J-GLOBAL ID:200901012598147805   Update date: Jun. 09, 2020

Saga Yumiko

サガ ユミコ | Saga Yumiko
Homepage URL  (1): http://www.nig.ac.jp/labs/ManDev/home-j.html
Research field  (1): Laboratory animal science
Research keywords  (2): Molecular Biology ,  Developmental Genetics
Research theme for competitive and other funds  (4):
  • 2005 - 2009 The mechanism of somite segmentation with periodic patterning
  • 2002 - 2006 Molecular bases underlying cardiogenesis and somitogenesis of mesodermal cells
  • 1999 - 2001 Developmental genetics involved in the mechanism of vertebrate somitogenesis
  • 1998 - 2000 Analysis of segmentation initiation during somitogenesis
Papers (122):
  • Kato Y, Iwamori T, Ninomiya Y, Kohda T, Miyashita J, Sato M, Saga Y. ELAVL2-directed RNA regulatory network drives the formation of quiescent primordial follicles. EMBO reports. 2019. 20. 12. e48251
  • Saba R, Kitajima K, Rainbow L, Engert S, Uemura M, Ishida H, Kokkinopoulos I, Shintani Y, Miyagawa S, Kanai Y, Kanai-Azuma M, Koopman P, Meno C, Kenny J, Lickert H, Saga Y, Suzuki K, Sawa Y, Yashiro K. Endocardium differentiation through Sox17 expression in endocardium precursor cells regulates heart development in mice. Scientific reports. 2019. 9. 1. 11953
  • Yuki Niimi, Atsuki Imai, Hitomi Nishimura, Kenya Yui, Ai Kikuchi, Hiroko Koike, Yumiko Saga, Atsushi Suzuki. Essential role of mouse Dead end1 in the maintenance of spermatogonia. Developmental biology. 2019. 445. 1. 103-112
  • Shimada R, Kiso M, Saga Y. ES-mediated chimera analysis revealed requirement of DDX6 for NANOS2 localization and function in mouse germ cells. Scientific reports. 2019. 9. 1. 515
  • Fujita Y, Tominaga T, Abe H, Kangawa Y, Fukushima N, Ueda O, Jishage KI, Kishi S, Murakami T, Saga Y, Kanwar YS, Nagai K, Doi T. An adjustment in BMP4 function represents a treatment for diabetic nephropathy and podocyte injury. Scientific reports. 2018. 8. 1. 13011
MISC (24):
Lectures and oral presentations  (181):
  • The roles of DDX6 in early mouse embryogenesis and progenitor cells
  • Germ cell specific conditional knockout without making mouse lines
    (The 15th Transgenic technology meeting 2019)
  • Essential role of the expression network between two RNA-binding proteins in the formation of sustainable primordial follicles
  • Egg or sperm:how germ cell sex is determined
  • Mechanism of sexual differentiation of mouse germ cells
    (Developmental Biology seminar series: Sloan Kettering Cancer Center 2018)
Education (3):
  • University of Tsukuba
  • University of Tsukuba
  • Doctoral Program in Biological Sciences, University of Tsukuba
Professional career (1):
  • Doctor of Science
Work history (12):
  • 2000 - : National Institute of Genetics.
  • 1997 - : National Institute of Health Sciences,
  • 1995 - : Banyu pharmaceutical research center. Lab head
  • 1992 - : Banyu pharmaceutical research center.
  • 1989 - : The Institute of physical
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Association Membership(s) (2):
The Molecular Biology Society of Japan ,  The Japanese Society of Developmental Biologists
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