Rchr
J-GLOBAL ID:200901015764470864   Update date: Jun. 17, 2024

Yamazaki Soh

ヤマザキ ソウ | Yamazaki Soh
Affiliation and department:
Job title: Associate Professor
Research field  (3): Molecular biology ,  Functional biochemistry ,  Structural biochemistry
Research keywords  (5): JunB ,  IκBζ ,  転写調節因子 ,  分子生物学 ,  Molecular Biology
Research theme for competitive and other funds  (15):
  • 2022 - 2025 IL-17シグナリングを介した腸上皮細胞の機能調節
  • 2021 - 2022 腸上皮細胞による腸内細菌叢の調節と免疫恒常性の維持機構
  • 2019 - 2022 Regulation of T cell functions by the transcription factor JunB
  • 2017 - 2019 肝細胞死亢進マウスを用いた非アルコール性脂肪性肝炎のバイオマーカーと治療法の開発
  • 2016 - 2018 転写調節因子IκBζとその結合因子による免疫応答の制御機構
Show all
Papers (43):
  • Yuichi Tsuchiya, Takao Seki, Kenta Kobayashi, Sachiko Komazawa-Sakon, Shigeyuki Shichino, Takashi Nishina, Kyoko Fukuhara, Kenichi Ikejima, Hidenari Nagai, Yoshinori Igarashi, et al. Fibroblast growth factor 18 stimulates the proliferation of hepatic stellate cells, thereby inducing liver fibrosis. Nature communications. 2023. 14. 1. 6304-6304
  • Takashi Nishina, Yutaka Deguchi, Mika Kawauchi, Chen Xiyu, Soh Yamazaki, Tetuo Mikami, Hiroyasu Nakano. Interleukin 11 confers resistance to dextran sulfate sodium-induced colitis in mice. iScience. 2023. 26. 2. 105934-105934
  • Soh Yamazaki, Naohiro Inohara, Masaki Ohmuraya, Yousuke Tsuneoka, Hideo Yagita, Takaharu Katagiri, Takashi Nishina, Tetuo Mikami, Hiromasa Funato, Kimi Araki, et al. IκBζ controls IL-17-triggered gene expression program in intestinal epithelial cells that restricts colonization of SFB and prevents Th17-associated pathologies. Mucosal immunology. 2022. 15. 6. 1321-1337
  • Takashi Nishina, Yutaka Deguchi, Daisuke Ohshima, Wakami Takeda, Masato Ohtsuka, Shigeyuki Shichino, Satoshi Ueha, Soh Yamazaki, Mika Kawauchi, Eri Nakamura, et al. Interleukin-11-expressing fibroblasts have a unique gene signature correlated with poor prognosis of colorectal cancer. Nature communications. 2021. 12. 1. 2281-2281
  • Katagiri T, Kameda H, Nakano H, Yamazaki S. Regulation of T cell differentiation by the AP-1 transcription factor Jun B. Immunological Medicine. 2021. 44. 3. 197-203
more...
MISC (25):
Lectures and oral presentations  (37):
  • Fibroblast growth factor 18 stimulates the proliferation of hepatic stellate cells, thereby inducing liver fibrosis
    (第52回免疫学会学術集会 2024)
  • Unraveling the Role of IL-11-Producing Fibroblasts in Colon Homeostasis
    (The 46th Annual Meeting of the Molecular Biology Society of Japan 2023)
  • IκBζ controls IL-17-triggered gene expression program in intestinal epithelial cells that restricts colonization of SFB and prevents Th17-associated pathologies
    (第77回東邦医学会総会 2023)
  • 腸上皮細胞におけるIκBζの役割:IL-17応答性の遺伝子発現を介した腸内細菌叢の調節と自己免疫疾患の抑制
    (第96回日本生化学会大会 2023)
  • 細胞死不全マウスの免疫制御異常の解析
    (令和5年度 適応・修復領域 若手主体の会議 2023)
more...
Education (4):
  • - 1997 Kyushu University
  • - 1997 Kyushu University Graduate School, Division of Medical Sciences
  • - 1992 Tohoku University Faculty of Science Department of Biology
  • - 1992 Tohoku University Faculty of Science
Professional career (1):
  • (BLANK) (Kyushu University)
Work history (5):
  • 2015/04 - 現在 Toho University School of Medicine, Faculty of Medicine
  • 2006/10 - 2015/03 九州大学大学院 医学研究院 講師
  • 1999/04 - 2006/09 九州大学大学院 医学研究院 助手
  • 1997 - 1999 日本ロシュ(株) 研究員
  • 1997 - 1999 NIPPON ROCHE RESEARCH CENTER, research worker
Awards (1):
  • 2010/05 - 日本生化学会 平成22年度日本生化学会九州支部学術奨励賞 自然免疫系で重要な転写調節因子IκB-ζの発見とその作用機序の解明
Association Membership(s) (3):
日本分子生物学会 ,  日本生化学会 ,  THE JAPANESE SOCIETY FOR IMMUNOLOGY
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