TOSHINOBU FUJIWARA

フジワラトシノブ | TOSHINOBU FUJIWARA

Affiliation and department：
Homepage URL (1)： http://www.phar.kindai.ac.jp/biochemistry/

Research field (2)： Functional biochemistry , Molecular biology

Research keywords (4)： RNA engineering , Analyses of RNA binding proteins , The initiation of mammalian protein synthesis , RNA ribosome translation

Research theme for competitive and other funds (15)：

2022 - 2025 Tissue-specific regulation of translation initiation mediated by ribosome heterogeneity
2019 - 2022 A multidisciplinary approach to establish the structural basis of dosage compensation
2017 - 2019 Elucidation of the operation principle of the translation repression by microRNA machinery in human
2016 - 2019 Creation of RNA aptamers aiming at the creation of new antifungal drug
2016 - 2019 The coupling mechanism of translation and mRNA degradation regulated by RNA binding protein in response to cell signals

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Papers (55)：

Hikari Nishisaka, Takumi Tomohiro, Kako Fukuzumi, Akira Fukao, Yoshinori Funakami, Toshinobu Fujiwara. Deciphering the Akt1-HuD interaction in HuD-mediated neuronal differentiation. Biochimie. 2024. 221. 20-26
Hikari Nishisaka, Takumi Tomohiro, Akira Fukao, Yoshinori Funakami, Toshinobu Fujiwara. Neuronal RNA-Binding Protein HuD Interacts with Translation Initiation Factor eIF3. Biological & pharmaceutical bulletin. 2023. 46. 2. 158-162
Toru Suzuki, Miyuki Hoshina, Saori Nishijima, Naosuke Hoshina, Chisato Kikuguchi, Takumi Tomohiro, Akira Fukao, Toshinobu Fujiwara, Tadashi Yamamoto. Regulation of CCR4-NOT complex deadenylase activity and cellular responses by MK2-dependent phosphorylation of CNOT2. RNA biology. 2022. 19. 1. 234-246
Akira Fukao, Takumi Tomohiro, Toshinobu Fujiwara. Translation Initiation Regulated by RNA-Binding Protein in Mammals: The Modulation of Translation Initiation Complex by Trans-Acting Factors. Cells. 2021. 10. 7
Yuki Kanda, Ryosuke Satoh, Teruaki Takasaki, Naofumi Tomimoto, Kiko Tsuchiya, Chun An Tsai, Taemi Tanaka, Shu Kyomoto, Kozo Hamada, Toshinobu Fujiwara, et al. Sequestration of the PKC ortholog Pck2 in stress granules as a feedback mechanism of MAPK signaling in fission yeast. Journal of cell science. 2021. 134. 2

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MISC (115)：

森あゆみ, 宮尾真衣, 友廣拓生, 深尾亜喜良, 足達俊吾, 夏目徹, 尾野本浩司, 米山光俊, 鈴木亨, 山本雅, et al. Translation control mediated by stress granule related factors G3BP1/2. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
宮尾真衣, 森あゆみ, 坂村由梨佳, 友廣拓生, 深尾亜喜良, 船上仁範, 足達俊吾, 夏目徹, 尾野本浩司, 米山光俊, et al. Redefining miRISC-mediated translation regulation. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
西阪皓理, 友廣拓生, 深尾亜喜良, 船上仁範, 藤原俊伸. Analysis of translation regulation mechanisms by ARE-binding protein, AUF1. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
平河顕也, 友廣拓生, 深尾亜喜良, 船上仁範, 藤原俊伸. The mechanism of Translation Initiation Regulated by Neuronal-specific RNA-binding protein. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
鈴木亨, 友廣拓生, 菊口千智, 深尾亜喜良, 藤原俊伸, 山本雅. Different roles of catalytic subunits in the CCR4-NOT deadenylase complex. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th

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Professional career (1)：

Work history (7)：

2015/04 - 現在 Graduate School of Pharmaceutical Sciences, Kindai University Laboratory of Biochemistry Professor
2013/04 - 2015/03 Graduate School of Pharmaceutical Sciences, Nagoya City University Laboratory of Hygienic Chemistry Professor
2011/04 - 2013/03 Microbial Chemistry Research Foundation Institute of Microbial Chemistry Principal Investigator
2010/04 - 2011/03 Organization of Advanced Science and Technology, Kobe Univ. Core Team Associate Professor
2007/04 - 2010/03 Graduate School of Engineering, Kobe Univ. Department of Chemical Science and Engineering Associate Professor

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Committee career (1)：

Awards (5)：

Association Membership(s) (2)：

日本RNA学会 , 日本分子生物学会

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