Ono Minoru

オノミノル | Ono Minoru

Affiliation and department：
Job title： Professor
Other affiliations (1)：

東大病院医工連携部部長

Research field (1)： Cardiovascular surgery

Research keywords (10)：僧帽弁形成術 , 心拍動下冠状動脈手術 , 心臓移植 , 補助人工心臓 , ロボット心臓手術 , Mitral valve repair , Heart transplantation , Ventricular assist device , Minimally invasive surgery , Robotic Surgery

Research theme for competitive and other funds (33)：

2023 - 2027 Optimizing biocompatibilities of an artificial lung in a setting of a long-term pulmonary artery-left atrium (PA-LA) extracorporeal circulation system
2022 - 2025 植込型補助人工心臓患者における血栓・出血合併症の新予測システム確立に関する研究
2022 - 2025 心内膜の線維化に着眼した心線維化メカニズムの解明とその治療法の開発
2019 - 2023 心内膜の線維化に着眼した心線維化メカニズムの解明とその治療法の開発
2015 - 2018 Lanthanum carbonate inhibits aortic allograft calcification in circulatory transplant models

2014 - 2018 Comprehensive study for practical use of a total implantable total artificial heart with small size and high performance.

2013 - 2015 結紮を必要としない微細縫合糸の開発に関する前臨床試験

2010 - 2015 Clinical Trial of Berlin Heart Excor Pediatric

2010 - 2014 Comprehensive study of an implantable total artificial heart using continuous flow blood pump

2011 - 2013 Animal implant research on small suturing device which eliminates knot tying

2011 - 2013 Phosphate binders inhibit calcification of aortic and cardiac valve allografts.

2010 - 2012 慢性虚血性心疾患に対する在宅体外式カウンターパルセーション治療の有効性の検討

2008 - 2012 手術用ロボットシステムの開発と臨床応用

2009 - 2011 Construction of the heart rehabilitation system by the assisted artificial heart which aimed at the cardiac functional recovery of serious heart failure

2005 - 2008 Basic study for implantable non-pulsatile total artificial heart

2004 - 2005 臍帯血幹細胞移植を用いた再生医療的技術による心筋梗塞治療法の開発

2002 - 2004 Clinical and experimental research on prolongation of durability of cryopreserved allogeneic heart valve and vessel

2002 - 2004 Development of prosthetic valve with self expanding suture seat.

1999 - 2001 Development of auto-swelling vascular grafts using superabsorbent polymer

1999 - 2001 Newly developed auto-swelling vascular grafts for endovascular repair

1998 - 1999 Studies on the cellular modulation in cryopreservation focusing the allogenicity of thoracic tissues

1997 - 1999 Studies on the implantation of the heart valves or great vessels utilizing viable xeno-tissues

1997 - 1998 胸腺腫のリンパ球誘導・分化阻害機構の基礎的研究

1997 - 1998 凍結保存が血管内皮細胞の抗原性に及ぼす影響についての基礎的研究

1997 - 1998 Basic and Clinical study on Percutaneous Endovascular Surgery With Ultrathin-wall Vascular Grafts

1994 - 1996 Development of the new monitoring system for acute rejection in clinicallung and lung-heart transplantation, focusing on the cytotoxicity specific to the major histocompatibility complex class I antigens of the donor organ.

1995 - 1995 同種肺移植拒絶反応における臓器特異的抗原の基礎的研究

1994 - 1995 RESEARCH ON HUMAN AIRWAY EPITHELIUM ACTING AS ALLOANTIGEN-PRESENTING CELLS

補助人工心臓離脱を可能とするために臨床研究

同種弁・血管の長期生着率向上に関する研究

Clinical reaserch on weaning from left ventricular assist device after long-term support

