Tetsuya Fukumoto, Yoshitsugu Kubota, Akira Kitanaka, Genji Yamaoka, Fusako Ohara-Waki, Osamu Imataki, Hiroaki Ohnishi, Toshihiko Ishida, Terukazu Tanaka. Gab1 transduces PI3K-mediated erythropoietin signals to the Erk pathway and regulates erythropoietin-dependent proliferation and survival of erythroid cells. CELLULAR SIGNALLING. 2009. 21. 12. 1775-1783

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• 1974 - 1980 Okayama University Medical School Faculty of Medicine
• - 1980 Okayama University Faculty of Medicine 医学

• 1980 M.D., 1990 Ph.D.

• 日本造血細胞移植学会 評議員
• 日本輸血学会 評議員
• 日本血液学会 代議員
• Japan Society for Hematopoietic Cell Transplantation 評議員
• Japan Society of Blood Transfusion 評議員
Japanese Society of Hematology 代議員

THE JAPANESE SOCIETY FOR AIDS RESEARCH ,  日本感染症学会 ,  American society of hematology ,  日本輸血細胞治療学会 ,  臨床血液学会 ,  日本血液学会 ,  日本内科学会 ,  Japan Society for Hematopoietic Cell Transplantation ,  Japanese Society of Laboratory Medicine ,  American society of hematology ,  Japan Society of Blood Transfusion ,  Japanese Society of Clinical Hematology ,  Japanese Cancer Association ,  Japanese Society of Hematology ,  Japanese Society of Internal Medicine