Rchr
J-GLOBAL ID：200901016370744914   Update date: Aug. 01, 2024

MOTOKO SASAKI

ササキ モトコ | MOTOKO SASAKI
Affiliation and department：
Kanazawa University Institute of Medical,Pharmaceutical and Health Sciences, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Faculty of Medicine

About Kanazawa University Institute of Medical,Pharmaceutical and Health Sciences, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Faculty of Medicine


Job title： Associate Professor
Research field  (1)： Human pathology
Research keywords  (1)： Pathology of the hepatobiliary diseases; primary biliary cholangitis (cirrhosis), Cholangiocarcinoma
Research theme for competitive and other funds  (20)：
  • 2022 - 2025 老化細胞を標的とした原発性胆汁性胆管炎の新しい治療法開発
  • 2018 - 2021 Development of new therapy for liver disease by regulating cellular senescence
  • 2015 - 2018 Involvement of dysregulated autophagy in autoimmune diseases
  • 2012 - 2015 Novel approach to primary biliary cirrhosis putting focus on deregulated autophagy
  • 2009 - 2011 Novel approach to liver disease from aspect of cellular senescence
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Papers (366)：
  • Motoko Sasaki, Yasunori Sato, Yasuni Nakanuma. Expression of fibroblast growth factor receptor 2 (FGFR2) in combined hepatocellular-cholangiocarcinoma and intrahepatic cholangiocarcinoma: clinicopathological study. Virchows Archiv. 2024. 484. 6. 915-923
  • Motoko Sasaki, Yasunori Sato, Yasuni Nakanuma. Nestin may be a candidate marker for differential diagnosis between small duct type and large duct type intrahepatic cholangiocarcinomas. Pathology - Research and Practice. 2024. 253. 155061-155061
  • 金 守良, 金 秀基, 小林 久人, 奥田 豊一, 中井 敦史, 藤井 友実, 早雲 孝信, 佐々木 素子, 狛 雄一朗, 朝井 章, et al. 病理組織学的なMetastatic carcinomatous cirrhosisをきたした浸潤性小葉癌の1症例. 肝臓. 2023. 64. 11. 575-582
  • Soo Ryang Kim, Soo Ki Kim, Yu-Ichiro Koma, Motoko Sasaki, Akira Asai, Hiroki Nishikawa. Hepatic Inflammatory Pseudotumor-Focusing on Its Heterogeneity. Diagnostics (Basel, Switzerland). 2023. 13. 17
  • Motoko Sasaki, Yasunori Sato, Yasuni Nakanuma. Bile duct adenoma and small-sized small duct type intrahepatic cholangiocarcinoma show distinct differences in genetic alterations, expression of IMP3 and EZH2 and stromal and inflammatory components. Histopathology. 2023. 83. 2. 298-309
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MISC (150)：
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Books (22)：
  • 胆道疾患を診る医師のための胆道病理テキスト
    南江堂, 東京 2015
  • 胆道疾患を診る医師のための胆道病理テキスト
    南江堂, 東京 2015
  • 胆道疾患を診る医師のための胆道病理テキスト
    南江堂, 東京 2015
  • C型肝炎の診療を極める。〜基本から最前線まで〜
    文光堂, 東京 2014
  • 専門医のための消化器病学 第2版
    2013
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Lectures and oral presentations  (48)：
  • Enhanced VASH1 expression in splenic sinus lining cells relates to splenomegaly in IPH
    (The Asian Pacific Association for the Study of the Liver (APASL) 2016 Tokyo 2016)
  • Bile acids and cholangiocyte autophagy
    (The XXIV International Bile Acid Meeting“Bile Acids in Health and Disease”. Düsseldorf 2016)
  • ARID 1A mutations may represent a novel pathway of carcinogenesis in biliary carcinomas.
    (The 66th Annual meeting of American Association for the Study of Liver Diseases (AASLD). San Francisco 2015)
  • Increased expression of ORM1-like protein 3 (ORMDL3) in biliary epithelial cells may be related to the pathogenesis of primary biliary cirrhosis.
    (The 66th Annual meeting of American Association for the Study of Liver Diseases (AASLD). San Francisco 2015)
  • Recent Advances in Liver Pathology. Cholangiocarcinoma and precursor lesions: An involvement of cellular senescence in cholangiocarcinogenesis.
    (The Annual Meeting of GEST 2015)
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Education (2)：
  • 1989 - Kanazawa University Graduate School, Division of Medicine
  • - 1988 Kanazawa University
Professional career (1)：
  • 医学博士
Committee career (10)：
  • 2016/04 - 現在 日本肝臓学会 評議員
  • 2014/04 - 現在 日本臨床細胞学会 評議員
  • 2014/04 - 現在 日本胆道学会 評議員
  • 2013/04 - 現在 日本肝癌研究会 幹事
  • 1996 - 現在 日本病理学会 日本病理学会 評議員
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Awards (6)：
  • 2017/12 - はあざみ女性研究者賞 (紫花賞)
  • 2017/09 - 北國がん基金「北國がん基金研究助成」
  • 金沢市医師会 金沢医学館記念医学賞 (2009)
  • 日本病理学会学術研究賞 (2009)
  • 北國がん基金 北國がん基金研究助成 (2006)
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Association Membership(s) (8)：
American Association for the study of liver diseases(AASLD) ,  日本組織細胞化学会 ,  International Academy of Pathology (IAP) ,  日本臨床細胞学会 ,  日本肝癌研究会 ,  日本胆道学会 ,  日本肝臓学会 ,  日本病理学会
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