Rchr

J-GLOBAL ID：200901011102908660 Update date: Nov. 20, 2024

Imaoka Tatsuhiko

Imaoka Tatsuhiko | Imaoka Tatsuhiko

Affiliation and department：
Job title： Director
Homepage URL (2)： https://www.nirs.qst.go.jp/usr/radeff/ , https://www.nirs.qst.go.jp/usr/radeff/en/

Research field (7)： Hygiene and public health (laboratory) , Radiology , Tumor biology , Nanobioscience , Environmental effects of radiation , Developmental biology , Morphology, anatomy

Research keywords (7)： biology for radiological protection , application of quantum technologies to biomedical research , radiation carcinogenesis , breast cancer and mammary gland biology , tissue stem cells and cell-of-origin of cancer , mutational signatures in the cancer genome , development and homeostasis

Research theme for competitive and other funds (20)：

2020 - 2030 量子生命技術の創製と医学・生命科学の革新
2021 - 2025 Genetic susceptibility to radiation-induced breast cancer: establishment of an animal model for developing prevention strategy
2019 - 2024 放射線が細胞競合に及ぼす影響をラット乳腺培養系で評価する
2019 - 2022 動物モデルと数理モデルを用いた放射線発がん線量率効果が生じるメカニズムの解明
2015 - 2020 Development of rat models as a component technology for visualizing the process of radiation-induced carcinogenesis

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Papers (81)：

Atsuko Ishikawa, Yoshika Kin, Yutaka Yamada, Takamitsu Morioka, Mayumi Nishimura, Tatsuhiko Imaoka, Shizuko Kakinuma, Satoshi Tanaka, Rei Nakahira, Etsuko Kobayashi, et al. Sharing of data archive of radiation exposure animal experiments in QST/NIRS and IES. Radiation protection dosimetry. 2024. 200. 16-18. 1651-1655
Yukiko Nishimura, Daisuke Iizuka, Masaru Takabatake, Kazuhiro Daino, Mayumi Nishimura, Takamitsu Morioka, Yoshiya Shimada, Shizuko Kakinuma, Tatsuhiko Imaoka. Characterization of Molecular Subtypes of Rat Mammary Cancer and Their Association With Environmental Exposures. Anticancer Research. 2024. 44. 10. 4261-4272
Tatsuhiko Imaoka, Satoshi Tanaka, Masanori Tomita, Kazutaka Doi, Megumi Sasatani, Keiji Suzuki, Yutaka Yamada, Shizuko Kakinuma, Michiaki Kai. Human-mouse comparison of the multistage nature of radiation carcinogenesis in a mathematical model. International journal of cancer. 2024. 155. 6. 1101-1111
Kento Nagata, Mayumi Nishimura, Kazuhiro Daino, Yukiko Nishimura, Yuya Hattori, Ritsuko Watanabe, Daisuke Iizuka, Akinari Yokoya, Keiji Suzuki, Shizuko Kakinuma, et al. Luminal progenitor and mature cells are more susceptible than basal cells to radiation-induced DNA double-strand breaks in rat mammary tissue. Journal of Radiation Research. 2024. 65. 5. 640-650
Kentaro Ariyoshi, Tatsuhiko Imaoka, Yasushi Ohmachi, Yuka Ishida, Masahiro Uda, Mayumi Nishimura, Mayumi Shinagawa, Midori Yoshida, Toshiaki Ogiu, Mutsumi Kaminishi, et al. Influence of Age on Leukemia Mortality Associated with Exposure to γ rays and 2-MeV Fast Neutrons in Male C3H Mice. Radiation research. 2024. 202. 4. 685-696

