Ishino Fumitoshi

イシノフミトシ | Ishino Fumitoshi

Affiliation and department：
Job title： adjunct lecturer
Homepage URL (1)： http://www.tmd.ac.jp/mri/epgn/

Research field (3)： Evolutionary biology , Genomics , Molecular biology

Research keywords (9)： domestication , Evolution of viviparity , placentation , 体細胞クローン動物 , 哺乳類の進化(系統発生) , レトロトランスポゾン , 哺乳類の個体発生 , ゲノムインプリンティング , エピジェネティクス

Research theme for competitive and other funds (9)：

2023 - 2026 エクソソームとして機能するPEG10によるがん転移機構の解析
2016 - 2019 ゲノムインプリンティング機構とインプリント遺伝子の機能解析
2011 - 2016 哺乳類特異的ゲノム機能の機能
2006 - 2011 ゲノム刷り込みに関係する哺乳類特異的遺伝子群の個体発生・系統発生における機能
1998 - 2004 哺乳類特異的ゲノム機能の機能

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Papers (111)：

Fumitoshi Ishino, Johbu Itoh, Ayumi Matsuzawa, Masahito Irie, Toru Suzuki, Yuichi Hiraoka, Masanobu Yoshikawa, Tomoko Kaneko-Ishino. RTL4, a Retrovirus-Derived Gene Implicated in Autism Spectrum Disorder, Is a Microglial Gene That Responds to Noradrenaline in the Postnatal Brain. International Journal of Molecular Sciences. 2024. 25. 24. 13738-13738
Yoshifumi Fujioka, Hirosuke Shiura, Masayuki Ishii, Ryuichi Ono, Tsutomu Endo, Hiroshi Kiyonari, Yoshikazu Hirate, Hikaru Ito, Masami Kanai-Azuma, Takashi Kohda, et al. Targeting of retrovirus-derivedRtl8a/8breduces social response and increases apathy-like behavior associated with GABRB2 reduction. 2024
Fumitoshi Ishino, Johbu Itoh, Masahito Irie, Ayumi Matsuzawa, Mie Naruse, Toru Suzuki, Yuichi Hiraoka, Tomoko Kaneko-Ishino. Retrovirus-Derived RTL9 Plays an Important Role in Innate Antifungal Immunity in the Eutherian Brain. International Journal of Molecular Sciences. 2023. 24. 19. 14884-14884
Yoshifumi Fujioka, Hirosuke Shiura, Masayuki Ishii, Ryuichi Ono, Tsutomu Endo, Hiroshi Kiyonari, Yoshikazu Hirate, Hikaru Ito, Masami Kanai-Azuma, Takashi Kohda, et al. Targeting retrovirus-derived Rtl8a and 8b causes late onset obesity and neurodevelopmental defects. 2023
Hirosuke Shiura, Moe Kitazawa, Fumitoshi Ishino, Tomoko Kaneko-Ishino. Roles of retrovirus-derived PEG10 and PEG11/RTL1 in mammalian development and evolution and their involvement in human disease. Frontiers in cell and developmental biology. 2023. 11. 1273638-1273638

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MISC (235)：

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Patents (1)：

心臓オルガノイド及びその製造方法

Books (8)：

ゲノムインプリンティング「ポストシーケンスのゲノム科学」
ゲノムから個体へー生命システムの理解へー 2001
Genomic imprinting; Genome science in post-genomie sequenceing era.
2001
インプリンティング遺伝子の体系的同定法について。
フロンティアインモレキュラーバイオロジー 1997
Systematic approaches for identifiring imprinted genes
Frontiers in Molecular Biology 1997
Micro-/Anophthalmia observed in mouse families administered with 5-Azacytidine. J. Toxicol. Pathol.
1994

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Education (4)：

- 1983 The University of Tokyo
- 1983 The University of Tokyo Graduate School, Division of Science
- 1978 The University of Tokyo Faculty of Science
- 1978 The University of Tokyo Faculty of Science

Professional career (1)：

理学博士 (東京大学大学院理学系研究科)

Work history (5)：

2021/04 - 現在 Tokyo Medical and Dental University Institute of Research adjunct lecturer
2003/06 - 2021/03 Tokyo Medical and Dental University Medical Research Institute Professor
2014/04 - 2020/03 Tokyo Medical and Dental University Medical Research Institute Director
2015/04 - 2018/03 Japan Society for the Promotion of Science
1991 - Tokyo Institute of Technology

Awards (4)：

1998 - 戦略的基礎研究(CREST)
1996 - 日英国際共同研究
1995 - さきがけ研究21
1989 - 日本農芸化学会奨励賞

Association Membership(s) (4)：

The Japanese Society for Epigenetics , 日本農芸化学会 , 日本生化学会 , 日本分子生物学会

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