Rchr
J-GLOBAL ID:200901018543916662   Update date: Nov. 18, 2024

Kasuya Yoshitoshi

Kasuya Yoshitoshi
Affiliation and department:
Other affiliations (1):
Research field  (2): Pharmacology ,  Respiratory medicine
Research keywords  (8): Cell Differentiation/Dedifferentiation ,  Pulmonary Fibrosis ,  Neural Stem Cells ,  p38 mitogen-activated protein kinase ,  Inflammatory Pulmonary Diseases ,  Intracellular Signaling ,  Molecular Pharmacology ,  Molecular and Cellular Biochemistry
Research theme for competitive and other funds  (43):
  • 2013 - 2025 新規細胞培養とその応用に関する研究
  • 2019 - 2022 難治性呼吸器疾患の治療法探索に向けた包括的解析
  • 2018 - 2019 線維化肺の再生治療に向けた包括的研究
  • 2016 - 2019 特発性肺線維症治療薬の探索
  • 2013 - 2017 Functional roles of arginine methylation on vascular networks for nutritional supply
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Papers (100):
  • Asako Yanagisawa, Jun-Dal Kim, Akira Naito, Takayuki Kobayashi, Tomoko Misawa, Seiichiro Sakao, Takayuki Jujo-Sanada, Takeshi Kawasaki, Shin-Ichi Muroi, So-Ichiro Sasaki, et al. Deciphering the inhibitory effects of trimetazidine on pulmonary hypertension development via decreasing fatty acid oxidation and promoting glucose oxidation. Scientific reports. 2024. 14. 1. 27069-27069
  • Eon Kurumiya, Mayuu Iwata, Yoshitoshi Kasuya, Koichiro Tatsumi, Takuya Honda, Toshihiko Murayama, Hiroyuki Nakamura. Eliglustat exerts anti-fibrotic effects by activating SREBP2 in TGF-β1-treated myofibroblasts derived from patients with idiopathic pulmonary fibrosis. European journal of pharmacology. 2024. 966. 176366-176366
  • Tadasu Okaya, Takeshi Kawasaki, Shun Sato, Yu Koyanagi, Koichiro Tatsumi, Ryo Hatano, Kei Ohnuma, Chikao Morimoto, Yoshitoshi Kasuya, Yoshinori Hasegawa, et al. Functional Roles of CD26/DPP4 in Bleomycin-Induced Pulmonary Hypertension Associated with Interstitial Lung Disease. International journal of molecular sciences. 2024. 25. 2
  • Hiroyuki Nakamura, Yuan Zhou, Yuka Sakamoto, Ayako Yamazaki, Eon Kurumiya, Risa Yamazaki, Kyota Hayashi, Yoshitoshi Kasuya, Kazuaki Watanabe, Junya Kasahara, et al. N-butyldeoxynojirimycin (miglustat) ameliorates pulmonary fibrosis through inhibition of nuclear translocation of Smad2/3. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023. 160. 114405
  • Yu Koyanagi, Takeshi Kawasaki, Yoshitoshi Kasuya, Ryo Hatano, Shun Sato, Yukiko Takahashi, Kei Ohnuma, Chikao Morimoto, Steven M Dudek, Koichiro Tatsumi, et al. Functional roles of CD26/DPP4 in bleomycin-induced pulmonary fibrosis. Physiological reports. 2023. 11. 6. e15645
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MISC (75):
  • Koyanagi Yu, Kawasaki Takeshi, Kasuya Yoshitoshi, Hatano Ryo, Suzuki Takuji. CD26/DPP4欠損マウスではブレオマイシン誘発肺線維症が抑制される(Bleomycin-induced pulmonary fibrosis is attenuated in CD26/DPP4 deficient mice). 日本呼吸器学会誌. 2023. 12. 増刊. 370-370
  • Koyanagi Yu, Kawasaki Takeshi, Kasuya Yoshitoshi, Hatano Ryo, Suzuki Takuji. Bleomycin-induced pulmonary fibrosis is attenuated in CD26/DPP4 deficient mice(タイトル和訳中). 日本呼吸器学会誌. 2023. 12. 増刊. 370-370
  • 見上 英樹, 吉岡 健人, 鈴木 健一, 鵜飼 啓太, 幡野 雅彦, 巽 浩一郎, 粕谷 善俊. 新規肺線維症モデルマウスの構築. 日本獣医学会学術集会講演要旨集. 2018. 161回. 433-433
