Rchr
J-GLOBAL ID：200901011378969433
Update date: Apr. 29, 2024
Kondoh Masuo
Kondoh Masuo
Affiliation and department：
Job title：
Professor
Homepage URL (1)：
https://masuo0.wixsite.com/rsphsosakauniv
Research field (2)：
Pharmaceuticals - health and biochemistry
, Clinical pharmacy
Research theme for competitive and other funds (24)：
- 2022 - 2025 脳部位特異性を有する次世代脳内薬物送達システムの開発
- 2020 - 2024 Development of the integrated therapeutic strategy aiming toward drug discovery and pharmacotherapy for treatment-resistant schizophrenia
- 2022 - 2024 医療機器の情報共有による患者中心の医療イノベーションに関する研究
- 2022 - 2023 患者フレンドリーな次世代経皮薬物送達技術の開発
- 2019 - 2022 低分子・高分子・ナノ医薬品の脳部位特異的送達システムの開発
- 2018 - 2020 血液脳関門シールド制御による脳内薬物送達技術の開発への挑戦
- 2015 - 2018 A novel tricellular tight junction molecule LSR in diagnosis and therapy for cancer
- 2014 - 2017 Studies on molecular mechanism of paracellular pathway
- 2013 - 2016 Strategic approach based on molecular mechanism for modulation of barrier function of tight junction to enhance delivery of new biopharmaceuticals
- 2012 - 2015 Claudin-1 as a target for modulation of epidermal barriers
- 2011 - 2012 Development ofan assay system for hepatitis C virus in mice
- 2009 - 2012 Development of non-invasive drug delivery system using claudin modulator
- 2009 - 2011 Studies of barrier function of tight junction in epithelial celllayers and strategic development of novel methods for drug permeation enhancement in cells
- 2008 - 2009 RNAポリメラーゼI発現系を利用したC型肝炎ウイルス増幅系の開発
- 2007 - 2008 A Novel Strategy for Enhancement of Permeation and Absorption of Drugs by Modulation of Proteins Constructed Barrier Function in Biomembrane
- 2006 - 2007 Claudin modulatorを利用した新規薬物送達方法の構築
- 2005 - 2006 Studies on Drug Permeation in Placental Barrier by RNA Interference
- 2002 - 2005 Role of metallothionein against toxicity of reactive oxygen species induced mitochondria
- 2003 - 2004 Development of Gene Transfer Systems into Placental Cells for Studies of Drug Transport Mechanism in Blood-Placenta Barrier
- 2003 - 2004 タイトジャンクション構成分子Claudinを標的とした新規吸収促進戦略の確立
- 2001 - 2002 小胞体ストレスに対するメタロチオネインの誘導および防御作用
- 2000 - 2001 メタロチオネインのストレス系細胞内シグナル伝達調節機構
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Papers (192)：
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Keisuke Tachibana, Ryuichi Hirayama, Naoyuki Sato, Kotaro Hattori, Takashi Kato, Hiroyuki Takeda, Masuo Kondoh. Association of Plasma Claudin-5 with Age and Alzheimer Disease. International journal of molecular sciences. 2024. 25. 3
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Rina Fujiwara-Tani, Shiori Mori, Ruiko Ogata, Rika Sasaki, Ayaka Ikemoto, Shingo Kishi, Masuo Kondoh, Hiroki Kuniyasu. Claudin-4: A New Molecular Target for Epithelial Cancer Therapy. International journal of molecular sciences. 2023. 24. 6
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Koji Hosomi, Atsushi Shimoyama, Atsushi Hinenoya, Noritoshi Hatanaka, Takafumi Noguchi, Hirotaka Ebina, Yoko Tojima, Mari Furuta, Masuo Kondoh, Hiroshi Kiyono, et al. Endotoxin-Free Stx2B-C-CPE Vaccine and Its Optimized Adjuvant Regimen for Preventing Food Poisoning. Frontiers in Bioscience-Landmark. 2023. 28. 1. 15-15
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Yoshitaka Shirasago, Hidesuke Fukazawa, Shotaro Nagase, Yoshimi Shimizu, Tomoharu Mizukami, Takaji Wakita, Tetsuro Suzuki, Hideki Tani, Masuo Kondoh, Takuya Kuroda, et al. A single mutation in the E2 glycoprotein of hepatitis C virus broadens the claudin specificity for its infection. Scientific reports. 2022. 12. 1. 20243-20243
