Research theme for competitive and other funds (8)：
2022 - 2025 Analysis of differentiation mechanism of bovine trophoblast cells into placental component cells.
2019 - 2022 ウシの妊娠における着床成立時の子宮内環境の解明
2016 - 2020 Establishment and re-establishment of uterine environment for pregnancy success
2016 - 2019 Role of autophagy dysfunction in environmental electrophile-induced cognitive disorder
2015 - 2018 妊娠率向上を目指したウシ内在性レトロウイルスの機能解析
2013 - 2015 ウシ胎盤特有の形態形成に関与するレトロエレメントの解析
2011 - 2013 新規妊娠認識物質の探索:受胎率向上への展望
1999 - 2005 Luteinization
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Papers (77)：
Rulan Bai, Kazuya Kusama, Yuta Matsuno, Hanako Bai, Toshihiro Sakurai, Koji Kimura, Kazuhiko Imakawa. Expression of NFIL3 and CEBPA regulated by IFNT induced-PGE2 in bovine endometrial stromal cells during the pre-implantation period. Frontiers in endocrinology. 2023. 14. 1075030-1075030
Kazuya Kusama, Rulan Bai, Yuta Matsuno, Atsushi Ideta, Toshihiro Sakurai, Kentaro Nagaoka, Masatoshi Hori, Kazuhiko Imakawa. Characterization of Serum Metabolome and Proteome Profiles Identifies SNX5 Specific for Pregnancy Failure in Holstein Heifers. Life. 2022. 12. 2. 309-309
Ryoya Takizawa, Sahoko Ichihara, Cai Zong, Kazuo Kinoshita, Toshihiro Sakurai, Akihiko Ikegami, Nathan Mise, Gaku Ichihara. 1,2-Dichloropropane induces γ-H2AX expression in human cholangiocytes only in the presence of macrophages. Toxicology letters. 2021. 349. 134-144
Hirona Murata, Hiroki Kunii, Kazuya Kusama, Toshihiro Sakurai, Hanako Bai, Manabu Kawahara, Masashi Takahashi. Heat stress induces oxidative stress and activates the KEAP1-NFE2L2-ARE pathway in bovine endometrial epithelial cells. Biology of Reproduction. 2021
Frederick Adams Ekuban, Cai Zong, Madoka Takikawa, Kota Morikawa, Toshihiro Sakurai, Sahoko Ichihara, Ken Itoh, Masayuki Yamamoto, Seiichiroh Ohsako, Gaku Ichihara. Genetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice. Toxicology. 2021. 456. 152785-152785
X. Zhang, K. Morikawa, Y. Mori, C. Zong, L. Zhang, E. Garner, C. Huang, W. Wu, J. Chang, D. Nagashima, et al. Proteomic Analysis of Liver Proteins of Mice Exposed to 1,2-dichloropropane. Society of Toxicology 58th Annual Meeting (SOT2018). 2019
Establishment of in vitro assessment system for conceptus attachment to the uterine epithelial cells
(2011)
Epigenetic regulation of gene expression in the bovine trophoblast
(2011)
Education (1)：
- 2006 Tokyo University of Pharmacy and Life Science Pharmaceutical Sciences
Professional career (1)：
Ph.D. (Tokyo University of Pharmacy and Life Science)
Work history (5)：
2019/04 - 現在 Ohu University The School of Pharmaceutical Science Associate professor
2014/04 - 2019/03 Tokyo University of Science Faculty of Phamaceutical Sciences Assistant Professor
2013/04 - 2014/03 Yokohama University of Pharmacy Faculty of Phamacy Lecturer
2006/08 - 2013/03 University of Tokyo Graduate School of Agricultural and Life Sciences Research Assistant Professor
2006/04 - 2006/07 Tokai University Postdoctoral fellow
Association Membership(s) (5)：
Society for the study of reproduction
, JAPANESE SOCIETY OF ANIMAL SCIENCE
, THE JAPANESE SOCIETY FOR HYGIENE
, THE PHARMACEUTICAL SOCIETY OF JAPAN
, SOCIETY FOR REPRODUCTION AND DEVELOPMENT
