Iwawaki Takao

イワワキタカオ | Iwawaki Takao

Affiliation and department：
Job title： Professor
Homepage URL (2)： https://www.kanazawa-med.ac.jp/laboratories/mri-cell-medicine.html , https://www.kanazawa-med.ac.jp/laboratories/en/mri-cell-medicine.html

Research field (6)： Cell biology , Molecular biology , Medical biochemistry , Nutrition and health science , Physiology , Laboratory animal science

Research keywords (9)： Cellular Stress Response , in vivo Imaging , Metabolic Disease , Proteostasis , Fatigue , Aging , Sleep , Inflammation , Food Intake Regulation

Research theme for competitive and other funds (11)：

2023 - 2025 Development of model mice to visualize mitochondrial stress.
2021 - 2024 Molecular mechanisms of fatigue approached by studies of cellular stress and inflammation
2018 - 2021 Transgenic mice for imaging of cellular stress associated with diseases and aging
2015 - 2017 Molecular mechanism of overeating regulated by cellular stress response
2012 - 2015 Physiological and pathological function of cellular stress responses

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Papers (126)：

Chiharuko Ushimoto, Shigeru Sugiki, Kenshirou Kunii, Shinya Inoue, Eriko Kuroda, Ryoko Akai, Takao Iwawaki, Katsuhito Miyazawa. Dynamic change and preventive role of stress response via Keap1-Nrf2 during renal crystal formation. Free radical biology & medicine. 2023. 207. 120-132
Deepika Awasthi, Sahil Chopra, Byuri A Cho, Alexander Emmanuelli, Tito A Sandoval, Sung-Min Hwang, Chang-Suk Chae, Camilla Salvagno, Chen Tan, Liliana Vasquez-Urbina, et al. Inflammatory ER stress responses dictate the immunopathogenic progression of systemic candidiasis. The Journal of clinical investigation. 2023. 133. 17
Yuta Inoue, Akihiko Uchiyama, Syahla Nisaa Amalia, Mai Ishikawa, Keiji Kosaka, Akiko Sekiguchi, Sachiko Ogino, Yoko Yokoyama, Ryoko Torii, Mari Hosoi, et al. Keratinocyte-Specific SOX2 Overexpression Suppressed Pressure Ulcer Formation after Cutaneous Ischemia-Reperfusion Injury via Enhancement of Amphiregulin Production. The Journal of investigative dermatology. 2023
Bernardita Medel, José Ignacio Bernales, Alonso Lira, Dominique Fernández, Takao Iwawaki, Pablo Vargas, Fabiola Osorio. The Unfolded Protein Response Sensor IRE1 Regulates Activation of In Vitro Differentiated Type 1 Conventional DCs with Viral Stimuli. International journal of molecular sciences. 2023. 24. 12
Dawiyat Massoudi, Seán Gorman, Yien-Ming Kuo, Takao Iwawaki, Scott A Oakes, Feroz R Papa, Douglas B Gould. Deletion of the Unfolded Protein Response Transducer IRE1α Is Detrimental to Aging Photoreceptors and to ER Stress-Mediated Retinal Degeneration. Investigative ophthalmology & visual science. 2023. 64. 4. 30-30

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Patents (4)：

Inflammation reporter system
An oxidative stress indicator for expressing the nucleic acid construct
Two dimensional inspection system of endoplasmic reticulum stress
Method for expression of protein using frameshift of mRNA in the presence of biostimulation

Education (3)：

1997 - 2001 Nara Institute of Science and Technology Graduate School of Biological Sciences Doctoral Course
1995 - 1997 Nara Institute of Science and Technology Graduate School of Biological Sciences Master Course
1991 - 1995 Nara University of Education Undergraduate of Education High School Teacher-Training Course (Biology / Science)

Professional career (1)：

PhD (NAIST)

Work history (9)：

2023/10 - 現在 Kanazawa Medical University Hospital Sleep Medicine Center
2016/04 - 現在 Kanazawa Medical University Division of Cell Medicine, Department of Life Science, Medical Research Institute Professor
2015/04 - 2016/03 Gunma University Education and Research Support Center, Graduate School of Medicine Associated Professor (Lab Head)
2011/02 - 2015/03 Gunma University Advanced Scientific Research Leaders Development Unit Associated Professor (Lab Head)
2007/10 - 2011/03 Japan Science and Technology Agency Project of Metabolism and Celluar Function PRESTO Researcher

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Association Membership(s) (5)：

JAPANESE ASSOCIATION FOR LABORATORY ANIMAL SCIENCE , Japanese Society of Fatigue Science , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , The Biomedical Society for Stress Response Japan , JAPAN SOCIETY FOR CELL BIOLOGY

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