Rchr

J-GLOBAL ID：200901011497626226 Update date: Sep. 19, 2024

Okuda Kiyoshi

オクダキヨシ | Okuda Kiyoshi

Affiliation and department：
Job title： Executive Advisor

Research field (2)： Veterinary medicine , Animal production science

Research keywords (18)：アポトーシス , プロスタグランディン , サイトカイン , ホルモン , 妊娠 , 黄体 , 子宮 , 卵巣 , 生殖内分泌学 , Apoptosis , Prostaglandin , Cytokine , Hormone , Pregnancy , Uterus , Corpus luteum , Ovary , Reproductive Endocrinology

Research theme for competitive and other funds (36)：

2014 - 2018 Evaluation method for quality the farm animal egg: Based on the molecular mechanism of follicle selection
2015 - 2017 Activin A as a coordinator of oviductal environment: local action for successful fertilization and establishment of pregnancy in oviducts
2015 - 2017 Regulatory mechanism of coordinated beating of oviductal cilia
2014 - 2017 Role of glycosphingolipids and galectins in the regulation of the corpus luteum function
2014 - 2016 ウマ子宮内膜における異種細胞間の相互機能調節に関する研究

2012 - 2016 Regulatory mechanism of ovarian and endometrial functions controlling the reproductive cycle

2013 - 2015 Study on the mechanisms of corpus luteum disappearance during luteolysis

2010 - 2014 Creation of judging method for livestock egg quality based on the molecular mechanism of follicular selection

2013 - ウシ卵管の機能調節機構に関する研究

2013 - Study on oviductal function in cattle

2008 - 2009 ウシ胚発生能に及ぼすグルココルチコイドの影響とネコ子宮内膜の機能調節に関する研究

2007 - 2009 Clarification of the mechanism controlling the regression of corpus luteum by reactive oxygen species

2006 - 2009 Development of estimation method for mammalian oocyte quality based on molecular mechanism of follicular selection

2006 - 2008 Study on the network in ovary-uterus-immune systems in regulating ovulation cycle

2006 - 2007 低酸素誘導性転写因子(Hif-1)の発現調節による抗血管新生療法の開発

2005 - 2006 INTERACTION AMONG SEVERAL TYPES OF LUTEAL CELLS DURING SPONTANEOUS AND INDUCED LUTEOLYSIS

2004 - 2005 Roles of glucocorticoid in female reproduction

2002 - 2004 Crosstalk between immune cells and corpus luteum cells in regulating luteolysis and its application for animal reproduction

2002 - 2003 血管内皮細胞のアポトーシス誘導による抗血管新生療法の開発

2002 - 2003 インターロイキン18の生殖内分泌系における新しい作用の解析

2001 - 2003 Molecular and cellular analysis of autocrine and paracrine functions of endometrial growth factors

2001 - 2003 内分泌攪乱物質による生殖毒性評価システムの構築:構造生物学・細胞生物学的リアルタイム評価法の確立

2000 - 2002 Development of Technology for Regulating Reproductive Efficiency by Controlling Corpus Luteum Function in Cows

1999 - 2001 Development of an efficient methods of calf reproduction by embryo transfer in combination with treatment of interferon-_τ

1999 - 2001 Multi-dimensional analyses of local regulatory mechanisms in bovine ovary

1999 - 2000 哺乳動物の生殖細胞を用いた内分泌撹乱化学物質の評価法の確立

1996 - 1998 Studies on the development of a system for effective calf production by in-vitro fertilization

1998 - ウシ子宮内膜の機能調節機構に関する研究

1998 - Study on the function of bovine endometrium in the estrous cycle

1996 - 1996 ウシ顆粒層細胞の分化に伴うPGF2αレセプター発現調節機構の解明

1994 - 1994 Transgenic animal production for mammary gland manipulation

1993 - 1994 Studies on the regulation of oxytocin receptor in bovine corpus luteum

1989 - 1991 Fundamental Studies on Nuclear Transplantation in Early Mammalian Embryos

1989 - 1991 Studies on the development of production technique of agriculture and animal husbandry in Inner Mongolia

1986 - ウシ黄体の機能調節機構に関する研究

1986 - Study on the regulation of bovine corpus luteum in the estrous cycle

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Papers (238)：

Takuo HOJO, Dariusz J. SKARZYNSKI, Kiyoshi OKUDA. Apoptosis, autophagic cell death, and necroptosis: different types of programmed cell death in bovine corpus luteum regression. Journal of Reproduction and Development. 2022. 68. 6. 355-360
Szóstek-Mioduchowska A, Shiotani H, Yamamoto Y, Sadowska A, Wójtowicz A, Kozai K, Hojo T, Kimura K, Skarzynski DJ, Okuda K. Effects of cortisol on prostaglandin F2α secretion and expression of genes involved in the arachidonic acid metabolic pathway in equine endometrium - in vitro study. Theriogenology. 2021. 173. 10. 221-229
Shunsuke Sakai, Mami Yagi, Nao Fujime, Mariko Kuse, Ryosuke Sakumoto, Yuki Yamamoto, Kiyoshi Okuda, Koji Kimura. Heat stress influences the attenuation of prostaglandin synthesis by interferon tau in bovine endometrial cells. Theriogenology. 2021. 165. 1-7
Yuki Yamamoto, Sayaka Ito, Kiyoshi Okuda, Koji Kimura. Involvement of activin signal pathway in cyclic apoptosis of the oviductal isthmic epithelium in cows. Theriogenology. 2020. 153. 143-150
Ryo Nishimura, Kiyoshi Okuda. Multiple roles of hypoxia in bovine corpus luteum. Journal of Reproduction and Development. 2020. 66. 307-310

