Rchr
J-GLOBAL ID:200901014212244880   Update date: Sep. 25, 2024

Yoshioka Mitsuhiro

ヨシオカ ミツヒロ | Yoshioka Mitsuhiro
Affiliation and department:
Homepage URL  (1): https://hokudai-neuropharmacol.net/
Research field  (3): Pharmacology ,  Psychiatry ,  Neuroscience - general
Research keywords  (13): serotonin ,  stress ,  GABA ,  dopamine ,  synapse ,  クロストーク ,  monoamines ,  raphe nuclei ,  発達 ,  Hippocampus ,  medial prefrontal cortex ,  行動神経科学・神経科学 ,  神経薬理学.神経化学
Research theme for competitive and other funds  (33):
  • 2021 - 2024 Testing the hypothesis that impaired hippocampal function and increased depressive-like behavior are due to reduced serotonin synthesis in the median raphe nucleus
  • 2016 - 2019 Elucidation of neural mechanisms underlying fear memory using DREADD
  • 2012 - 2015 SSRI exerts anxiolytic effect via amygdalar 5-HTergic neural system
  • 2011 - 2012 Functional develpment of 5-HT/GABA neurons in the raphe nuclei - postnatal stress and epigenetics
  • 2009 - 2011 不安と衝動性の脳内神経機構の研究
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Papers (254):
  • Hiroyuki Kawai, Youcef Bouchekioua, Naoya Nishitani, Kazuhei Niitani, Shoma Izumi, Hinako Morishita, Chihiro Andoh, Yuma Nagai, Masashi Koda, Masako Hagiwara, et al. Median raphe serotonergic neurons projecting to the interpeduncular nucleus control preference and aversion. Nature Communications. 2022. 13. 1
  • Hitomi Sasamori, Toshiaki Asakura, Chiaki Sugiura, Youcef Bouchekioua, Naoya Nishitani, Masaaki Sato, Takayuki Yoshida, Miwako Yamasaki, Akira Terao, Masahiko Watanabe, et al. Behavioral characteristics of dopamine D5 receptor knockout mice. Scientific Reports. 2022. 12. 1
  • Youcef Bouchekioua, Mao Nebuka, Hitomi Sasamori, Naoya Nishitani, Chiaki Sugiura, Masaaki Sato, Mitsuhiro Yoshioka, Yu Ohmura. Serotonin 5-HT2C receptor knockout in mice attenuates fear responses in contextual or cued but not compound context-cue fear conditioning. Translational psychiatry. 2022. 12. 1. 58-58
  • Naoya Nishitani, Yu Ohmura, Keita Kobayashi, Taichi Murashita, Takayuki Yoshida, Mitsuhiro Yoshioka. Serotonin neurons in the median raphe nucleus bidirectionally regulate somatic signs of nicotine withdrawal in mice. Biochemical and biophysical research communications. 2021. 562. 62-68
  • Yu Ohmura, Kentaro Iwami, Srikanta Chowdhury, Hitomi Sasamori, Chiaki Sugiura, Youcef Bouchekioua, Naoya Nishitani, Akihiro Yamanaka, Mitsuhiro Yoshioka. Disruption of model-based decision making by silencing of serotonin neurons in the dorsal raphe nucleus. Current biology : CB. 2021. 31. 11. 2446-2454
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MISC (431):
Patents (2):
Books (19):
  • 専門医のための臨床精神神経薬理学テキスト
    星和書店 2021 ISBN:9784791110742
  • 薬理学
    医学書院 2018 ISBN:9784260031844
  • 系統看護学講座 専門基礎分野-疾病のなりたちと回復の促進3 薬理学
    医学書院 2017 ISBN:4260018140
  • イラストレイテッド薬理学
    丸善出版 2016 ISBN:9784621301043
  • 臨床薬理学 : ハーバード大学講義テキスト
    丸善出版 2015 ISBN:9784621089163
more...
Education (1):
  • 1978 - 1984 Hokkaido University School of Medicine
Professional career (1):
  • 博士(医学) (北海道大学)
Work history (6):
  • 1998/04 - 現在 北海道大学医学研究科 教授
  • 2017/04 - 2021/03 Hokkaido University
  • 1997/09 - 1998/03 同教授
  • 1991/06 - 1997/08 同助教授
  • 1989/07 - 1991/06 同講師
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Committee career (2):
  • 2017/10 - 2023/09 日本学術会議 第二部会員
  • 2018/04 - 2020/03 公益社団法人 日本薬理学会 理事長
Awards (2):
  • 2017/09 - 一般社団法人 北海道医師会 北海道医師会賞 セロトニンおよびセロトニン受容体の機能的役割に関する研究
  • 1995/03 - 日本薬理学会 学術奨励賞
Association Membership(s) (9):
高血圧関連疾患モデル学会 ,  国際セロトニンクラブ ,  THE JAPANESE SOCIETY OF CLINICAL PHARMACOLOGY AND THERAPEUTICS ,  THE JAPAN NEUROSCIENCE SOCIETY ,  THE JAPANESE SOCIETY FOR NEUROCHEMISTRY ,  THE JAPANESE SOCIETY OF NEUROPSYCHOPHARMACOLOGY ,  THE JAPANESE PHARMACOLOGICAL SOCIETY ,  米国薬理学会 ,  American Society for Pharmacology and Experimental Therapeutics
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