Research theme for competitive and other funds (21)：
2023 - 2027 エクソソームと細胞集合体の融合による次世代型歯髄再生療法の確立
2022 - 2025 Development of a novel peptide drug against irreversible pulpitis using rat caries derived pulpitis model
2021 - 2024 口腔細菌の薬剤耐性化および各種抗生剤に対する交叉耐性獲得の網羅的検索
2017 - 2020 Development of pulp capping material based on the wound healing mechanism of the pulp tissue using bioinformatics
2014 - 2017 Development of hydrogels with the ability to release antimicrobials for long term and their application to various resin-based materials
2017 - S-PRGフィラー含有水性ペーストの覆髄剤および根管貼薬剤としての応用
2016 - S-PRG含有試作セメントならびに新規イオン追加試作セメントの覆髄剤としての応用
2012 - 2015 Comprehensive in situ analysis of dental biofilm formation and control
2013 - Identification of degraded dentin matrix proteins and application as a pulp capping material
2011 - 象牙質基質タンパク分解産物が象牙質-歯髄複合体の治癒に与える影響
2007 - 2010 The pursuit of conservative dental treatment design in a new era by diverse utilization of an antibacterial monomer
2009 - 修復象牙質形成過程におけるマトリックスメタロプロテアーゼの局在および機能解析
2008 - 修復象牙質形成における発現遺伝子のプロファイリング
2006 - 2007 新規の化学的歯質接着メカニズムの創出-プレ配置された水素結合の応用-
2007 - 修復象牙質形成における発現遺伝子のプロファイリング
2006 - IL-6シグナルに潜むネガティブフィードバック機構の炎症性骨・歯根吸収への応用
2006 - う蝕原性細菌表層におけるレジンモノマーの重合現象に関する多面的解析
2005 - う蝕原性細菌表層におけるレジンモノマーの重合現象に関する多面的解析
Pulp Biology
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歯髄生物学
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Papers (58)：
Aonan Li, Jun-Ichi Sasaki, Hailing Huang, Gabriela L. Abe, Toshihiro Inubushi, Yusuke Takahashi, Mikako Hayashi, Satoshi Imazato. Effect of Heparan Sulfate on Vasculogenesis and Dentinogenesis of Dental Pulp Stem Cells. Journal of Endodontics. 2024. 50. 8. 1108-1116
Hazuki Maezono, Kittipit Klanliang, Tsuyoshi Shimaoka, Yoko Asahi, Yusuke Takahashi, Zhejun Wang, Ya Shen, Markus Haapasalo, Mikako Hayashi. Effects of Sodium Hypochlorite Concentration and Application Time on Bacteria in an Ex Vivo Polymicrobial Biofilm Model. Journal of endodontics. 2024. 50. 6. 814-819
Bruno Cavalcanti, Waruna Lakmal Dissanayaka, Yusuke Takahashi. Editorial: Molecular pathways and novel therapeutic targets in regenerative dentistry. Frontiers in Dental Medicine. 2024. 5
Ryousuke Tanaka, Satoshi Yamaguchi, Yusuke Takahashi, Satoshi Imazato, Mikako Hayashi. Mechanical behavior of endodontically treated teeth: A three-dimensional finite element analysis using displacement vector. Journal of Prosthodontics. 2024
Toshihiro Inubushi, Nag Priyanka, Masakatsu Watanabe, Yusuke Takahashi, Shinnosuke Kusano, Hiroshi Kurosaka, Silvana Papagerakis, Petros Papagerakis, Mikako Hayashi, Takashi Yamashiro. On-demand chlorine dioxide solution enhances odontoblast differentiation through desulfation of cell surface heparan sulfate proteoglycan and subsequent activation of canonical Wnt signaling. Frontiers in Cell and Developmental Biology. 2023. 11. 1271455-1271455