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MISC (138)：

OKUDA Kiyoshi. The present and future in an agricultural and animal science college in regional area. 2021. 627. 4-7
Kiyoshi OKUDA. The Education of Agriculture in National University. JOURNAL OF THE AGRICULTURE. 2020. 1660. 1. 19-20
PGF2α auto-amplification system in the endometrium in the mare. Equine science. 2019. 56. 4. 282-293
長谷川啓喜, 山下真路, 伊藤典彦, 岡本芳晴, 窪友瑛, 伊賀浩輔, 木村康二, 菱沼貢, 奥田潔, 西村亮, et al. ウシ黄体におけるbetaglycanの役割とその発現調節. 日本畜産学会大会講演要旨. 2018. 124th. 205
長谷川啓喜, 西村亮, 菱沼貢, 山下真路, 伊藤典彦, 岡本芳晴, 窪友瑛, 伊賀浩輔, 木村康二, 奥田潔. ウシ初期および中期黄体細胞のプロジェステロン(P4)分泌に及ぼす低酸素環境の影響. 日本畜産学会大会講演要旨集. 2017. 122回. 160-160

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Books (17)：

畜産学
養賢堂 2022 ISBN:9784842505831
繁殖生物学改訂版
インターズ(東京) 2020
The Life Cycle of the Corpus Luteum
Springer 2017
THE LIFE CYCLE OF THE CORPUS LUTEUM
Springer Publishing Company, New York 2017
繁殖生物学
インターズー、東京 2013

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Lectures and oral presentations (260)：

Gene expression in the corpus luteum (CL) of the estrous cycle and pregnancy: Possible roles of eotaxin (CCL11) and lymphotactin (XCL1) in regulating CL function during pregnancy
(第9回国際反すう動物生殖科学シンポジウム 2014)
The VEGF system supported by galectin-1 maintains the function of bovine corpus luteum
(第9回国際反すう動物生殖科学シンポジウム 2014)
Interaction between nitric oxide and endothelin-1 in bovine oviduct
(第9回国際反すう動物生殖科学シンポジウム 2014)
Galectin-3 participates in luteolysis by binding to b1 integrin in the bovine corpus luteum
(第9回国際反すう動物生殖科学シンポジウム 2014)
The role of autophagy in regression of bovine corpus luteum in relation to lysosomal function.
(第107回日本繁殖生物学会大会 2014)

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Works (76)：

排卵周期を支配する卵巣と子宮の機能調節機構の解明
2012 - 2016
哺乳動物の黄体組織消滅機構の解明
2013 - 2015
卵胞選抜の分子に基づく家畜卵子の品質判定法の創出
2010 - 2014
ウシ胚発生に及ぼすグルココルチコイドの影響とネコ子宮内膜の機能調節に関する研究
2008 - 2009
低酸素誘導性転写因子(Hif-1)の発現調節による抗血管新生療法の開発
2006 - 2009

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Education (3)：

1979 - 1982 University of Munich
1979 - 1982 Ludwig-Maximilians Universität München (LMU München) Graduate School of Veterinary Medicine
1977 - 1979 Obihiro University of Agriculture and Veterinary Medicine Graduate School of Veterinary Science Division of Veterinary Medicine

Professional career (2)：

Doctor medicinae veterinariae (University of Munich)
Dr. of Agriculture (Kyoto University)

Work history (19)：

2022/04 - 現在 Obihiro University of Agriculture and Veterinary Medicine Executive Advisor
2017/12 - 現在 Polish Academy of Science foreign member of Polish Academy of Science
2016/01 - 2022/03 Obihiro University of Agriculture and Veterinary Medicine President
2012/04 - 2016/12 Okayama University The Graduate School of Environmental and Life Science Professor
2010/09 - 2016/03 Kobe University Faculty of Agriculture Visiting lecturer

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Committee career (19)：

2022/02 - 現在国立研究開発法人農業・食品産業総合研究機構評価委員
2019/07 - 2021/06 国立大学協会理事
2015 - 2019 日本繁殖生物学会外部受賞専門委員会委員長
2016/04 - 2017/03 内閣府食品安全委員会動物用医薬品専門調査会専門参考人
2012/04 - 2016/03 日本生殖内分泌学会評議員

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Awards (3)：

2001 - 森永奉仕会賞
2001 - Award for Outstanding Research in Dairy Cow (Morinaga)
1997 - 日本繁殖生物学会(佐藤)賞

Association Membership(s) (12)：

岡山県産業動物獣医学会 , 米国繁殖学会 , おかやまバイオアクティブ研究会 , 関西畜産学会 , 英国繁殖学会 , 日本比較内分泌学会 , 日本畜産学会 , 日本獣医学会 , 日本繁殖生物学会 , Society for the Study of Reproduction , Society for the Study of Fertility , Japan Society of Reproductive Endocrinology

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