Kashiwabara Shin-ichi

カシワバラシンイチ | Kashiwabara Shin-ichi

Affiliation and department：
Job title： Associate Professor

Research field (2)： Developmental biology , Applied molecular and cellular biology

Research keywords (5)： translational regulation , translation , post-transcriptional gene regulation , poly(A) tail , gametogenesis

Research theme for competitive and other funds (14)：

2021 - 2024 精子形成減数分裂期以降における完全な翻訳抑制と部分的な翻訳抑制の機構
2018 - 2021 哺乳動物精子形成後期に特徴的な翻訳遅延と脱アデニル化の機構
2013 - 2015 RNase H2 is essential for ribonucleotide excision repair during DNA replication
2011 - 2012 クロマトイドボディおよびmRNP構成因子の精子形成における役割
2010 - 2012 Translational regulation by Argonaute protein, MIWI, and poly(A)-binding proteins

Show all

Papers (60)：

Oyama, Kanako, Baba, Tadashi, Kashiwabara, Shin-Ichi. Functional characterization of testis-brain RNA-binding protein, TB-RBP/Translin, in translational regulation. Journal of Reproduction and Development. 2020
Kim, Jaehyun, Nakamura, Junnosuke, Hamada, Chiharu, Taketomi, Takumi, Yano, Sarasa, Okajima, Tomomi, Kashiwabara, Shin-Ichi, Baba, Tadashi, Sato, Ban, Chiba, Tomoki, et al. USP15 deubiquitinates TUT1 associated with RNA metabolism and maintains cerebellar homeostasis. Mol Cell Biol. 2020. 40. 21. e00098-20
Kokubu, Daichi, Ooba, Ryousuke, Abe, Yukiko, Ishizaki, Hana, Yoshida, Shigeki, Asano, Atsushi, Kashiwabara, Shin-Ichi, Miyazaki, Hitoshi. Angelica keiskei (Ashitaba) powder and its functional compound xanthoangelol prevent heat stress-induced impairment in sperm density and quality in mouse testes. Journal of Reproduction and Development. 2019. 65. 2. 139-146
Kashiwabara, Shin-Ichi, Tsuruta, Satsuki, Yamaoka, Yutaro, Oyama, Kanako, Iwazaki, Chieko, Baba, Tadashi. PAPOLB/TPAP regulates spermiogenesis independently of chromatoid body-associated factors. Journal of Reproduction and Development. 2018. 64. 1. 25-31
Masamichi Ishizuka, Eri Ohtsuka, Atsuto Inoue, Mirei Odaka, Hirotaka Ohshima, Norihisa Tamura, Kaoru Yoshida, Norihisa Sako, Tadashi Baba, Shin-ichi Kashiwabara, et al. Abnormal spermatogenesis and male infertility in testicular zinc finger protein Zfp318-knockout mice. DEVELOPMENT GROWTH & DIFFERENTIATION. 2016. 58. 7. 600-608

ｍore...

Books (4)：

Regulation of spermatogenesis by polyadenylation and deadenylation of mRNAs
蛋白質核酸酵素・共立出版 2009
半数体精細胞特異的遺伝子の発現制御
生化学 2005
精巣特異的ポリ(A)ポリメラーゼTPAPによる精子形態形成制御
日本疾患モデル学会誌 2004
精巣特異的ポリ(A)ポリメラーゼTPAPによる精子形態形成制御
日本疾患モデル学会誌 2004

Lectures and oral presentations (27)：

Testis-specific cytoplasmic poly(A)-binding protein PABPC6 is encoded by a retroposed gene in the mouse.
(第45回日本分子生物学会年会 2022)
RNA結合タンパク質TB-RBPの原始卵胞における機能解析
(第45回日本分子生物学会年会 2022)
hnRNPU represses translation of a reporter mRNA in a sequence-specific manner.
(第45回日本分子生物学会年会 2022)
Involvement of RNA-binding protein YBX2 in global translational repression during spermatogenesis
(第114回日本繁殖生物学会大会 2021)
Functional analysis of Y-box RNA-binding protein YBX2 during mouse spermatogenesis
(第43回日本分子生物学会年会 2020)

ｍore...

Education (2)：

- 1993 University of Tsukuba Graduate School, Division of Agriculture
- 1988 University of Tsukuba Second Cluster of College

Work history (8)：

2007/04 - 現在筑波大学大学院生命環境科学研究科准教授
2004/04 - 2007/03 筑波大学大学院生命環境科学研究科助教授
2003/04 - 2004/03 University of Tsukuba Institute of Applied Biochemistry
1999/05 - 2003/03 University of Tsukuba Institute of Applied Biochemistry
1998/04 - 1999/04 University of Tsukuba Institute of Applied Biochemistry

Show all

Committee career (1)：

2020/04 - 2022/03 筑波大学放射線管理委員会委員

Awards (3)：

2003 - 財団法人東京生化学研究会東京生化学研究会研究助成
2003 - 財団法人上原記念生命科学財団上原記念生命科学財団研究助成
2003 - 財団法人ノバルティス科学振興財団ノバルティス研究奨励助成

Association Membership(s) (4)：

THE SOCIETY FOR REPRODUCTION AND DEVELOPMENT , THE RNA SOCIETY OF JAPAN , The Molecular Biology Society of Japan , JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page