Rchr
J-GLOBAL ID:200901011535093709   Update date: Jan. 30, 2024

Sato Hironori

サトウ ヒロノリ | Sato Hironori
Affiliation and department:
Job title: Principal Investigator
Research field  (1): Virology
Research keywords  (10): RNA virus ,  Emerging and re-emerging infectious diseases ,  Mutation ,  Structure ,  Function ,  replication ,  pathogenesis ,  persistent infection ,  epidemics ,  Evolution
Research theme for competitive and other funds  (12):
  • 2016 - 2019 HIV Gag 蛋白質の機能と進化能の構造生物学研究に基づく次世代の創薬シーズ創成
  • 2013 - 2016 HIV Gag 蛋白質と関連因子の治療標的構造の解明に向けた統合的研究
  • 2013 - 2014 RNA ウイルスの進化的脆弱性に関する研究
  • 2010 - 2013 HIV の構造、増殖、変異に関する研 究
  • 2007 - 2010 薬剤耐性 HIV の発生機序とその制御 方法に関する研究
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Papers (171):
  • Yoshihiro Samune, Akatsuki Saito, Tadahiro Sasaki, Ritsuko Koketsu, Narinee Srimark, Juthamas Phadungsombat, Masaru Yokoyama, Osamu Kotani, Hironori Sato, Atsushi Yamanaka, et al. Genetic regions affecting the replication and pathogenicity of dengue virus type 2. PLOS Neglected Tropical Diseases. 2024. 18. 1. e0011885-e0011885
  • Mai Izumida, Osamu Kotani, Hideki Hayashi, Chris Smith, Tsutomu Fukuda, Koushirou Suga, Masatomo Iwao, Fumito Ishibashi, Hironori Sato, Yoshinao Kubo. Unique Mode of Antiviral Action of a Marine Alkaloid against Ebola Virus and SARS-CoV-2. Viruses. 2022. 14. 4. 816-816
  • Christopher Sumner, Osamu Kotani, Shuohui Liu, Karin Musier-Forsyth, Hironori Sato, Akira Ono. Molecular Determinants in tRNA D-arm Required for Inhibition of HIV-1 Gag Membrane Binding. Journal of Molecular Biology. 2022. 434. 2. 167390-167390
  • Osamu Kotani, Yasushi Suzuki, Shinji Saito, Akira Ainai, Akira Ueno, Takuya Hemmi, Kaori Sano, Koshiro Tabata, Masaru Yokoyama, Tadaki Suzuki, et al. Structure-Guided Creation of an Anti-HA Stalk Antibody F11 Derivative That Neutralizes Both F11-Sensitive and -Resistant Influenza A(H1N1)pdm09 Viruses. Viruses. 2021. 13. 9. 1733-1733
  • Takaaki Koma, Masaru Yokoyama, Osamu Kotani, Naoya Doi, Nina Nakanishi, Hayato Okubo, Shun Adachi, Akio Adachi, Hironori Sato, Masako Nomaguchi. Species-Specific Valid Ternary Interactions of HIV-1 Env-gp120, CD4, and CCR5 as Revealed by an Adaptive Single-Amino Acid Substitution at the V3 Loop Tip. Journal of Virology. 2021. 95. 13
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MISC (54):
Patents (3):
  • 化合物又はその塩並びに医薬組成物及び抗HIV剤
  • ベンジルアミン化合物並びにその医薬組成物及び抗HIV剤
  • 感染性HIVゲノムをコードするDNA
Books (21):
  • 計算科学技術を用いたRNAウイルスの構造研究
    Pharm stage 2021
  • 感染症研究と計算科学の橋渡し:病原体の理解と制御に向けて
    日本防菌防黴学会誌 2020
  • 季節性インフルエンザウイルスの流行予測
    インフルエンザ(メディカルレビュー社) 2019
  • In silico分子間相互作用解析基盤の開発とウイルス研究への活用
    技術情報協会 2018
  • Highly mutable animal RNA viruses: adaptation and evolution. edited by Masako Nomaguchi and Akio Adachi
    Frontiers Media SA 2017
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Lectures and oral presentations  (25):
  • 感染症研究と計算科学の橋渡し:病原体の理解と制御に向けて
    (防菌防黴学会年次大会シンポジウム 2018)
  • 計算科学と下痢症ウイルス研究の橋渡し
    (ウイルス性下痢症研究会 特別講演 2018)
  • Challenge for bridging virology and computational science
    (DRP Seminar, NCI, NIH 2018)
  • A challenge for bridging virology and computational science
    (LMM Seminar, NIAID, NIH 2018)
  • ウイルス研究と計算科学の融合への挑戦
    (新学術領域研究班 「ウイルス感染現象における宿主細胞コンピテンシーの分子基盤」ワークショップ 2017)
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Education (3):
  • 1982 - 1987 The University of Tokyo Faculty of Science Graduate School of Arts and Sciences
  • 1980 - 1982 The University of Tokyo Faculty of Arts and Sciences Division of Basic Science
  • 1978 - 1980 The University of Tokyo
Professional career (1):
  • Doctor of Science (The University of Tokyo)
Work history (8):
  • 2019/04 - 現在 National Institute of Infectious Diseases Pathogen Genomics Center Senior Scientist
  • 2005/10 - 2019/03 National Institute of Infectious Diseases Pathogen Genomics Center Laboratory Chief
  • 2001/08 - 2005/09 National Institute of Infectious Diseases Division of Molecular Genetics Principal Investigator
  • 1997/04 - 2001/07 National Institute of Infectious Diseases AIDS Research Center, Senior Scientist
  • 1993/04 - 1997/03 National Institute of Infectious Diseases AIDS Research Center, Junior Scientist
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Committee career (14):
  • 2022/04 - 現在 Japan Agency for Medical Research and Development Program Officer
  • 2020/04 - 現在 Japan Agency for Medical Research and Development Program Officer
  • 2020/04 - 現在 Viruses Editorial Board Members
  • 2020 - 現在 The Japanese Society for Virology director
  • 2019 - 現在 Japan Agency for Medical Research and Development Program Officer (International Collaborative Research Program: Strategic International Collaborative Research Program (SICORP))
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Association Membership(s) (4):
Japanese Society of Tropical Medicine ,  The Molecular Biology Society of Japan ,  The Japanese Society for Virology ,  The Japanese Society for AIDS Research
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