Okamoto Takayuki

2020 - 2023 非アルコール性脂肪性肝疾患において発現が増加するmiRNAの機能解析

2019 - 2022 Molecular mechanism of cooperation between endothelial cell stiffness and functions.

2019 - 2022 Development of a prediction system of systemic disease using AI technology based on oral flora.

2018 - 2021 Establishment of evaluation method for arteriosclerotic lesions by measuring the "hardness" of blood vessels using an atomic force microscope

2016 - 2019 The role of gap junction-mediated regulation of endothelial cellular stiffness

2016 - 2019 The peritoneum omentum exosomes in the septic immune paralysis

2016 - 2019 Proof of concept study of a novel excess chromosome elimination therapy to ameliorate and prevent trisomy 21 associated complications

2016 - 2019 Basic study on anti-tumor activity of non-vitamin K dependent oral anticoagulants (NOACs)

2016 - 2018 Interaction between beta2 integrin and thrombomodulin effect to immunothrombosis

2016 - 2018 Establishment of diagnostic method for leaky gut syndrome using mice model.

2016 - 2018 The ability of human extracellular vesicles to augment inflammatory host response in septic shock

2014 - 2016 Analysis of the interaction between neutrophil and thrombomodulin.

2013 - 2016 Endothelial cellular gap junctions regulate the vascular angiogenesis

2013 - 2016 Molecular pathological studies on the effect of anticoagulant protein C pathway on the regulation of tumorgenesis

2012 - 2015 Aberrant activation of interns in the pathogenesis of immune diseases

2011 - 2012 Analysis of tumor protein in acidic condtion and Development of magnetic hyperthermia for tumor acidic target

2010 - 2011 Regulation of endothelial cell functions by anticoagulant factors and gap junction.

2009 - 2011 Studies on Molecular-Cellular Mechanisms of Protein C Anticoagulant Pathway Crucial for Life Homeostasis

2007 - 2008 Functional analysis of gap junction protein connexin32 in endothelial cells

2007 - 2008 Studies on Molecular-Cellular Mechanisms of Protein C AnticoagulantPathway Crucial for Life Maintenance

2006 - 2007 Mechanism of inhibitory effect of protein C inhibitor on tumorigenesis and angiogenesis

2005 - 2006 血管障害性疾患に対する新規なリスク分子・標的治療分子の探索研究

2005 - 2006 Molecular pathobiological studies on anti-coagulant protein C pathway which is essential for the vital functions

2004 - 2005 Effect of protein C inhibitor on renal cell carcinogenesis and on tumor invasion, growth and metastasis

2004 - Search of a new anti-thrombosis molecule

血管内皮細胞における細胞間相互作用の解析

血管内皮細胞のメカノバイオロジーの解明

炎症と血液凝固のクロストークの解明