Research theme for competitive and other funds (18)：
2020 - 2023 Environmental pollutant degradation system using dye-decolorizing peroxidase
2019 - 2021 Molecular Design and Functional Regulation of Integrated Membrane-bound Protein Using Nono-disc
2016 - 2019 Dynamic Structural Characterization of Electron Transfer Complex in Respiratory Chain of Mitochondria and Its Electron Transfer Regulation Mechanism
2016 - 2019 病原菌に特徴的な鉄の取り込みタンパク質に着目した新規な抗菌剤の開発
2015 - 2018 Analysis of functional regulation of PGMRC1
2013 - 2016 Functional and Structural Characterization of Electron Transfer Reactions in Mitochondria Respiratory Chain Utilizing Nanodisc
2013 - 2015 Structural Characterization of Subunit-Specific Isotope labelled Membrane Bound Protein
2012 - 2014 Characterization of the proteins involved in iron uptake system of pathogen and its application to development of anti-bacterial drugs
2011 - 2012 Analysis of Interactions in High Molecular Weight Protein Complexes by Using Segment Label and Cutting-edge NMR Technologies
2009 - 2011 Structural Characterization of Heme-mediated Signaling Mechanism in Protein Regulation System
2008 - 2010 Redox- and CO-dependent Transcription Mechanism by NPAS2
2002 - 2006 Development of Detection Methods of Dynamical Higher Order Structures of Proteins and Its Application to Elucidation of Structure-Function Relations of Proteins.
Takeshi Uchida, Sayaka Umetsu, Miho Sasaki, Haruka Yoshimura, Issei Omura, Koichiro Ishimori. A dye-decolorizing peroxidase from Vibrio cholerae can demetallate heme. Journal of Inorganic Biochemistry. 2024. 112764-112764
Issei Omura, Koichiro Ishimori, Takeshi Uchida. Converting cytochrome c into a DyP-like metalloenzyme. Dalton Transactions. 2022. 51. 33. 12641-12649
Takeshi Uchida, Kazuki Ota, Akinobu Tatsumi, Syota Takeuchi, Koichiro Ishimori. Metal Sensing by a Glycine-Histidine Repeat Sequence Regulates the Heme Degradation Activity of PM0042 from Pasteurella multocida. Inorganic Chemistry. 2022. 61. 34. 13543-13553
Dayeon Nam, Wataru Motegi, Koichiro Ishimori, Takeshi Uchida. Heme binding to cold shock protein D, CspD, from Vibrio cholerae. Biochemical and Biophysical Research Communications. 2022. 624. 151-156
Kazuyoshi Muranishi, Koichiro Ishimori, Takeshi Uchida. Regulation of the expression of the nickel uptake system in Vibrio cholerae by iron and heme via Fur. Journal of Inorganic Biochemistry. 2022. 111713-111713
大村翼世, 石森浩一郎, 内田毅. The activity control of dye-decolorizing peroxidase (DyP) by conversion of the optimal pH. 金属の関与する生体関連反応シンポジウム講演要旨集. 2018. 28th (Web)
