Rchr
J-GLOBAL ID:200901013735393106   Update date: Nov. 15, 2024

Mukai Takahiro

ムカイ タカヒロ | Mukai Takahiro
Affiliation and department:
Job title: Associate Professor
Research field  (3): Radiology ,  Pharmacology ,  Pharmaceuticals - analytical and physicochemistry
Research keywords  (9): DDS ,  Multimodality ,  Theranostics ,  内用放射線治療薬剤 ,  分子イメージング ,  放射性薬剤 ,  Pharmacokinetics ,  Radiopharmaceutical Chemistry ,  Nuclear Medicine
Research theme for competitive and other funds  (43):
  • 2022 - 2026 外部刺激に応答するがん標的セラノスティックナノデバイスの開発
  • 2019 - 2022 Development of radiolabeled probes enabling to detect reactive oxygen species separately in living body
  • 2018 - 2020 核医学・蛍光デュアルイメージングを可能とするトリファンクショナルキレートの開発
  • 2016 - 2019 がんのラジオセラノスティックスを達成するための自己組織化ナノデバイスの開発
  • 2015 - 2017 ヘパラナーゼを分子標的とする放射性ヨウ素標識薬剤の開発
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Papers (238):
  • Yumi Yasuoka, June Takemoto, Yasutaka Omori, Nanaho Kawamoto, Nao Goda, Hiroyuki Nagahama, Jun Muto, Shinji Tokonami, Masahiro Hosoda, Takeshi Iimoto, et al. Practical cut-off value for radon concentration in indoor air using an activated-charcoal radon collector. Radiation Protection Dosimetry. 2024. 200. 16-18. 1701-1705
  • Masayuki Munekane, Miki Ozaki, Yuri Mitani, Natsuki Sakaida, Kohei Sano, Toshihide Yamasaki, Takahiro Mukai, Kenji Mishiro, Takeshi Fuchigami, Kazuma Ogawa. Development of Radiolabeled Probes with Improved Imaging Contrast by Releasing Urinary Excretable Radiolabeled Compounds from Thermosensitive Liposomes in the Blood. Molecular pharmaceutics. 2024. 21. 11. 5728-5735
  • Toshie Tanaka, Kohei Sano, Rin Kawakami, Shiho Tanaka, Masayuki Munekane, Toshihide Yamasaki, Takahiro Mukai. Electrostatically self-assembled gold nanorods with sulfated hyaluronic acid for targeted photothermal therapy for CD44-positive tumors. Nanomedicine : nanotechnology, biology, and medicine. 2024. 102781-102781
  • Fumiko Hara, Naoko Mizuyama, Takeshi Fujino, Ashok Kumar Shrestha, Thenuwara Arachchige Omila Kasun Meetiyagoda, Shinya Takada, Hideo Saji, Takahiro Mukai, Masayori Hagimori. Development of a water-soluble fluorescent Al3+ probe based on phenylsulfonyl-2-pyrone in biological systems. Analytica Chimica Acta. 2024. 1299. 342436-342436
  • Masayuki Munekane, Hinako Mori, Nao Takada, Kohei Sano, Toshihide Yamasaki, Toru Tanaka, Naoto Sasaki, Yoshiyuki Rikitake, Takahiro Mukai. Preparation and evaluation of 111In-labeled liposomes containing phosphatidylglycerol for detection of macrophages in atherosclerotic plaques. Nuclear medicine and biology. 2023. 126-127. 108388-108388
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MISC (343):
  • 尾嵜光希, 宗兼将之, 宗兼将之, 三谷柚里, 酒井田なつき, 佐野絋平, 山崎俊栄, 向高弘, 三代憲司, 淵上剛志, et al. Development of nuclear imaging agent for high-contrast cancer diagnosis with thermo-sensitive liposome. 日本薬学会年会要旨集(Web). 2024. 144th
  • 坂根輝美, 東里沙, 山崎俊栄, 佐野紘平, 向高弘. Development of a radiolabeled probe to evaluate the in vivo behavior of hypochlorous acid non-invasively. 日本薬学会年会要旨集(Web). 2024. 144th
  • 長濱果林, 山崎俊栄, 佐野紘平, 向高弘. Para-Substituent Effects on Reactivity Toward Ascorbate of 4-Oxo-TEMPO Derivatives Containing Phenyl Group at the C-2 Substituent. 日本薬学会年会要旨集(Web). 2024. 144th
  • 深田智也, 佐野紘平, 宗兼将之, 山崎俊栄, 田中将史, 向高弘. Evaluation of the effect of lipid charge on tumor accumulation of lipid-styrene maleic acid copolymer nanodiscs. 日本薬学会年会要旨集(Web). 2024. 144th
  • 佐野紘平, 田中志歩, 小平美優, 佐々木直人, 田中亨, 灘中里美, 山崎俊栄, 力武良行, 北川裕之, 萩森政頼, et al. Development of heparanase-targeted radiopharmaceuticals to detect vulnerable plaques in atherosclerosis. 日本薬学会年会要旨集(Web). 2024. 144th
more...
