Kato Tadafumi

Affiliation and department：
Job title：主任教授
Homepage URL (2)： https://www.juntendo.ac.jp/hospital/clinic/mental/about/staff.html , https://www.juntendo-molecular-psychiatry.com/en/members/

Research field (1)： Psychiatry

Research keywords (19)：脳・神経 , ミトコンドリアDNA , 遺伝子多型 , 脳画像 , 双極性障害(躁うつ病) , 動物モデル , 一卵性双生児不一致例 , 脳エネルギ-代謝 , ミトコンドリア , 統合失調症 , 精神疾患 , BDNF , WFS1 , 遺伝子発現 , XBP1 , 小胞体ストレス , 磁気共鳴スペクトロスコピ- , 躁うつ病 , 双極性障害

Research theme for competitive and other funds (35)：

2023 - 2026 Development for the early diagnostic marker for schizophrenia using the ability of NMDA receptor subunit switching
2022 - 2025 Significance of somatic mutations in bipolar disorder
2020 - 2023 双極性障害トリオ試料におけるポリジェニックリスクスコアを用いた画像ー遺伝子研究
2018 - 2023 マルチスケール精神病態の構成的理解(総括班)
2018 - 2023 Constructive understanding of bipolar disorder and schizophrenia by transomics and modeling

2017 - 2022 Role of paraventricular thalamic nucleus in bipolar disorder

2015 - 2018 Analysis of LINE-1 retrotransposition using poly(I:C) animal model

2015 - 2018 Detection of novel LINE-1 insertion in prefrontal cortex of patients with schizophrenia

2015 - 2018 Development of techniques for analyzing somatic mutations in single neurons of psychiatric disorders

2015 - 2017 Analysis of iPS cell-derived Neural Cells from Monozygotic Twins Discordant for Bipolar Type Schizoaffective Disorder

2012 - 2017 Structural plasticity of neurons associated with depressive state and its pathophysiological significance

2012 - 2017 Unraveling the micro-endophenotypes of psychiatric disorders at the molecular, cellular and circuit levels

2012 - 2017 Elucidation of causative neural circuit of bipolar disorder

2010 - 2016 Comprehensive Brain Science Network

2009 - 2011 Elucidating gene X environment interaction in the pathophysiology of schizophrenia using twin research

2009 - 2011 Neural network development disorder as a cause of cognitive/behavioral impairment in childhood. mental function and neural stem cell transplantation

2009 - 2010 高速シーケンスによる一卵性双生児双極性障害不一致例における遺伝子変異の探索

2008 - 2009 Role of endoplasmic reticulum stress pathway in bipolar disorder

2006 - 2009 Development of a diagnostic test of bipolar disorder using gene expression analysis

2005 - 2009 A Search for Risk Genes of Psychiatric Disorders

2006 - 2007 双極性障害における小胞体ストレスおよびミトコンドリア機能障害の意義についての研究

2006 - 2007 The possible implication of fetal alcohol exposure on the behavioral abnormalities in the young adult.

2005 - 2005 双極性障害における神経細胞機能障害の検討

2004 - 2005 Role of XBP1 in neurons

2004 - 2005 The alteration of adult neural network by pre/post-natal alcohol and addictive drug exposure

2003 - 2004 A study for clinical significances of the polymorphisms of mitochondria-related genes in bipolar disorder.

2002 - 2003 The post-genomic research for the pathophysiology and treatment of alcohol and drug addictions.

2001 - 2003 An investigation of the involvement of methylation in the parhogenesis of mental diseases by differential genomic analyses of monozygotic twins discordant for the diseases.

2002 - 2002 感情制御とその障害に関する脳科学研究

2001 - 2002 Identification of candidate genes for bipolar disorder and schizophrenia using DNA microarray

1999 - 2000 双極性障害におけるミトコンドリア機能障害に関する分子生物学的研究

1998 - 1999 A STUDY OF POLYMORPHISM IN THE HUMAN DOPAMlNE D2 AND D4 RECEPTOR GENE AND CLINICAL FEATURE IN AUTISTIC SUBJECTS.

