Rchr
J-GLOBAL ID:200901013735393106   Update date: Jan. 30, 2024

Mukai Takahiro

ムカイ タカヒロ | Mukai Takahiro
Affiliation and department:
Job title: Associate Professor
Research field  (3): Radiology ,  Pharmacology ,  Pharmaceuticals - analytical and physicochemistry
Research keywords  (9): DDS ,  Multimodality ,  Theranostics ,  内用放射線治療薬剤 ,  分子イメージング ,  放射性薬剤 ,  Pharmacokinetics ,  Radiopharmaceutical Chemistry ,  Nuclear Medicine
Research theme for competitive and other funds  (43):
  • 2022 - 2026 外部刺激に応答するがん標的セラノスティックナノデバイスの開発
  • 2019 - 2022 Development of radiolabeled probes enabling to detect reactive oxygen species separately in living body
  • 2018 - 2020 核医学・蛍光デュアルイメージングを可能とするトリファンクショナルキレートの開発
  • 2016 - 2019 がんのラジオセラノスティックスを達成するための自己組織化ナノデバイスの開発
  • 2015 - 2017 ヘパラナーゼを分子標的とする放射性ヨウ素標識薬剤の開発
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Papers (234):
  • Masayuki Munekane, Hinako Mori, Nao Takada, Kohei Sano, Toshihide Yamasaki, Toru Tanaka, Naoto Sasaki, Yoshiyuki Rikitake, Takahiro Mukai. Preparation and evaluation of 111In-labeled liposomes containing phosphatidylglycerol for detection of macrophages in atherosclerotic plaques. Nuclear medicine and biology. 2023. 126-127. 108388-108388
  • Yoshie Haratake, Kohei Sano, Chika Fujioka, Satsuki Oshima, Masayuki Munekane, Toshihide Yamasaki, Takahiro Mukai. Chemical design of radioiodinated probes with a metabolizable linkage for target-selective imaging of systemic amyloidosis. Bioorganic & medicinal chemistry. 2023. 92. 117426-117426
  • Yoshito Ikeda, Mizuki Kawakami, Yasuyuki Yamada, Masayuki Munekane, Kohei Sano, Takahiro Mukai, Taiho Kambe, Nobukazu Shitan. Chloroform Fraction of <i>Panax Ginseng</i> Extract Enhances Zip4-Mediated Zinc Influx into the Cytosol. BPB Reports. 2023. 6. 3. 108-114
  • Maho Matsumoto, Yumi Yasuoka, Yui Takakaze, Masahiro Hosoda, Shinji Tokonami, Kazuki Iwaoka, Takahiro Mukai. Evaluation of radon concentration measurements in water using the radon degassing method. Journal of Radioanalytical and Nuclear Chemistry. 2022
  • Risa Azuma, Toshihide Yamasaki, Miho C Emoto, Hideo Sato-Akaba, Kohei Sano, Masayuki Munekane, Hirotada G Fujii, Takahiro Mukai. Effect of relative configuration of TEMPO-type nitroxides on ascorbate reduction. Free radical biology & medicine. 2022. 194. 114-122
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MISC (328):
  • 池田義人, 川上瑞生, 山田泰之, 宗兼将之, 佐野紘平, 向高弘, 神戸大朋, 士反伸和. 生薬ニンジンによる亜鉛輸送体Zip4を介した亜鉛取り込みの促進. 日本生薬学会年会講演要旨集. 2023. 69th
  • Kohei Sano, Masayuki Munekane, Toshihide Yamasaki, Takahiro Mukai. Development of radioiodinated probes targeting heparanase for evaluating cancer malignancy. CANCER SCIENCE. 2022. 113. 606-606
  • Kohei Sano, Tatsuya Mizukami, Toshie Tanaka, Katsushi Takahashi, Yoshie Haratake, Masayuki Munekane, Toshihide Yamasaki, Takahiro Mukai. Internal radiotherapy of tumors using radiolabeled thermoresponsive polymers viaviavia self-aggregation under hyperthermic conditions. JOURNAL OF NUCLEAR MEDICINE. 2021. 62
  • Toshie Tanaka, Kohei Sano, Mamia Munemura, Masayori Hagimori, Rioh Moriyama, Azusa Yamamoto, Masayuki Munekane, Toshihide Yamasaki, Takahiro Mukai. Development of a radiolabeled self-assembled nanoparticle as an imaging probe for CD44-expressing tumors. NUCLEAR MEDICINE AND BIOLOGY. 2021. 96-97. S83-S84
  • 宗兼将之, 小杉亜佐実, 甘中健登, 佐野紘平, 山崎俊栄, 大河原賢一, 向高弘. 核医学診断・治療薬の母体としてのニオソームの有用性評価. 核医学(Web). 2021. 58. Supplement
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Patents (10):
Education (4):
  • 1992 - 1994 京都大学大学院 薬学研究科 修士課程製薬化学専攻
  • - 1994 Kyoto University Graduate School, Division of Pharmaceutical Sciences
  • - 1992 Kyoto University Faculty of Pharmaceutical Science
  • Kyoto University Faculty of Pharmaceutical Sciences
Work history (10):
  • 2011/04 - 現在 Kobe Pharmaceutical University
  • 2007/04 - 2011/03 Kyushu University Faculty of Pharmaceutical Sciences
  • 2004/02 - 2007/03 Kyushu University Faculty of Pharmaceutical Sciences
  • 1999/07 - 2004/01 Kyoto University Hospital
  • 1999 - 2004 Assistant Professor, Graduate School of Medicine, Kyoto University.
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Committee career (11):
  • 2019/04 - 現在 薬学教育協議会 放射薬学教科担当教員会議 委員長
  • 2017/06 - 現在 日本分子イメージング学会 編集委員
  • 2016/04 - 現在 薬学教育協議会 放射薬学教科担当教員会議 薬剤師国家試験問題WG委員
  • 2015/05 - 現在 金属の関与する生体関連反応シンポジウム(SRM) 評議員
  • 2013/02 - 現在 日本薬学会 代議員
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Awards (9):
  • 2016/07 - 日本微量元素学会 第27回日本微量元素学会学術集会 優秀演題賞受賞 細胞内遊離亜鉛イオンの検出を目的とした蛍光プローブの開発
  • 2007 - Society of Nuclear Medicine The Journal of Nuclear Medicine Editor's Choice Award 2007
  • 2004 - Society of Nuclear Medicine 2004 FIRST PLACE AWARD, OUTSTANDING BASIC SCIENCE INVESTIGATIONS
  • 2003/10 - 日本核医学会 第41回日本核医学会賞 Development of a Rhenium-186-labeled Bifunctional Radiopharmaceutical for Palliation of Painful Bone Metastases: 186Re-MAG3-HBP
  • 2003 - Young Investigator Award, Japanese Society of Nuclear Medicine
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Association Membership(s) (13):
THE JAPANESE ASSOCIATION FOR MOLECULAR TARGET THERAPY OF CANCER ,  THE ACADEMY OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY, JAPAN ,  THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM ,  JAPAN RADIOISOTOPE ASSOCIATION ,  Society of Radiopharmaceutical Sciences ,  THE JAPANESE CANCER ASSOCIATION ,  Japanese Society for Molecular Imaging ,  Society of Nuclear Medicine and Molecular Imaging ,  JAPANESE SOCIETY OF NUCLEAR MEDICINE ,  THE JAPANESE SOCIETY FOR THE STUDY OF XENOBIOTICS ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  The Society of Radiopharmaceutical Chemistry and Biology ,  The Society of Nuclear Medicine
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