Tomita Kengo

トミタケンゴ | Tomita Kengo

Affiliation and department：

Research keywords (4)：メタボリックシンドローム関連疾患 , 糖代謝 , 臓器線維症 , 臓器相関

Research theme for competitive and other funds (10)：

2021 - 2025 過栄養・肥満による臓器線維化の不顕性進展機構の解明と、疾患治療への応用
2018 - 2021 Elucidation of the pathological mechanism of obesity-related liver cancer and development of the new treatment methods, focusing on secretory factors from hepatic stellate cells
2015 - 2018 Establishment of novel therapies for steatohepatitis and liver cancer, by targeting the free cholesterol-mediated signaling pathway.
2011 - 2013 Unraveling the role of Angptl2 in the pathogenesis of steatohepatitis and liver cancer
2008 - 2010 Analysis of the paradoxical correlation between hepatic insulin resistance and oxidative stress in the pathogenesis of steatohepatitis

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Papers (94)：

Rina Tanemoto, Masaaki Higashiyama, Akira Tomioka, Suguru Ito, Akinori Mizoguchi, Shin Nishii, Kenichi Inaba, Akinori Wada, Nao Sugihara, Yoshinori Hanawa, et al. Chronic skin damage induces small intestinal damage via IL-13-induced apoptosis. Clinical and experimental immunology. 2024. 217. 3. 240-252
Kazuki Horiuchi, Masaaki Higashiyama, Hiroyuki Tahara, Yuta Yoshidome, Kana Ayaki, Hiroyuki Nishimura, Akira Tomioka, Kazuyuki Narimatsu, Shunsuke Komoto, Kengo Tomita, et al. Absence of Paneth Cell Metaplasia to Predict Clinical Relapse in Ulcerative Colitis with Endoscopically Quiescent Mucosa. Digestive diseases and sciences. 2024
Suguru Ito, Masaaki Higashiyama, Hiroyuki Nishimura, Akira Tomioka, Rina Tanemoto, Shin Nishii, Akinori Mizoguchi, Yoshihiro Akita, Yoshikiyo Okada, Chie Kurihara, et al. The Role of Gut Microbiota and Innate Immune Response in an Autoimmune Pancreatitis Model. Pancreas. 2024. 53. 7. e617-e626
Asuka Uto, Yuki Ishinoda, Takamasa Asaga, Yuki Tanahashi, Ai Kobayashi, Hitomi Meshino, Maki Okazaki, Kengo Tomita, Akira Kasuga, Naoki Oshima. Imeglimin for Type 2 Diabetes Mellitus: Its Efficacy and Insight Into the Potential Benefit for Renal and Liver Function. Cureus. 2024. 16. 8. e66322
Nao Sugihara, Yoshikiyo Okada, Akira Tomioka, Suguru Ito, Rina Tanemoto, Shin Nishii, Akinori Mizoguchi, Kenichi Inaba, Yoshinori Hanawa, Kazuki Horiuchi, et al. Probiotic Yeast from Miso Ameliorates Stress-Induced Visceral Hypersensitivity by Modulating the Gut Microbiota in a Rat Model of Irritable Bowel Syndrome. Gut and liver. 2024. 18. 3. 465-475

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MISC (40)：

Chie Kurihara, Toshihide Ohmori, Kenichi Inaba, Nao Sugihara, Yoshinori Hanawa, Kazuki Horiuchi, Akinori Wada, Shin Nishii, Akinori Mizoguchi, Suguru Ito, et al. THERAPEUTIC EFFICACY OF GRANULOCYTE AND MONOCYTE ADSORPTIVE APHERESIS IS CORRELATED WITH COLONIC MUCOSAL EXPRESSION OF TIGHT JUNCTION MOLECULES IN ULCERATIVE COLITIS. GASTROENTEROLOGY. 2021. 160. 6. S504-S504
Chie Kurihara, Toshihide Ohmori, Kenichi Inaba, Nao Sugihara, Yoshinori Hanawa, Kazuki Horiuchi, Akinori Wada, Shin Nishii, Akinori Mizoguchi, Suguru Ito, et al. EFFICACY OF GRANULOCYTE AND MONOCYTE ADSORPTIVE APHERESIS TREATMENT IS CORRELATED WITH COLONIC MUCOSAL EXPRESSION OF TH17-ASOCIATED CYTOKINES IN ULCERATIVE COLITIS. GASTROENTEROLOGY. 2020. 158. 6. S1046-S1046
Akinori Wada, Masaaki Higashiyama, Suguru Ito, Rina Tanemoto, Akinori Mizoguchi, Shin Nishii, Kenichi Inaba, Nao Sugihara, Yoshinori Hanawa, Kazuki Horiuchi, et al. ANTIOXIDANT EFFECT OF URIC ACID AMELIORATES NSAIDS INDUCED ENTEROPATHY AND CHANGES GUT MICROBIOTA. GASTROENTEROLOGY. 2020. 158. 6. S504-S504
Chie Kurihara, Toshihide Ohmori, Hirotaka Furuhashi, Kenichi Inaba, Nao Sugihara, Yoshinori Hanawa, Kazuki Horiuchi, Akinori Wada, Shin Nishii, Akinori Mizoguchi, et al. HIGHER TNF alpha AND MIP-1 beta EXPRESSION IN PRETREATMENT COLONIC MUCOSA HAVE POTENTIAL TO PREDICT OF ACHIEVING MUCOSAL HEALING BY GRANULOCYTE AND MONOCYTE ADSORPTIVE APHERESIS THERAPY IN ULCERATIVE COLITIS PATIENTS. GASTROENTEROLOGY. 2019. 156. 6. S1146-S1146
Akinori Wada, Masaaki Higashiyama, Akinori Mizoguchi, Shin Nishii, Kenichi Inaba, Nao Sugihara, Yoshinori Hanawa, Kazuki Horiuchi, Hirotaka Furuhashi, Naoki Shibuya, et al. HYPERURICEMIA AMELIORATES INTESTINAL INFLAMMATION ALONG WITH ALTERED GUT MICROBIOTA. GASTROENTEROLOGY. 2019. 156. 6. S707-S707

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Education (2)：

1995 - 1999 慶應義塾大学大学院医学研究科博士課程
1987 - 1993 Keio University School of Medicine

Work history (1)：

2017/04 - 現在 National Defense Medical College Department of Internal Medicine Associate Professor

Awards (20)：

2019 - 日本肝臓学会研究奨励賞
2018 - 大樹生命厚生財団研究助成賞
2018 - テルモ生命科学芸術財団研究開発助成賞
2018 - ノバルティス科学振興財団研究奨励賞
2018 - 平成30年度ギリアドサイエンシズ社研究助成賞

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