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Lin Bai, Keisuke Tachibana, Michika Murata, Tetsunori Inoue, Hiroyuki Mizuguchi, Shinichiro Maeda, Kenji Ikemura, Masahiro Okuda, Tetsuya Kusakabe, Masuo Kondoh. A doxycycline-inducible CYP3A4-Caco-2 cell line as a model for evaluating safety of aflatoxin B1 in the human intestine. Toxicology letters. 2022. 370. 1-6
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MISC (221)：
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村岡康介, 白倉圭佑, 船津梨彩, 井上采人, 土井健史, 竹田浩之, 橘敬祐, 近藤昌夫, 藤尾慈, 岡田欣晃. Development of intracerebral drug delivery technology using Claudin-5 binding molecules. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
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安藤大介, 山本栄一, QUAN Ying-shu, 近藤昌夫, 岡田直貴, 伊豆津健一. A Review of the Manufacturing Methods and Quality Attributes for Microneedle Array Development. 医薬品医療機器レギュラトリーサイエンス. 2021. 52. 5
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松下俊介, 橘敬祐, 日下部哲也, 日下部哲也, 堤康央, 近藤昌夫. Regulatory Considerations of Conditional Approval for Balancing Pre-market and Post-market Evaluations to Achieve Early Patient Access to Medical Products in Japan. レギュラトリーサイエンス学会誌. 2021. 11. 2
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庄真喜子, 橘敬祐, 原田和生, 平田收正, 堤康央, 國澤純, 國澤純, 國澤純, 國澤純, 國澤純, et al. Current situation and challenges of a regulatory concept of pharmacokinetics focusing on microbiome. 腸内細菌学雑誌. 2021. 35. 2
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若山英里香, 橘敬祐, 竹田浩之, 近藤昌夫. Development of regulatory science platforms for the central nervous system. 日本薬学会年会要旨集(CD-ROM). 2020. 140th
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Patents (11)：
Books (1)：
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ペプチド・タンパク性医薬品の新規DDS製剤の開発と応用「第1章第5項 Claudin modulatorを用いたペプチド・タンパク性医薬品の経粘膜吸収促進」
メディカルドゥ 2011
Education (2)：
- - 1998 Osaka University
- - 1998 Osaka University Graduate School, Division of Pharmaceutical Sciences
Work history (9)：
- 2023/04 - 現在 Osaka University
- 2018/04 - 現在 Professor,Drug Innovation Center, Graduate School of Pharmaceutical Sciences, Osaka University
- 2015/04 - 2107/03 厚生労働省 医政局 研究開発振興課 臨床研究推進指導官
- 2017/04 - 2018/03 厚生労働省 医薬・生活衛生局 医療機器審査管理課 医療機器審査調整官
- 2012/04/01 - 2015/03/31 Osaka University Graduate School of Pharmaceutical Sciences Medical Pharmacy Associate Professor
- 2007/04 - 2015/03 Associate Professor, Graduate School of Pharmaceutical Sciences, Osaka University
- 2007/04/01 - 2012/03/31 Osaka University Graduate School of Pharmaceutical Sciences Molecular Pharamaceutical Sciences Associate Professor
- 2006/04/01 - 2007/03/31 Osaka University Graduate School of Pharmaceutical Sciences Molecular Pharamaceutical Sciences Associate Professor
- 2006/04 - 2007/03 Associate Professor, Graduate School of Pharmaceutical Sciences, Osaka University
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Awards (6)：
- 2019/07 - 日本DDS学会 第19回日本DDS学会永井賞
- 2011/08 - 国立大学法人 大阪大学 平成23年大阪大学功績賞
- 2010/02 - The German Chamber of Commerce and Industry in Japan German Innovation Award, Gottfried Wagener Prize 2009 Award 3rd prize
- 2009/07 - 日本DDS学会 日本DDS学会奨励賞
- 2009/05 - 社団法人 日本薬剤学会 日本薬剤学会奨励賞
- 2006 - 日本薬学会奨励賞
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Association Membership(s) (1)：
American Society for Pharmacology & Experimental Therapeutics
