Research theme for competitive and other funds (8)：
2021 - 2024 Renal vascular dysfunction and acute glomerulonephritis by haemolytic exotoxin fromStreptococcus pyogenes
2016 - 2018 プロテインホスファターゼ2Aによる平滑筋化学-力学変換調節のメカニズム
2015 - 2016 高感度Phos-tag法を応用した毛様体筋の収縮調節機序の解析
2016 - 毛様体筋のミオシンリン酸化非依存性収縮調節機構の解明
2012 - 2014 ムスカリン受容体作動性陽イオンチャネルとその調節系の分子実体解明
2012 - 2014 超高感度リン酸化定量法の開発:単離平滑筋細胞の生化学的解析を目指して
2010 - 2011 微小平滑筋におけるシグナル伝達の高感度定量解析法の開発
2008 - 2010 Mechanisms regulating vasoconstriction in the kidney
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Papers (25)：
Yoshinori Tanaka, Lina Kozuma, Hirotsugu Hino, Kosuke Takeya, Masumi Eto. Abemaciclib and Vacuolin-1 decrease aggregate-prone TDP-43 accumulation by accelerating autophagic flux. Biochemistry and Biophysics Reports. 2024. 38. 101705-101705
Hiroko Ikeda, Eikichi Ihara, Kosuke Takeya, Koji Mukai, Manabu Onimaru, Kenoki Ouchida, Yoshitaka Hata, Xiaopeng Bai, Yoshimasa Tanaka, Taisuke Sasaki, et al. The interplay between alterations in esophageal microbiota associated with Th17 immune response and impaired LC20 phosphorylation in achalasia. Journal of gastroenterology. 2024
Jason A. Kirkbride, Garbo Young Nilsson, Jee In Kim, Kosuke Takeya, Yoshinori Tanaka, Hiroshi Tokumitsu, Futoshi Suizu, Masumi Eto. PHI-1, an Endogenous Inhibitor Protein for Protein Phosphatase-1 and a Pan-Cancer Marker, Regulates Raf-1 Proteostasis. Biomolecules. 2023. 13. 12. 1741-1741
Yoshinori Tanaka, Shun-ichi Ito, Yuki Honma, Masato Hasegawa, Fuyuki Kametani, Genjiro Suzuki, Lina Kozuma, Kosuke Takeya, Masumi Eto. Dysregulation of the Progranulin-driven Autophagy-lysosomal Pathway Mediates Secretion of the Nuclear Protein TDP-43. Journal of Biological Chemistry. 2023. 105272-105272
Kosuke TAKEYA. Renal blood flow and glomerular filtration rate : aging and humoral factors. Kidney and dialysis. 2022. 93. 5. 675-679
Comparison of Smooth Muscle Regulatory Protein CPI-17 Expression in Rat Renal Arterioles.
(The 101st Annual Meeting of The Physiological Society of Japan 2024)
Relaxing effects of rubratoxin A on smooth muscles by inhibiting PP2A
(第97回日本生理学会大会 2020)
2002 - 2005 Hokkaido University Graduate School of Science Department of Chemistry
- 2005 Hokkaido University Graduate School, Division of Natural Science Division of Chemistry
2000 - 2002 北海道大学大学院 理学研究科 化学専攻 修士課程
2000 - 2002 Hokkaido University Graduate School of Science Department of Chemistry
1996 - 2000 Hokkaido University Faculty of Science Department of Chemistry
- 2000 Hokkaido University Faculty of Science Chemistry
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Professional career (1)：
博士(理学) (北海道大学)
Work history (5)：
2018/04 - 現在 Okayama University of Science Faculty of Veterinary Medicine Senior Lecturer
2010/04 - 2018/03 Asahikawa Medical University Department of Physiology Assistant Professor
2005/11 - 2010/03 カルガリー大学 博士研究員
2005/11 - 2010/03 University of Calgary Smooth Muscle Research Group Postdoctral Fellow
2005 - - Postdoc. Faculty of Medicine, University of Calgary
Committee career (5)：
2016/03 - 現在 日本生理学会 評議員
2015/08 - 現在 日本平滑筋学会 広報委員
2014/08 - 現在 日本平滑筋学会 評議員
2017/08 - 2021/08 日本平滑筋学会 若手の会 会長
2012/08 - 2017/08 日本平滑筋学会 若手の会 事務局長
Awards (6)：
2023/08 - Excellent Article Prize 2022 Possible roles of N- and C-terminal unstructured tails of CPI-17 in regulating Ca2+ sensitization force of smooth muscle
2020/08 - Japan Society of Smooth Muscle Research Excellent Article Prize 2019
2016/08 - Japan Society of Smooth Muscle Research Excellent Article Prize 2015 Force-inhibiting effect of Ser/Thr protein phosphatase 2A inhibitors on bovine ciliary muscle.
2015/08 - 日本平滑筋学会 第1回白白鳥常男賞
2013/03 - 日本生理学会 佐川喜一賞
2008 - Pfizer/Libin Postdoc Prize
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Association Membership(s) (6)：
JAPAN SOCIETY OF SMOOTH MUSCLE RESEARCH
, 日本生理学会
, 日本生物物理学会
, 日本生化学会
, The Biophysical Society of Japan
, The Japanese Biochemical Society
