Rchr
J-GLOBAL ID：200901020394019134   Update date: Aug. 17, 2024

Ihara Yoshito

イハラ ヨシト | Ihara Yoshito
Affiliation and department：
Wakayama Medical University Department of Biochemistry

About Wakayama Medical University Department of Biochemistry


Job title： Professor
Research field  (4)： Pathobiochemistry ,  Medical biochemistry ,  Functional biochemistry ,  Structural biochemistry
Research keywords  (6)： ストレス応答 ,  糖鎖生物学 ,  分子シャペロン ,  Stress response ,  Glycobiology ,  Molecular chaperone
Research theme for competitive and other funds  (30)：
  • 2022 - 2025 p53アミロイドーシスとしてのp53遺伝子変異卵巣癌の病態メカニズムの解明
  • 2021 - 2024 Investigation of the pathophysiological functions of C-mannosyl tryptophan in ovarian cancer
  • 2021 - 2024 胎盤形成不全における小胞体シャペロンーカルネキシンの発現と病態意義の解明
  • 2019 - 2023 小胞体ストレスによる分子シャペロンの局在変化が胎盤形成不全に与える影響
  • 2016 - 2021 Chemical Biology of ER related glycan modifications
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Papers (105)：
  • Shotaro Tabata, Yusuke Yamashita, Yoko Inai, Shuhei Morita, Hideki Kosako, Tomoyuki Takagi, Kotaro Shide, Shino Manabe, Taka-Aki Matsuoka, Kazuya Shimoda, et al. C-Mannosyl tryptophan is a novel biomarker for thrombocytosis of myeloproliferative neoplasms. Scientific reports. 2024. 14. 1. 18858-18858
  • Kazuchika Nishitsuji, Remi Mito, Midori Ikezaki, Hiromu Yano, Yukio Fujiwara, Eri Matsubara, Taro Nishikawa, Yoshito Ihara, Kenji Uchimura, Naoyuki Iwahashi, et al. Impacts of cytoplasmic p53 aggregates on the prognosis and the transcriptome in lung squamous cell carcinoma. Cancer science. 2024
  • 井内 陽子, 南方 志帆, 眞鍋 史乃, 岩橋 尚幸, 井箟 一彦, 井原 義人. 卵巣癌腹膜播種モデルにおける腫瘍形成と腹腔内細胞のC-マンノシル化トリプトファン産生. 和歌山医学. 2024. 75. 1. 76-76
  • Yoshiko Takeda-Uchimura, Midori Ikezaki, Tomoya O Akama, Yoshito Ihara, Fabrice Allain, Kazuchika Nishitsuji, Kenji Uchimura. GlcNAc6ST2/CHST4 Is Essential for the Synthesis of R-10G-Reactive Keratan Sulfate/Sulfated N-Acetyllactosamine Oligosaccharides in Mouse Pleural Mesothelium. Molecules (Basel, Switzerland). 2024. 29. 4
  • 西辻 和親, 御任 玲美, 池崎 みどり, 藤原 章雄, 岩橋 尚幸, 井原 義人, 内村 健治, 菰原 義弘. p53変異癌における細胞内p53凝集体の予後への影響(Correlation of the presence of cytoplasmic p53 aggregates with poor prognosis in p53-mutated cancers). 日本病理学会会誌. 2024. 113. 1. 341-341
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MISC (68)：
  • 西辻和親, 池崎みどり, 藤本正数, 岩橋尚幸, 内村健治, 井原義人. Analysis of the CL40-reactive sialylated glycans in ovarian cancer associated with lipid droplet accumulation. 日本糖質学会年会要旨集. 2023. 42nd
  • 井原義人, 井内陽子, 岩橋尚幸, 南方志帆, 南方志帆, 森乃絢, 池崎みどり, 西辻和親, 井箟一彦, 眞鍋史乃. Pathophysiological response of protein C-mannosylation in ovarian cancer. 日本糖質学会年会要旨集. 2023. 42nd
  • 西辻和親, 池崎みどり, 眞鍋史乃, 眞鍋史乃, 井原義人. Functions of Protein C-Mannosylation in Physiology and Pathology. Trends in Glycoscience and Glycotechnology (Web). 2023. 35. 204
  • 西辻和親, 池崎みどり, 内村健治, 内村健治, 岩橋尚幸, 西岡香穂, 藤原章雄, 菰原義弘, 井箟一彦, 井原義人. Sulfated glycosaminoglycan-mediated spreading of p53 amyloid and its contribution to cancer pathology. 日本糖質学会年会要旨集. 2022. 41st
  • 南方志帆, 井内陽子, 西辻和親, 眞鍋史乃, 眞鍋史乃, 井原義人. Investigating the cellular uptake mechanism of C-mannosyl tryptophan. 日本糖質学会年会要旨集. 2022. 41st
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Education (4)：
  • - 1994 Osaka University
  • - 1994 Osaka University Graduate School, Division of Medicine
  • - 1990 The University of Tokushima Faculty of Medicine School of Medicine
  • - 1990 The University of Tokushima Faculty of Medicine School of Medicine
Professional career (1)：
  • Ph.D. (Osaka University)
Work history (10)：
  • 2002 - 2007 Nagasaki University School of Medicine
  • 2002 - 2007 Nagasaki University School of Medicine, Associate professor
  • 2007 - - 和歌山県立医科大学医学部 教授
  • 2007 - - Wakayama Medical University, Professor
  • 1998 - 2002 Nagasaki University School of Medicine
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Committee career (2)：
  • 日本糖質学会 評議員
  • 日本生化学会 評議員
Awards (2)：
  • 1993 - 日本生化学会JB論文賞(第1回)
  • 1993 - JB Award (The Japanese Biochemical Society)
Association Membership(s) (8)：
日本糖質学会 ,  米国細胞生物学会(The American society for cell biology) ,  日本癌学会 ,  日本生化学会 ,  The Japanese Society of Carbohydrate Research ,  The American Society for Cell Biology ,  The Japanese Cancer Association ,  The Japanese Biochemical Society
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