Development and clinical application of robotic system to cardiac surgery

Development of minute suture which eliminates ligature

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Papers (485)：

Masaki Tsuji, Takahiro Kurihara, Yoshitaka Isotani, Chie Bujo, Junichi Ishida, Eisuke Amiya, Masaru Hatano, Asako Shimada, Hiroko Imai, Mitsutoshi Kimura, et al. Right heart reserve function assessed with fluid loading predicts late right heart failure after left ventricular assist device implantation. The Canadian journal of cardiology. 2024
Ryo Abe, Toshiyuki Ko, Shunsuke Inoue, Seitaro Nomura, Takahiro Jimba, Manami Katoh, Masamichi Ito, Junichi Ishida, Eisuke Amiya, Norifumi Takeda, et al. A Pathogenic LAMP2 Non-Canonical Splice Site Mutation Caused Danon Disease Requiring Heart Transplantation. Circulation journal : official journal of the Japanese Circulation Society. 2024
Yoshiaki Kanno, Koh Okamoto, Takayuki Shinohara, Osamu Kinoshita, Masaru Hatano, Mahoko Ikeda, Sohei Harada, Shu Okugawa, Kyoji Moriya, Minoru Ono, et al. Pre-Transplant Seroprevalence, Associated Factors, and Post-Transplant Incidence of Toxoplasma gondii Infection Among Heart Transplant Recipients in Japan. Transplantation proceedings. 2024
Kohsaku Goto, Toshiya Kojima, Tsukasa Oshima, Akihito Saito, Yu Shimizu, Katsura Soma, Yukiteru Nakayama, Eriko Hasumi, Ryo Inuzuka, Masahiko Ando, et al. A leadless pacemaker implantation for a patient with systemic right ventricle under ventricular assist device support. Journal of Cardiology Cases. 2024
Shinnosuke Sawano, Mizuki Miura, Yasutomi Higashikuni, Hiroyuki Saigusa, Satoshi Kodera, Norifumi Takeda, Masaru Hatano, Jiro Ando, Minoru Ono, Issei Komuro. Clinical valve thrombosis and arterial embolism in a cancer patient after transcatheter aortic valve replacement. Oxford medical case reports. 2023. 2023. 11. omad125

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MISC (148)：

縄田寛, 吉岡大輔, 小野稔, 秋山正年, 澤芳樹, 齋木佳克, 中川健, 江川裕人. 心臓臓器移植におけるAMR治療の実態とrituximab(遺伝子組換え)使用に関する全国使用実態調査の結果. 移植. 2021. 56. 1. 43-52
山崎健二, 胡盛寿, 董念国, 陳良万, 本村禎, SLAUGHTER Mark, 小野稔, 齋木佳克, 戸田宏一, 齋藤聡, et al. 国産植込型補助人工心臓EVAHEARTの海外展開. 北海道外科雑誌. 2020. 65. 1
山崎健二, 本村禎, 胡盛寿, 董念国, 陳良万, SLAUGHTER Mark, 小野稔, 齋木佳克, 戸田宏一, 齋藤聡, et al. 国産植込型補助人工心臓EVAHEARTの中国・米国展開. 人工臓器(日本人工臓器学会). 2020. 49. 2
Hiroshi Goto, Katsuhisa Matsuura, Hidekazu Sekine, Hyoe Komae, Yu Yamasaki, Daisuke Sasaki, Minoru Ono, Tatsuya Shimizu. Improvement of Relaxation Function is a Novel Index of Maturation in Human Induced Pluripotent Stem Cell-Derived Engineered Cardiomyocyte Tissues. CIRCULATION. 2019. 140
天尾理恵, 山口正貴, 藤堂太右, 柏公一, 木下修, 木村光利, 遠藤美代子, 篠田裕介, 小野稔, 芳賀信彦. 植込型補助人工心臓装着術後周術期の認知機能に関与する因子の検討. 人工臓器. 2019. 48. 2. S-11

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Education (2)：

- 1987 The University of Tokyo Faculty of Medicine
- 1987 The University of Tokyo Faculty of Medicine School of Medicine

Professional career (1)：

PhD (The University of Tokyo)

Committee career (14)：

2021/11 - 現在 International Federation for Artificial Organs Executive Board Member
2019/04 - 現在 Japan Biodesign President
2019/02 - 現在 Asian Society for Thoracic and Cardiovascular Surgery Secretary General, Executive Board Member
2013/10 - 現在 Japanese College of Angiology Executive Board member, Councilor
2012/04 - 現在 Japanese Heart Failure Society Executive Board member, Councilor

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Association Membership(s) (19)：

European Society for Cardio-Thoracic Surgery , Society of Thoracic Surgeons , American Association for Thoracic Surgery , International Society for Mechanical Circulatory Support , International Society of Heart and Lung Transplantation , JAPANESE ASSOCIATION FOR CORONARY ARTERY SURGERY , JAPANESE HEART FAILURE SOCIETY , Japanese Association for Computer Assisted Surgery , The Asian Society for Cardiovascular and Thoracic Surgery , The transplantation Society , 日本組織移植学会 , 日本移植学会 , 日本内視鏡外科学会 , 日本人工臓器学会 , 日本心臓病学会 , 日本循環器学会 , 日本心臓血管外科学会 , 日本胸部外科学会 , 日本外科学会

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