1997 - 1998 双極性障害における細胞内pH低下と白質高信号についての研究

1995 - 1997 Brain metabolism in bipolar patients measured by Magnetic resonance spectroscopy

1993 - 1993 化学シフトイメージングを用いた躁うつ病の脳内エネルギー代謝の研究

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Papers (441)：

Hidetaka Tamune, Hirohisa Fujikawa, Hiroyuki Harada, Tomoyuki Kodama, Masaaki Sasaki, Daichi Sone, Miwa Sekine, Masanobu Ito, Tadafumi Kato, Yuji Nishizaki, et al. Integrating psychiatry into basic clinical skills: A three-year nationwide quantitative assessment of postgraduate training programs. Psychiatry and Clinical Neurosciences Reports. 2024. 3. 4
Akane Yoshikawa, Youhei Obata, Chihiro Kakiuchi, Atsushi Nakanishi, Satoshi Kimura, Shigeki Aoki, Tadafumi Kato. Case series of patients with early psychosis presenting hypoperfusion in angular gyrus and self-disturbance: Implication for the sense of agency and schizophrenia. Neuropsychopharmacology reports. 2024
Tadafumi Kato, Kazuyoshi Ogasawara, Keisuke Motomura, Masaki Kato, Teruaki Tanaka, Yoshikazu Takaesu, Shintaro Nio, Taro Kishi, Mirai So, Kiyotaka Nemoto, et al. Practice Guidelines for Bipolar Disorder by the JSMD (Japanese Society of Mood Disorders). Psychiatry and clinical neurosciences. 2024
Takumi Nakamura, Toru Yoshihara, Chiharu Tanegashima, Mitsutaka Kadota, Yuki Kobayashi, Kurara Honda, Mizuho Ishiwata, Junko Ueda, Tomonori Hara, Moe Nakanishi, et al. Transcriptomic dysregulation and autistic-like behaviors in Kmt2c haploinsufficient mice rescued by an LSD1 inhibitor. Molecular psychiatry. 2024
齋藤友貴, 藤村俊雅, 平大樹, 高橋啓太郎, 平田友恵, 薬師川直人, 清水健太郎, 永野友理恵, 藤本一馬, 吉成尚人, et al. 双極性障害立て直し入院における診断の変化. 精神神経学雑誌. 2024. 126. 3. 226-226

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MISC (221)：

永倉暁人, 河上緒, 大島健一, 新里和弘, 加藤忠史, 水野雅文. せん妄を伴ったレビー小体型認知症の一剖検例. 精神神経学雑誌. 2022. 124. 4付録. S-385
伊藤賢伸, 長谷川由果子, 金城智也, 鈴木利人, 加藤忠史. Effect of digoxin on the expression of ASD-related genes. 日本臨床精神神経薬理学会プログラム・抄録集. 2021. 31st
Tadafumi Kato, Mie Kubota-Sakashita, Tomoaki M. Kato. Reply to “Correspondence to Ant1 mutant mice bridge the mitochondrial and serotonergic dysfunctions in bipolar disorder”. Molecular Psychiatry. 2020. 25. 10. 2205-2206
From genome to ion : toward biological understandings of bipolar disorder. 2019. 51. 14. 710-713
阿竹聖和, 越川陽介, 井形亮平, 富永裕崇, 小西勇輝, 香月あすか, 堀輝, 板東宏樹, 坂井志帆, 西田圭一郎, et al. 血中サイトカイン濃度はミルタザピンとSSRIの治療反応に異なって寄与し得るか GUNDAM studyより. 日本臨床精神神経薬理学会・日本神経精神薬理学会合同年会プログラム・抄録集. 2019. 29回・49回. 153-153

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Books (23)：

双極性障害 : 双極症I型・II型への対処と治療
筑摩書房 2019 ISBN:9784480072283
双極性障害 : 病態の理解から治療戦略まで
医学書院 2019 ISBN:9784260039178
臨床脳科学 (脳と心のライブラリー)
岩崎学術出版社 2018 ISBN:4753311368
臨床脳科学 : 心から見た脳
岩崎学術出版社 2018 ISBN:9784753311361
これだけは知っておきたい双極性障害 : 躁・うつに早めに気づき再発を防ぐ!
翔泳社 2018 ISBN:9784798157139

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Professional career (1)：

医学博士

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