Hidetoshi Saitoh

サイトウヒデトシ | Hidetoshi Saitoh

Affiliation and department：
Job title： Assistant Professor
Homepage URL (1)： https://fukuoka.iuhw.ac.jp/faculty/ps/

Research field (1)： Neuropathology

Research keywords (3)： ATP受容体 , 疼痛 , グリア

Research theme for competitive and other funds (10)：

2020 - 2025 Modification of somatosensory behaviors by intervention of glial cell subsets
2015 - 2019 Study for the mechanism underlying neuropathic pain focusing on a subpopulation of microglia
2013 - 2018 Synaptic regulation by intracerebral microglia and chronic pain
2013 - 2016 Assessment of spinal cord chemokine signaling in the mechanism of neuropathic pain.
2011 - 2016 The role of glial cells in neuropathic pain

Show all

Papers (93)：

Kazuki Fujimori, Misuzu Sekine, Moeka Watanabe, Ryoichi Tashima, Hidetoshi Tozaki-Saitoh, Makoto Tsuda. Chemogenetic silencing of spinal cord-projecting cortical neurons attenuates Aβ fiber-derived neuropathic allodynia in mice. Neuroscience research. 2022
Tomohiro Yamashita, Sawako Kamikaseda, Aya Tanaka, Hidetoshi Tozaki-Saitoh, Jose M. M. Caaveiro, Kazuhide Inoue, Makoto Tsuda. New Inhibitory Effects of Cilnidipine on Microglial P2X7 Receptors and IL-1β Release: An Involvement in its Alleviating Effect on Neuropathic Pain. Cells. 2021. 10. 2. 434-434
Ryoichi Tashima, Keisuke Koga, Yu Yoshikawa, Misuzu Sekine, Moeka Watanabe, Hidetoshi Tozaki-Saitoh, Hidemasa Furue, Toshiharu Yasaka, Makoto Tsuda. A subset of spinal dorsal horn interneurons crucial for gating touch-evoked pain-like behavior. Proceedings of the National Academy of Sciences. 2021. 118. 3. e2021220118-e2021220118
Keisuke Koga, Yuto Shiraishi, Ryo Yamagata, Hidetoshi Tozaki-Saitoh, Miho Shiratori-Hayashi, Makoto Tsuda. Intrinsic braking role of descending locus coeruleus noradrenergic neurons in acute and chronic itch in mice. Molecular Brain. 2020. 13. 1. 144-144
Yuta Kohro, Tsuyoshi Matsuda, Kohei Yoshihara, Keita Kohno, Keisuke Koga, Ryuichi Katsuragi, Takaaki Oka, Ryoichi Tashima, Sho Muneta, Takuya Yamane, et al. Spinal astrocytes in superficial laminae gate brainstem descending control of mechanosensory hypersensitivity. Nature Neuroscience. 2020. 23. 11. 1376-1387

ｍore...

MISC (53)：

下田翔, 西村明幸, 西山和宏, 加藤百合, 田中智弘, 齊藤秀俊, 津田誠, 西田基宏. プリン作動性P2Y6受容体数の変調は圧負荷誘導性心不全を増悪させる. 臨床薬理. 2020. 51. Suppl. S257-S257
古賀啓祐, 兼久賢章, 高露雄太, 齋藤秀俊, 井上和秀, 古江秀昌, 津田誠. 脊髄後角抑制性介在神経の急性的な抑制はモルヒネ抵抗性の自発的疼痛関連行動を引き起こす. Pain Research. 2017. 32. 2. 120-120
津田誠, 齊藤秀俊, 山下智大, 松田烈士. ミクログリア脳科学辞典. 2016
Takahiro Masuda, Shosuke Iwamoto, Ryohei Yoshinaga, Hidetoshi Tozaki-Saitoh, Akira Nishiyama, Tak W. Mak, Tadatsugu Taniguchi, Tomohiko Tamura, Makoto Tsuda, Kazuhide Inoue. IRF5 directly regulates P2X4R(+) reactive state of microglia driving neuropathic pain. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 124P-124P
Yoshinori Hayashi, Saoru Koyanagi, Naoki Kusunose, Ryo Okada, Zhou Wu, Hidetoshi Saitoh, Shinichi Kohsaka, Kazuhide Inoue, Shigehiro Ohodo, Hiroshi Nakanishi. Regulation of synaptic strength are controlled by circadian rhythm of cathepsin S expression in the microglia. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 125P-125P

ｍore...

Lectures and oral presentations (86)：

動物モデルを用いた心理社会的ストレスと痛みの科学的理解へのアプローチ
(第62 回日本心身医学会総会ならびに学術講演会 2021)
心理社会的ストレスが慢性疼痛病態モデルに及ぼす影響
(第29回神経行動薬理若手研究者の集い 2020)
Involvement of EPAC and TPL2 in IL-1β production in microglial cells following activation of β-adrenergic receptors
(第93回日本薬理学会年会 2020)
Microglial contribution to reserpine-induced mechanical hypersensitivity
(自然科学研究機構生理学研究所2019年度国際学術集会:防御的生存回路研究の最先端 2020)
Microglial role in the pathological pain
(8th Asian pain symposium 2019)

ｍore...

Education (1)：

- 2006 Kyushu University

Professional career (1)：

薬学 (九州大学)

Work history (3)：

2021/04 - 現在 International University of Health and Welfare
2015/01 - 2021/03 Kyushu University School of Pharmaceutical Sciences
2008 - 2014/12 九州大学薬学研究科(研究院) 助教

Association Membership(s) (5)：

THE JAPAN NEUROSCIENCE SOCIETY , THE JAPANESE SOCIETY FOR NEUROCHEMISTRY , JAPANESE ASSOCIATION FOR THE STUDY OF PAIN , THE PHARMACEUTICAL SOCIETY OF JAPAN , THE JAPANESE PHARMACOLOGICAL SOCIETY

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page