Tomita Kengo

トミタケンゴ | Tomita Kengo

Affiliation and department：
Job title：准教授

Research keywords (3)：メタボリックシンドローム関連疾患 , 臓器線維症 , 臓器相関

Research theme for competitive and other funds (10)：

2021 - 2025 過栄養・肥満による臓器線維化の不顕性進展機構の解明と、疾患治療への応用
2018 - 2021 Elucidation of the pathological mechanism of obesity-related liver cancer and development of the new treatment methods, focusing on secretory factors from hepatic stellate cells
2015 - 2018 Establishment of novel therapies for steatohepatitis and liver cancer, by targeting the free cholesterol-mediated signaling pathway.
2011 - 2013 Unraveling the role of Angptl2 in the pathogenesis of steatohepatitis and liver cancer
2008 - 2010 Analysis of the paradoxical correlation between hepatic insulin resistance and oxidative stress in the pathogenesis of steatohepatitis

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Papers (84)：

Yoshihiro Akita, Masaaki Higashiyama, Chie Kurihara, Suguru Ito, Shin Nishii, Akinori Mizoguchi, Kenichi Inaba, Rina Tanemoto, Nao Sugihara, Yoshinori Hanawa, et al. Ameliorating Role of Hydrogen-Rich Water Against NSAID-Induced Enteropathy via Reduction of ROS and Production of Short-Chain Fatty Acids. Digestive diseases and sciences. 2022. 1-11
Yoshikiyo Okada, Nao Sugihara, Shin Nishii, Suguru Itoh, Akinori Mizoguchi, Rina Tanemoto, Kazuki Horiuchi, Akira Tomioka, Hiroyuki Nishimura, Masaaki Higashiyama, et al. Transgenerational impacts of oral probiotic administration in pregnant mice on offspring gut immune cells and colitis susceptibility. Journal of gastroenterology and hepatology. 2022
Kenichi Inaba, Masaaki Higashiyama, Chikako Watanabe, Akira Tomioka, Suguru Ito, Rina Tanemoto, Akinori Mizoguchi, Shin Nishii, Akinori Wada, Nao Sugihara, et al. Basophils play a proinflammatory role in oxazolone-induced chronic intestinal inflammation. Journal of gastroenterology and hepatology. 2022
秋田義博, 東山正明, 冨岡明, 伊東傑, 西井慎, 溝口明範, 種本理那, 因幡健一, 杉原奈央, 塙芳典, et al. NSAIDs起因性小腸炎に対する水素水の有効性. 日本消化器病学会雑誌. 2021. 118. 臨増大会. A756-A756
Akinori Wada, Masaaki Higashiyama, Dai Hirata, Suguru Ito, Rina Tanemoto, Shin Nishii, Akinori Mizoguchi, Kenichi Inaba, Nao Sugihara, Yoshinori Hanawa, et al. Changes in Colonic Inflammation Related with Takayasu Arteritis during a 10-year Observation Period. Internal medicine (Tokyo, Japan). 2021

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MISC (39)：

Chie Kurihara, Toshihide Ohmori, Kenichi Inaba, Nao Sugihara, Yoshinori Hanawa, Kazuki Horiuchi, Akinori Wada, Shin Nishii, Akinori Mizoguchi, Suguru Ito, et al. THERAPEUTIC EFFICACY OF GRANULOCYTE AND MONOCYTE ADSORPTIVE APHERESIS IS CORRELATED WITH COLONIC MUCOSAL EXPRESSION OF TIGHT JUNCTION MOLECULES IN ULCERATIVE COLITIS. GASTROENTEROLOGY. 2021. 160. 6. S504-S504
Chie Kurihara, Toshihide Ohmori, Kenichi Inaba, Nao Sugihara, Yoshinori Hanawa, Kazuki Horiuchi, Akinori Wada, Shin Nishii, Akinori Mizoguchi, Suguru Ito, et al. EFFICACY OF GRANULOCYTE AND MONOCYTE ADSORPTIVE APHERESIS TREATMENT IS CORRELATED WITH COLONIC MUCOSAL EXPRESSION OF TH17-ASOCIATED CYTOKINES IN ULCERATIVE COLITIS. GASTROENTEROLOGY. 2020. 158. 6. S1046-S1046
Akinori Wada, Masaaki Higashiyama, Suguru Ito, Rina Tanemoto, Akinori Mizoguchi, Shin Nishii, Kenichi Inaba, Nao Sugihara, Yoshinori Hanawa, Kazuki Horiuchi, et al. ANTIOXIDANT EFFECT OF URIC ACID AMELIORATES NSAIDS INDUCED ENTEROPATHY AND CHANGES GUT MICROBIOTA. GASTROENTEROLOGY. 2020. 158. 6. S504-S504
Chie Kurihara, Toshihide Ohmori, Hirotaka Furuhashi, Kenichi Inaba, Nao Sugihara, Yoshinori Hanawa, Kazuki Horiuchi, Akinori Wada, Shin Nishii, Akinori Mizoguchi, et al. HIGHER TNF alpha AND MIP-1 beta EXPRESSION IN PRETREATMENT COLONIC MUCOSA HAVE POTENTIAL TO PREDICT OF ACHIEVING MUCOSAL HEALING BY GRANULOCYTE AND MONOCYTE ADSORPTIVE APHERESIS THERAPY IN ULCERATIVE COLITIS PATIENTS. GASTROENTEROLOGY. 2019. 156. 6. S1146-S1146
Akinori Wada, Masaaki Higashiyama, Akinori Mizoguchi, Shin Nishii, Kenichi Inaba, Nao Sugihara, Yoshinori Hanawa, Kazuki Horiuchi, Hirotaka Furuhashi, Naoki Shibuya, et al. HYPERURICEMIA AMELIORATES INTESTINAL INFLAMMATION ALONG WITH ALTERED GUT MICROBIOTA. GASTROENTEROLOGY. 2019. 156. 6. S707-S707

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Education (2)：

1995 - 1999 慶應義塾大学大学院医学研究科博士課程
1987 - 1993 Keio University School of Medicine

Work history (1)：

2017/04 - 現在 National Defense Medical College Division of Gastroenterology and Hepatology, Department of Internal Medicine Associate Professor

Awards (20)：

2019 - 日本肝臓学会研究奨励賞
2018 - 大樹生命厚生財団研究助成賞
2018 - テルモ生命科学芸術財団研究開発助成賞
2018 - ノバルティス科学振興財団研究奨励賞
2018 - 平成30年度ギリアドサイエンシズ社研究助成賞

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