Patents (10):
Education (4):
  • 1992 - 1994 京都大学大学院 薬学研究科 修士課程製薬化学専攻
  • - 1994 Kyoto University Graduate School, Division of Pharmaceutical Sciences
  • - 1992 Kyoto University Faculty of Pharmaceutical Science
  • Kyoto University Faculty of Pharmaceutical Sciences
Work history (10):
  • 2011/04 - 現在 Kobe Pharmaceutical University
  • 2007/04 - 2011/03 Kyushu University Faculty of Pharmaceutical Sciences
  • 2004/02 - 2007/03 Kyushu University Faculty of Pharmaceutical Sciences
  • 1999/07 - 2004/01 Kyoto University Hospital
  • 1999 - 2004 Assistant Professor, Graduate School of Medicine, Kyoto University.
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Committee career (11):
  • 2019/04 - 現在 薬学教育協議会 放射薬学教科担当教員会議 委員長
  • 2017/06 - 現在 日本分子イメージング学会 編集委員
  • 2016/04 - 現在 薬学教育協議会 放射薬学教科担当教員会議 薬剤師国家試験問題WG委員
  • 2015/05 - 現在 金属の関与する生体関連反応シンポジウム(SRM) 評議員
  • 2013/02 - 現在 日本薬学会 代議員
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Awards (9):
  • 2016/07 - 日本微量元素学会 第27回日本微量元素学会学術集会 優秀演題賞受賞 細胞内遊離亜鉛イオンの検出を目的とした蛍光プローブの開発
  • 2007 - Society of Nuclear Medicine The Journal of Nuclear Medicine Editor's Choice Award 2007
  • 2004 - Society of Nuclear Medicine 2004 FIRST PLACE AWARD, OUTSTANDING BASIC SCIENCE INVESTIGATIONS
  • 2003/10 - 日本核医学会 第41回日本核医学会賞 Development of a Rhenium-186-labeled Bifunctional Radiopharmaceutical for Palliation of Painful Bone Metastases: 186Re-MAG3-HBP
  • 2003 - Young Investigator Award, Japanese Society of Nuclear Medicine
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Association Membership(s) (13):
THE JAPANESE ASSOCIATION FOR MOLECULAR TARGET THERAPY OF CANCER ,  THE ACADEMY OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY, JAPAN ,  THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM ,  JAPAN RADIOISOTOPE ASSOCIATION ,  Society of Radiopharmaceutical Sciences ,  THE JAPANESE CANCER ASSOCIATION ,  Japanese Society for Molecular Imaging ,  Society of Nuclear Medicine and Molecular Imaging ,  JAPANESE SOCIETY OF NUCLEAR MEDICINE ,  THE JAPANESE SOCIETY FOR THE STUDY OF XENOBIOTICS ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  The Society of Radiopharmaceutical Chemistry and Biology ,  The Society of Nuclear Medicine
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