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MISC (128)：

井沢玄佳, 井沢玄佳, 小川真里, 品川まゆみ, 鶴岡千鶴, SHANG Yi, 砂押正章, 橘拓孝, 森岡孝満, 柿沼志津子, et al. Cellular senescence as a possible mechanism of radiation-induced breast cancer. アイソトープ・放射線研究発表会(Web). 2023. 60th
中村柚月, 中村柚月, 臺野和広, 石川敦子, 柿沼志津子, 高畠賢, 高畠賢, 井上一雅, 今岡達彦, 今岡達彦. Brca1変異ラットを用いた放射線関連乳がんのBrca1正常アリル不活性化の検証. がん予防学術大会プログラム・抄録集. 2023. 2023
臺野和広, 渡辺光, 石川敦子, 高畠賢, 高畠賢, 今岡達彦, 今岡達彦, 柿沼志津子. Chromosome rearrangements in radiation-induced tumors. Journal of Toxicological Sciences. 2023. 48. Supplement (CD-ROM)
永田健斗, 西村まゆみ, 臺野和広, 臺野和広, 飯塚大輔, 飯塚大輔, 西村由希子, 西村由希子, 服部佑哉, 渡邊立子, et al. Analysis of early cellular dynamics leading to radiation carcinogenesis in rat mammary gland. 日本癌学会学術総会抄録集(Web). 2023. 82nd
西村由希子, 神長輝一, 宇佐美徳子, 横谷明徳, 今岡達彦. Does sparse radiation exposure affect rat mammary cell competition?. KEK Progress Report (Web). 2023. 2023-2

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Books (4)：

Combined Effect of Ionizing Radiation and N-Ethyl-N-Nitrosourea on Mutation Induction and Lymphoma Development
SPRINGER 2009
Effect of carbon ions on life span shortening and tumorigenesis in mice.
2004
Loss of heterozygosity in heavy-ion-induced murine T-cell lymphomas.
2003
Local function of prolactin.

Works (14)：

財団法人武田科学振興財団生命科学研究奨励「発がん標的としての組織幹細胞のDNA損傷応答に関する研究」
2009 - 2010
文部科学省原子力基礎基盤戦略研究イニシアティブ若手原子力研究プログラム「放射線発がんの非遺伝子変異的過程の解明」
2009 - 2010
Young Scientists Nuclear Energy Research Program, Nuclear Energy Fundamental Strategic Research Initiative (personal translation) from MEXT
2009 - 2010
Grant from the Takeda Science Foundation
2009 - 2010
文部科学省科学研究費補助金若手研究(B)「新規遺伝子の機能解析による放射線特異的な乳癌誘発メカニズムの解明」
2008 - 2010

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Education (4)：

1997 - 2002 The University of Tokyo Graduate School of Science Department of Biological Sciences
1995 - 1997 The University of Tokyo School of Science Zoology
1993 - 1995 The University of Tokyo College of Arts and Sciences Natural Sciences I
1990 - 1993 Azabu High School

Professional career (1)：

Ph.D. (The University of Tokyo)

Work history (31)：

2024/07 - 現在 National Institutes for Quantum Science and Technology Department of Radiation Effects Research, Institute for Radiological Science Director
2024/04 - 現在 National Institutes for Quantum Science and Technology Quantum Cancer Science Team, Quantum Life Sensing Group, Institute for Quantum Life Science Team Leader
2024/04 - 現在 National Institutes for Quantum Science and Technology Research Promotion Office, Institute for Radiological Science
2024/04 - 現在 National Institutes for Quantum Science and Technology Biomarker Research Group, Department of Radiation Effects Research, Institute for Radiological Science Group Leader
2020/04 - 現在 Tokyo Metropolitan University

2023/04 - 2024/03 National Institutes for Quantum Science and Technology Radiological Sciences Promotion Group, Department of Research Planning and Promotion, Quantum Life and Medical Science Directorate Group Leader

2023/04 - 2024/03 National Institutes for Quantum Science and Technology Biomarker Research Group, Department of Radiation Effects Research, Institute for Radiological Science, Quantum Life and Medical Science Directorate Group Leader

