Rchr
J-GLOBAL ID：200901016458544320   Update date: Aug. 07, 2024

Kawano Tomikazu

カワノ トミカズ | Kawano Tomikazu
Affiliation and department：
Iwate Medical University School of Pharmacy

About Iwate Medical University School of Pharmacy


Research field  (6)： Pharmaceuticals - chemistry and drug development ,  Biochemistry ,  Inorganic and coordination chemistry ,  Bioorganic chemistry ,  Structural/physical organic chemistry ,  Molecular biochemistry
Research keywords  (4)： 有機合成化学 ,  ケミカルバイオロジー ,  医薬品化学 ,  Supramolecular Chemistry
Research theme for competitive and other funds  (8)：
  • 2023 - 2024 Development and application of stereoselective synthesis of cyclopropane fused heteropolycyclic compounds
  • 2013 - 2016 Molecular action mechanisms of chemical compounds that induce non-proteasomal degradation of beta-catenin
  • 2011 - 2012 Wntシグナル伝達経路を標的とする新規大腸がん治療薬の開発
  • 2008 - 2010 連続型マイクロフローシステムによる触媒的不斉Morita-Baylis-Hillman反応の開発
  • 2003 - 2005 Chemogenomic approach for elucidation and control of intracellular signal transductions
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Papers (56)：
  • Tetsuya Tsujihara, Koki Nishino, Wakaba Miura, Ayumi Chiba, Wakana Hayashi, Chika Yoshida, Tsunayoshi Takehara, Takeyuki Suzuki, Tomikazu Kawano. Enantioselective One-Pot Synthesis of Cyclopropane-Fused Tetrahydroquinolines via a Ru-Catalyzed Intramolecular Cyclopropanation. Organic Letters. 2024
  • Sho Inagaki, Riko Omichi, Kei Yamazaki, Yuzuka Shibuta, Tomikazu Kawano. Synthesis of 5-Amino-3(2H)-furanones via S-Methylation/Intramolecular Cyclization of γ-Sulfanylamides. The Journal of organic chemistry. 2024. 89. 10. 6770-6782
  • Hiroshi Katagiri, Honami Yonezawa, Sho Shitamura, Aoi Sugawara, Tomikazu Kawano, Makoto Maemondo, Naoyuki Nishiya. A Wnt/β-catenin signaling inhibitor, IMU1003, suppresses the emergence of osimertinib-resistant colonies from gefitinib-resistant non-small cell lung cancer cells. Biochemical and biophysical research communications. 2023. 645. 24-29
  • Tetsuya Tsujihara, Tomikazu Kawano, Keigo Sato, Sho Inagaki, Tsunayoshi Takehara, Takeyuki Suzuki. Catalytic Enantioselective Construction of trans-Fused 2,3,3a,4,5,9b-Hexahydro-1H-pyrrolo[3,2-c]quinoline Derivatives by Intramolecular [3+2]-Cycloaddition. HETEROCYCLES. 2023. 106. 2. 336-336
  • Tetsuya Tsujihara, Ryota Sasaki, Mizuki Fukkoshi, Sae Hatakeyama, Tsunayoshi Takehara, Takeyuki Suzuki, Tomikazu Kawano. Synthesis of 6,7-benzene-fused tropane derivatives from isoindoline-aminal hybrid compound. Tetrahedron Letters. 2022. 95. 153724-153724
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MISC (106)：
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Patents (2)：
Books (1)：
  • 薬系有機化学
    南江堂 2018
Lectures and oral presentations  (2)：
  • A New Method for the Preparation of Fluorenol Derivatives by Domino Radical Cyclization of Simple Acyclic Polyynes
    (Proceedings of 2nd SANKEN International Symposium 1999)
  • Diastereoselective Formation of P and M Tricopper(I) Triple-Stranded Helciates with Chiral Ethynylpyridine Ligands
    (Proceedings of 2nd SANKEN International Symposium 1999)
Works (7)：
  • 連続的連続型マイクロフローシステムによる触媒的不斉Morita-Baylis-Hillman反応の開発
    2008 -
  • 細胞内信号伝達経路の解明と制御に対する Chemogenomic アプローチ
    2004 -
  • タンパク質発現システム
    2004 -
  • Chemical genomic アプローチによる細胞内信号伝達経路の解明に関する調査研究
    2004 -
  • 21世紀COEプログラム“新産業創造指向インターナノサイエンス”
    2003 -
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Education (4)：
  • - 1996 大阪大学大学院 理学研究科 有機化学
  • - 1996 Osaka University Graduate School, Division of Natural Science Organic Chemistry
  • - 1991 Osaka University School of Science
  • - 1991 Osaka University Faculty of Science Organic Chemistry
Professional career (2)：
  • Doctor of Science (Osaka University)
  • Master of Science (Osaka University)
Work history (5)：
  • 2021/04 - 現在 Iwate Medical University School of Pharmacy
  • 2014/04 - 現在 Iwate Medical University School of Pharmacy
  • 2018/04 - 2021/03 Iwate Medical University School of Pharmacy
  • 2007/04 - 2014/03 Iwate Medical University School of Pharmacy
  • 1996/04 - 2007/03 Osaka University The Institute of Scientific and Industrial Research
Committee career (2)：
  • 2019/02 - 現在 公益社団法人日本薬学会 代議員
  • - 現在 日本私立薬科大学協会 薬剤師国家試験問題検討委員会物理・化学・生物部会
Awards (4)：
  • 2008 - 2007年度(第20回)有機合成化学協会研究企画賞(住友化学研究企画賞)
  • 2003 - BCSJ賞
  • 1999 - 日本化学会第76春季年会(1999)ポスター賞
  • 1999 - Poster Prize Award, the 76th Annual Meeting of The Chemical Society of Japan
Association Membership(s) (10)：
THE JAPANESE CANCER ASSOCIATION ,  THE JAPANESE ASSOCIATION FOR MOLECULAR TARGET THERAPY OF CANCER ,  岩手ネットワークシステム ,  JAPANESE SOCIETY FOR CHEMICAL BIOLOGY ,  THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY ,  日本化学会 ,  日本薬学会 ,  Kinki Chemical Society, Japan ,  The Pharmaceutical Society of Japan; ,  The Chemical Society of Japan;
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