Research field (2)：
Immunology
, Medical biochemistry
Research keywords (2)：
医化学一般
, Medical Chemistry in General
Research theme for competitive and other funds (23)：
2017 - 2020 A novel mechanism to regulate chronic inflammation through metabolic remodeling in obesity and senescence
2014 - 2017 Signaling mechanisms of chronic inflammation and metabolic diseases
2011 - 2013 肥満による慢性炎症性病変の新規制御機構の解析
2008 - 2010 MAPキナーゼによる炎症制御ネットワークの解析
2004 - 2004 変異導入マウスによるMAPキナーゼ経路の機能解析
2003 - 2004 Analysis of ERK2 roles in immunoregulation by ERK2 mutant mice
2003 - 2003 変異導入マウスによるMAPキナーゼ経路の分割化と機能解析
2001 - 2002 Analysis of MAP kinase cascade in the immune response
2001 - 2002 免疫系におけるMAPキナーゼ抑制機構の生理機能
2000 - 2000 チロシン脱リン酸化酵素群によるMAPキナーゼの直接抑制機構
2000 - 2000 免疫細胞におけるMAPキナーゼの新規抑制機構
1999 - 2000 Regulation of MAP Kinases by LC-PTP in hematopoietic cells
1999 - 1999 チロシンホスファターゼ相同性分子による細胞接着、細胞骨格の制御機構
1994 - 1999 サイトカインによる担癌宿主T細胞の応答制御
1998 - 1998 細胞接着を介したチロシンホスファターゼ相同性分子のシグナル伝達機構
1997 - 1997 細胞質型チロシンホスファターゼの細胞外シグナルによる制御機構
1996 - 1997 Regulation of a cytoplasmic protein tyrosine phosphatase through cell-substrate adhesion
1996 - 1996 細胞質型チロシンホスファターゼの細胞外シグナルによる制御機構
1993 - 1994 Cloning and analysis of protein tyrosine phosphatases expressed in lymphoid organs.
チロシン脱リン酸化酵素によるMAPキナーゼの制御
チロシン リン酸化・脱リン酸化によるリンパ球の分化と機能の制御
Regulation of MAP kinase by tyrosine phosphatases
Regulation of lymphocyte development and function by tyrosine phosphorylation /dephosphorylation.
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Papers (11)：
Naoki Kato, Masahito Matsumoto, Masakazu Kogawa, Gerald J. Atkins, David M. Findlay, Takahiko Fujikawa, Hiromi Oda, Masato Ogata. Critical role of p38 MAPK for regeneration of the sciatic nerve following crush injury in vivo. JOURNAL OF NEUROINFLAMMATION. 2013. 10
Takahiko Fujikawa, Tetsuya Hirata, Shingo Hosoo, Kenji Nakajima, Atsunori Wada, Yutaka Yurugi, Hideaki Soya, Takashi Matsui, Akihiko Yamaguchi, Masato Ogata, et al. Asperuloside stimulates metabolic function in rats across several organs under high-fat diet conditions, acting like the major ingredient of eucommia leaves with anti-obesity activity. Journal of Nutritional Science. 2012. 1. 1-11
Tomoko Fukumi-Tominaga, Yoshiko Mori, Atsuko Matsuura, Keiko Kaneko, Makoto Matsui, Masato Ogata, Makoto Tominaga. DIP/WISH-deficient mice reveal Dia- and N-WASP-interacting protein as a regulator of cytoskeletal dynamics in embryonic fibroblasts. GENES TO CELLS. 2009. 14. 10. 1197-1207
Yuka Okada, Yuko Ueshin, Ayako Isotani, Tomoko Saito-Fujita, Hisako Nakashima, Kazushi Kimura, Akira Mizoguchi, Masatsugu Oh-hora, Yoshiko Mori, Masato Ogata, et al. Complementation of placental defects and embryonic lethality by trophoblast-specific lentiviral gene transfer. NATURE BIOTECHNOLOGY. 2007. 25. 2. 233-237
Takahiko Fujikawa, Kenji Tamura, Tomoko Kawase, Yoshiko Mori, Randall R Sakai, Kunihiro Sakuma, Akihiko Yamaguch, Masato Ogata, Hideaki Soya, Kunio Nakashima. Prolactin receptor knockdown in the rat paraventricular nucleus by a morpholino-antisense oligonucleotide causes hypocalcemia and stress gastric erosion. Endocrinology. 2005. 146. 8. 3471-80
T Fujikawa, S Miguchi, N Kanada, N Nakai, M Ogata, Suzuki, I, K Nakashima. Acanthopanax senticosus Harms as a prophylactic for MPTP-induced Parkinson's disease in rats. JOURNAL OF ETHNOPHARMACOLOGY. 2005. 97. 2. 375-381
M Ogata, Y Mori. MAP kinase and its regulation through protein tyrosine phosphatases. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2004. 94. 15P-15P