2023/04 - 2024/03 National Institutes for Quantum Science and Technology Risk Model Research Group, Department of Radiation Effects Research, Institute for Radiological Science, Wuantum Life and Medical Science Directorate Group Leader

2022/04 - 2024/03 National Institutes for Quantum Science and Technology Quantum Cancer Science Team, Institute for Quantum Life Science, Quantum Life and Medical Science Directorate Team Leader

2022/04 - 2023/03 National Institutes for Quantum Science and Technology Radiobiology for Children's Health Research Group, Department of Radiation Effects Research, National Institute of Radiological Sciences, Quantum Life and Medical Science Directorate Group Leader

2021/04 - 2023/03 National Institutes for Quantum Science and Technology Quantum Life Science Promotion Group, Department of Research Planning and Promotion, Quantum Life and Medical Science Directorate

2021/04 - 2023/03 National Institutes for Quantum Science and Technology Stem Cells and Effect Modifiers Research Group, Department of Radiation Effects Research, National Institute of Radiological Sciences, Quantum Life and Medical Science Directorate Group Leader

2022/04 - 2022/06 National Institutes for Quantum Science and Technology Carcinogenesis Dynamics Research Group, Department of Radiation Effects Research, National Institute of Radiological Sciences, Quantum Life and Medical Science Directorate Group Leader

2021/04 - 2022/03 National Institutes for Quantum and Radiological Science and Technology Institute for Quantum Life Science, Quantum Life and Medical Science Directorate Senior Group Leader

2021/04 - 2022/03 National Institutes for Quantum Science and Technology Quantum Cancer Science Group, Institute for Quantum Life Science, Quantum Life and Medical Science Directorate Group Leader

2019/04 - 2022/03 National Institutes for Quantum and Radiological Science and Technology Quantum Biosensors in Wide Bandgap Semiconductors Research Group

2020/07 - 2021/03 National Institutes for Quantum and Radiological Science and Technology Institute for Quantum Life Science Senior Group Leader

2019/04 - 2021/03 National Institutes for Quantum and Radiological Science and Technology Research Planning and Promotion Group, Institute for Quantum Life Science

2019/04 - 2021/03 National Institutes for Quantum and Radiological Science and Technology Quantum Cancer Science Group, Institute for Quantum Life Science Group Leader

2019/04 - 2021/03 National Institutes for Quantum and Radiological Science and Technology Stem Cells and Cancer Research Group, Department of Radiation Effects Research, National Institute of Radiological Sciences, Quantum Medical Science Directorate Group Leader

2017/04 - 2020/03 Tokyo Metropolitan University Visiting Professor

2017/08 - 2019/03 National Institutes for Quantum and Radiological Science and Technology Quantum State-Controlled MRI Group, QST Advanced Study Laboratory

2016/09 - 2019/03 National Institutes for Quantum and Radiological Science and Technology Quantum and Cellular Systems Biology Group, QST Advanced Study Laboratory

2016/04 - 2019/03 National Institutes for Quantum and Radiological Science and Technology Stem Cells and Cancer Research Team, Department of Radiation Effects Research, National Institute of Radiological Sciences Team Leader

2012/04 - 2017/03 Tokyo Metropolitan University Visiting Associate Professor

2012/05 - 2016/03 National Institute of Radiological Sciences Radiation Effect Accumulation and Prevention Project, Fukushima Project Headquarters

2011/04 - 2016/03 National Institute of Radiological Sciences Radiobiology Research Team, Radiobiology for Children's Health Program, Research Center for Radiation Protection Team Leader

2008/07 - 2011/03 National Institute of Radiological Sciences Experimental Radiobiology for Children’s Health Research Group, Research Center for Radiation Protection Senior Researcher

2006/04 - 2008/06 National Institute of Radiological Sciences Experimental Radiobiology for Children’s Health Research Group, Research Center for Radiation Protection Researcher

2002/04 - 2006/03 National Institute of Radiological Sciences Low Dose Radiation Effects Research Project 2nd Team, Research Center for Radiation Safety Researcher