森山輝一, 岡本基岐, 松本紗也子, 渡邉昌克, 中谷公貴, 岩崎幸司, 齋多遼太郎, 西村有起, 高橋雄介, 林美加子. A Case Report: Successful Root Canal Treatment Using Resin Sealer Without Gutta-percha Point. 日本歯科保存学会学術大会プログラムおよび講演抄録集(Web). 2023. 158th
松本紗也子, 岡本基岐, HUANG Hailing, 森山輝一, 中谷公貴, 渡邉昌克, 高橋雄介, 林美加子. Evaluation of Calcium Silicate Cements Containing Resin Components Using a Rat Caries-Derived Reversible Pulpitis Model. 日本歯科保存学会学術大会プログラムおよび講演抄録集(Web). 2023. 159th
森山輝一, 岡本基岐, 松本紗也子, 渡邉昌克, HUANG Hailing, 高橋雄介, 林美加子. Evaluation of the localization of leptin in a rat caries derived pulpitis model. 日本歯科保存学会学術大会プログラムおよび講演抄録集(Web). 2022. 156th
森山輝一, 岡本基岐, 松本紗也子, 渡邉昌克, HUANG Hailing, 中谷公貴, 高橋雄介, 林美加子. Establishment of novel diagnostic methods for reversible and irreversible pulpitis associated with caries progression using ultra-high magnetic field MRI. 日本歯科保存学会学術大会プログラムおよび講演抄録集(Web). 2022. 157th
渡邉昌克, 岡本基岐, 小道俊吾, HAILING Huang, 松本紗也子, 森山輝一, 高橋雄介, 林美加子. Search for the functional site of a protein that promotes pulpal wound healing process. 日本歯科保存学会学術大会プログラムおよび講演抄録集(Web). 2022. 156th
- 2002 Osaka University Graduate School, Division of Dental Research
- 1998 Osaka University Faculty of Dentistry
Professional career (1)：
PhD (Osaka University)
Work history (7)：
2015/04/01 - 現在 Osaka University Osaka University Dental Hospital Restorative Dentistry and Endodontology Associate Professor
2010/05 - 2015/03 Osaka University Graduate School of Dentistry Department of Restorative Dentistry and Endodontology, Assistant Professor
2009/05 - 2010/04 The University of Birmingham School of Dentistry, Department of Oral Biology, Honorary Visiting Research Fellow
2007/04 - 2009/03 Assistant Professor
2006/01/01 - 2007/03/31 Osaka University Graduate School of Dentistry Course for Molecular Oral Biology and Dentistry Research Assistant
2005/04/01 - 2005/12/31 Osaka University Graduate School of Dentistry Course for Molecular Oral Biology and Dentistry Specially Appointed Researcher
2002/04 - 2005/03 大阪大学歯学部附属病院・医員
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Awards (7)：
2020/10 - Osaka University Graduate School of Dentisry Dean Award of Osaka University Graduate School of Dentistry
2020/06 - The Osaka University Dental Society Osaka University Dental Society Excellent Research Encouragement Award Lithium-containing surface pre-reacted glass fillers enhance hDPSC functions and induce reparative dentin formation in a rat pulp capping model through activation of Wnt/b-catenin signaling
2019/03 - 大阪大学大学院歯学研究科 平成30年度大阪大学歯学研究科長賞(研究分野)
2017/09 - 日本レーザー歯学会 日本レー ザー歯学会優秀発表賞
2014/07 - 大阪大学 大阪大学総長奨励賞
2014/06 - 日本歯科保存学会 日本歯科保存学会 年間優秀論文賞
2005/06 - 日本歯科保存学会 日本歯科保存学会奨励賞
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Association Membership(s) (8)：
Japanese Association for Dental Research
, International Association for Dental Research
, Japanese Association for Dental Research
, International Association for Dental Research
, 日本歯科保存学会
, 大阪大学歯学会
, Japanese Society for Laser Dentistry
, 日本歯内療法学会
