kondo kazunao

コンドウカズナオ | kondo kazunao

Affiliation and department：

Research field (1)： Pharmacology

Research keywords (2)： clinical pharmacology , platelet aggregation

Research theme for competitive and other funds (7)：

2016 - 2019 Tetrahydrobiopterin-deficiency causes hypertension with fluctuation, bradycardia and priapism.
2013 - 2016 Study on the disease induced by imbalance of tetrahydrobiopterin-metabolism and research on the mechanisms for protection against the state.
2010 - 2012 Development of tetrahydrobiopterin-based therapy for neurological and cardiovascular disease
2004 - 2005 Origin of neointima cells and mechanism of intima thickening formation, using radiation chimera rat.
2002 - 2003 Role of osteopontin in diabetic atherosclerosi

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Papers (58)：

狩野泰輝, 管沼由唯, 池本和久, 一瀬千穂, 望月利昭, 近藤一直. 鎮静薬デクスメデトミジンが血小板凝集に与える影響. 日本血栓止血学会誌. 2023. 34. 2. 276-276
Yui Suganuma, Chiho Sumi-Ichinose, Taiki Kano, Kazuhisa Ikemoto, Taei Matsui, Hiroshi Ichinose, Kazunao Kondo. Quinonoid dihydropteridine reductase, a tetrahydrobiopterin-recycling enzyme, contributes to 5-hydroxytryptamine-associated platelet aggregation in mice. Journal of Pharmacological Sciences. 2022. 150. 173-179
Katsuya Miyajima, Yusuke Sudo, Sho Sanechika, Yoshitaka Hara, Mieko Horiguchi, Feng Xu, Minori Suzuki, Satoshi Hara, Koichi Tanda, Ken-Ichi Inoue, et al. Perturbation of monoamine metabolism and enhanced fear responses in mice defective in the regeneration of tetrahydrobiopterin. Journal of neurochemistry. 2022. 161. 2. 129-145
Chiho Sumi-Ichinose, Yui Suganuma, Taiki Kano, Kazuhisa Ikemoto, Noriko Ihira, Hiroshi Ichinose, Kazunao Kondo. Priapism caused by partial deficiency of tetrahydrobiopterin through hypofunction of the sympathetic neurons in sepiapterin reductase gene-disrupted mice. Journal of Inherited Metabolic Disease. 2022. 45. 3. 621-634
Kazuhisa Ikemoto, Chiho Sumi-Ichinose, Yui Suganuma, Taiki Kano, Noriko Ihira, Toshiharu Nagatsu, Kazunao Kondo. Salivary neopterin and related pterins: their comparison to those in plasma and changes in individuals. The Journal of Biochemistry. 2021. 170. 4. 559-567

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MISC (32)：

中島昭, 近藤一直, 宮地栄一, 飯塚成志, 池本和久, 石原悟, 大熊真人, 金子葉子, 河合房夫, 小谷侑, et al. 意見プレゼンテーション評価シートの導入による学生発表会の改善. 医学教育. 2017. 48. 5. 323-325
Y. Suganuma, T. Kano, K. Ikemoto, C. Ichinose, T. Nomura, K. Kondo. Orally administered tetrahydrobiopterin (BH4) suppresses platelet aggregation via intraplatelet production of nitric oxide. JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2015. 13. 908-909
Yui Suganuma, Taiki Kano, Kazuhisa Ikemoto, Chiho Ichinose, Takahide Nomura, Kazunao Kondo. Antiplatelet effect of tetrahydrobiopterin in mouse whole blood aggregation and its NO-independent mechanism. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 132P-132P
一瀬宏, 本間大悟, 一瀬鷲見千穂, 近藤一直. モノアミン・ビオプテリン代謝改変マウスを用いたモノアミンニューロンの制御機構と発達変化の解析. 自律神経 = The Autonomic nervous system. 2013. 50. 1. 16-17
Yui Suganuma, Kazuhisa Ikemoto, Chiho Ichinose, Takahide Nomura, Kazunao Kondo. Anti-platelet effect of tetrahydrobiopterin on mouse whole blood. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2013. 121. 85P-85P

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Lectures and oral presentations (23)：

ジヒドロプテリジン還元酵素欠損マウスにおけるフェニルアラニン及び葉酸代謝異常
(第27回日本プテリジン研究会 2013)
マウス血小板凝集に対するテトラヒドロビオプテリンの作用
(第27回日本プテリジン研究会 2013)
低酸素環境がヒト臍帯静脈内皮細胞(HUVEC)に及ぼす影響
(第45回藤田学園医学会 2013)
テトラヒドロビオプテリンの抗血小板作用におけるNOの関与
(第123回日本薬理学会近畿部会 2013)
Disturbance in the biosynthesis of monoamines and PTSD-like anxiety phenotype in the dihydropteridine reductase-deficient mice
(第35回日本神経科学大会 2012)

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Professional career (1)：

Work history (4)：

2007/09 - 現在 Fujita Health University Department of Pharmacology Professor
1999/10 - 2007/08 Hamamatsu University School of Medicine Department of Pharmacology Associate Professor
1994/09 - 1999/09 Hamamatsu University School of Medicine Department of Pharmacology Assistant Professor
1990/06 - 1992/03 Kakegawa Municipal Hospital Internal Medicine Doctor

Association Membership(s) (3)：

日本血栓止血学会 , 日本薬理学会 , 日本臨床薬理学会

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