2000/08 - 2001/08 University of Cincinnati School of Medicine Department of Molecular and Cellular Physiology Visiting Scientist

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Committee career (27)：

2024/06 - 現在 Japanese Radiation Research Society Vice President, Councilor, Chair of Scientific Committee, Chair of Prize Selection Committee, Finaice Committee member, Radiation Accident and Disaster Committee member
2023/07 - 現在 Radiation Effects Research Foundation Scientific Advisory Committee member
2020/01 - 現在 Journal of Radiation Research Associate Editor
2020 - 現在 Institute for Environmental Sciences [Research Evaluation Committee]
2019/01 - 現在 International Commission on Radiological Protection (ICRP) Task Group 111 Corresponding Member

2022/07 - 2024/06 Japanese Radiation Research Society Member of Finance Committee, Member of Academic Committee, Member of Prize Selection Committee

2022/06 - 2024/06 Japanese Radiation Research Society Executive Director (Vice President), Councilor, Chair of Globalization Committee

2020/06 - 2022/06 Japanese Radiation Research Society Executive Director, Councilor, Chair of Awards Committee, Chair of Academic Committee, Member of Financial Committee

2016/04 - 2021/03 広島大学放射線災害・医科学研究拠点共同研究課題審査部会委員

2014/06 - 2021/03 公益財団法人環境科学技術研究所低線量放射線影響実験調査委員会委員

2018/06 - 2020/06 一般社団法人日本放射線影響学会常任理事・学術評議員・賞等選考委員会委員長・学術委員会委員長・財務委員会委員・低線量小委員会委員

2016/04 - 2020/05 Chiba Prefectural Government Member of Bio- and Life Science Network Administration Committee

2018/04 - 2020/03 京都大学生命科学研究科放射線生物研究センター運営委員

2016/04 - 2020/03 Chiba Municipal Government Science City Strategy Committee (member)

2018/04 - 2019/03 文部科学省科学技術・学術政策研究所科学技術予測センター平成30年度専門調査員

2017/04 - 2019/03 京都大学放射線生物研究センター共同利用専門委員会委員

2017/04 - 2019/03 量子生命科学研究会運営委員

2019 - 日本放射線影響学会第62回大会プログラム委員

2016/06 - 2018/06 Japanese Radiation Research Society Councilor, Secretary, Member of Awards Committee

2013 - 2015 Journal of Radiation Research Associate Editor

2010/06 - 2014/06 Councilor

2010/04 - 2012/03 Radiation Effects Association International Radiation Epidemiology Information Investigation Committee

2009/01 - 2009/12 Young Radiation Biologists' Association of Japan President

2008/01 - 2009/12 Japanese Radiation Research Society Member of Future Planning Committee

2007/04 - 2009/03 千葉県市川市湊育成会理事

2008/01 - 2008/12 Young Radiation Biologists' Association of Japan Vice President

2007/07 - 2008/06 National Personnel Authority National Public Officers Examination (I) Technical Committee (Biotechnology)

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Awards (7)：

2023/07 - National Institutes for Quantum Science and Technology President's Commendation (R&D Achievement Award) Animal Model of Susceptibility to Environmental Carcinogenesis
2010/07 - 独立行政法人放射線医学総合研究所平成22年度特別表彰
2010/03 - Radiation Effects Association, Japan The 4th Radiation Effects Research Incentive Award Research on evaluation of radiation effects and elucidation of radiation carcinogenesis mechanisms that contribute to the refinement of radiation protection
2009/07 - National Institute of Radiological Sciences Special Commendation of National Institute of Radiological Sciences
2008/11 - Japanese Radiation Research Society Young Investigator Award

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Association Membership(s) (5)：

Japan Society for Biomedical Gerontology , Japan Health Physics Society , Quantum Life Science Society , The Japanese Cancer Association , Japanese Radiation Research Society

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