Arimoto Hirokazu

アリモトヒロカズ | Arimoto Hirokazu

Affiliation and department：
Job title： Professor
Other affiliations (1)：

Research field (1)： Molecular biochemistry

Research keywords (6)： AUTACs , 天然物合成化学 , バンコマイシン , 8-ニトロcGMP , オートファジー , .

Research theme for competitive and other funds (47)：

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Papers (81)：

Daiki Takahashi, Taiichi Ora, Shigekazu Sasaki, Naoki Ishii, Toshio Tanaka, Takumi Matsuda, Mutsuki Ikeda, Jun Moriyama, Nobuo Cho, Hiroshi Nara, et al. Second-Generation AUTACs for Targeted Autophagic Degradation. Journal of Medicinal Chemistry. 2023. 66. 12342-12372
Azusa Yugeta, Hiroki Arai, Daiki Takahashi, Nami Haruta, Asako Sugimoto, Hirokazu Arimoto. C. elegans ATG-5 mutants associated with ataxia. microPublication biology. 2023. 2023
Daiki Takahashi, Hirokazu Arimoto. p62 Phase-Separation as the Foundation of Autophagy-Based Degraders. Biochemistry. 2022. 62. 559-560
Daiki Takahashi, Hirokazu Arimoto. Selective autophagy as the basis of autophagy-based degraders. Cell Chemical Biology. 2021. 28. 7. 1061-1071
Shota Asano, Kaori Itto-Nakama, Hirokazu Arimoto. Carbamate as an accelerating group in intermolecular Pauson-Khand reaction. Tetrahedron Letters. 2020. 61. 24. 151974

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MISC (28)：

Daiki Takahashi, Hirokazu Arimoto. Invention and potential applications of AUTAC, a novel strategy based on selective autophagy. 2022. 32. 4. 201-206
Daiki Takahashi, Hirokazu Arimoto. Autophagy Modulators and Human diseases. CSJ Current Review 39: Biomolecules and Diseases. 2021. 115-120
Daniel J. Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Steffen Abel, Hagai Abeliovich, Marie H. Abildgaard, Yakubu Princely Abudu, Abraham Acevedo-Arozena, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 2021. 17. 1. 1-382
AUTACs: autophagy mediated degraders. Experimental Medicine. 2020. 38. 14. 2331-2336
高橋大輝, 有本博一. マクロオートファジーの化合物による制御-創薬を目指して. 医学のあゆみ. 2020. 272. 9. 958-963

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Patents (17)：

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Books (10)：

Dramatic Synthetic Organic Chemistry
2023 ISBN:9784759823363
天然物の化学II(科学のとびら64): 自然からの贈り物
2018
生命機能に迫る分子化学:生命分子を真似る、飾る、超える
化学同人 2018
8-Nitro-cGMP: A Novel Protein-Reactive cNMP and Its Emerging Roles in Autophagy (Handbook of Experimental Pharmacology)
Springer 2017
天然物の化学(科学のとびら60): 魅力と展望
東京化学同人 2016

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Lectures and oral presentations (76)：

Targeting Selective Autophagy by AUTAC Degraders
(13th International Symposium on Bioorganic Chemistry (ISBOC-13) 2023)
オートファジーを活用する標的分解薬
(第42回日本認知症学会学術集会 2023)
Targeting Selective Autophagy by AUTAC degraders
(2nd Targeted Protein Degradation Conference in Japan 2023)
Targeting Selective Autophagy by AUTAC degraders
(Keystone Symposia: Autophagy and Neurodegeneration 2023)
標的選択的なオートファジー制御技術の開発
(有機合成化学協会企業冠賞受賞講演会(2021年度受賞) 2022)

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Education (2)：

Professional career (1)：

Work history (4)：

Committee career (10)：

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Awards (8)：

2021/12 - The Society of Synthetic Organic Chemistry, Japan SSOCJ Kaneka Award for Life Science (2021)
2021/09 - US National Academy of Medicine Healthy Longevity Grand Challenge(HLGC)Healthy Longevity Global Competition International Catalyst Award Compounds that suppress the aging process through selective autophagy
2016/10/01 - 慶應義塾大学理工学部矢上賞
2015/11/25 - 公益財団法人アステラス病態代謝研究会公益財団法人アステラス病態代謝研究会最優秀理事長賞
2015/03/28 - 日本化学会第32回日本化学会学術賞細菌感染症克服にむけた化学生物学研究

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Association Membership(s) (6)：

American Chemical Society , 日本NO学会 , 日本農芸化学会 , 有機合成化学協会 , 日本ケミカルバイオロジー学会 , 日本化学会

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