  • Iliroki Umezawa, Yusuke Naito, Kensuke Tanaka, Kento Yoshioka, Tatsuhiko Sudo, Masahiko Hagihara, Masahiko Hatano, Koichiro Tatsumi, Yoshitoshi Kasuya. Inhibition of p38 alpha improved functional outcome in a mouse model of spinal cord injury: the involvement of p38 alpha in tissue regeneration. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2017. 133. 3. S130-S130
  • Kento Yoshioka, Kana Namiki, Tatsuhiko Sudo, Yoshitoshi Kasuya, Masahiko Hatano. In vitro expansion of neural stem cells derived from the adult hippocampus. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2017. 133. 3. S113-S113
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Patents (2):
  • Method for inhibiting differentiation of neural stem cell, method for preparing neural stem cell, and method for differentiating and inducing neural stem cell
  • Neural stem cells having increased passage ability, method for producing neural stem cells having increased passage ability, and method for culturing neural stem cells for increasing passage ability of neural stem cells
Books (6):
  • 脳の損傷と再生に関わるシグナル伝達-循環ペプチド因子の病態生理学的役割-
    わかる脳と神経(羊土社) 2009
  • Human Biology/5th Ed. (Daniel D Chris)
    2007
  • Endothelin in regulation of vascular tone
    Raven Press, New York 1993
  • 「血管拡張、収縮作用をもつ新しいペプチド」(共著)
    血管の機能と障害(藤田企画出版) 1991
  • A hypothesis for mechanism of endothelin-induced vasoconstriction
    1991
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Lectures and oral presentations  (15):
  • かゆみの情報伝達に寄与する神経基盤と慢性掻痒病態における機能変化
    (第5回下総薬理学研究会 2024)
  • 学術論文出版セミナー: 論文の構成と書き方 - 投稿から掲載まで論文著者が知っておくべきポイント
    (Wiley APAC Japan Webinar 公開招待講演 2024)
  • セボフルラン麻酔下の睡眠関連神経ペプチドの上気道開大筋への効果
    (第97回日本薬理学会年会 2023)
  • 患者由来の筋線維芽細胞を用いた新規肺線維症治療法の探索
    (第97回日本薬理学会年会 2023)
  • シンポジウム:呼吸器疾患研究 -最近の進展- <肺線維症の治療ターゲット探索に向けた実験モデルシステムの開発>
    (第94回日本生化学会大会 2021)
more...
Education (3):
  • 1987 - 1990 University of Tsukuba Graduate School of Medicine Program of Biochemistry
  • 1985 - 1987 University of Tsukuba Master's Program in Medical Sciences Medical Sciences
  • 1981 - 1985 Tokyo University of Science Faculty of Pharmaceutical Sciences Department of Pharmacy
Professional career (1):
  • (BLANK) (University of Tsukuba)
Work history (7):
  • 2024/04 - 現在 Chiba University Graduate School of Medicine Professor
  • 2024/04 - 現在 Juntendo University Faculty of Pharmacy Professor
  • 2007/04 - 2024/03 Chiba University Graduate School of Medicine Associated Professor
  • 1999/10 - 2007/03 Chiba University School of Medicine Associated Professor
  • 1991/08 - 1999/10 University of Tsukuba Basic Medical Sciences Assistant Professor
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Committee career (5):
  • 2022/10 - 現在 日本薬理学会 代議員
  • 1999/10 - 現在 千葉医学会 評議員
  • 1991/12 - 現在 日本薬理学会 評議員
  • 2016/10 - 2018/09 日本薬理学会 代議員
  • 2012/10 - 2014/09 日本薬理学会 代議員
Association Membership(s) (5):
The Pharmaceutical Society of Japan ,  American Society of Biochemistry and Molecular Biology ,  千葉医学会 ,  日本生化学会 ,  日本薬理学会
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