Watanabe Shiro

ワタナベシロウ | Watanabe Shiro

Affiliation and department：

Research field (3)： Internal medicine - General , Environmental and pharmaceutical development resources , Pharmaceuticals - health and biochemistry

Research keywords (11)： essential fatty acid , inflammatory bowel disease , gut flora , bile acid , 摂食行動 , サイトカイン , LPS , オウゴン , 漢方薬 , 小腸傷害 , NSAID

Research theme for competitive and other funds (15)：

2018 - 2021 Experimental assessment of preventive effects of kampo medicines against metabolic syndromes through the modification of intestinal bile acid metabolism
2015 - 2018 Evaluation of protective effect of dietary supplementation with n-3 fatty acids against feeding disorder following cerebral ischemia in mice
2014 - 2018 Molecular mechanism of luminal pressure reception and ATP release in gastrointestinal epithelium
2014 - 2017 Role of pregnane X receptor in the preventive effect of Boiogito against experimentally induced cholestatic liver injury
2011 - 2013 Detection of novel actions of kampo medicines for lipid metabolism by lipidomic analysis

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Papers (122)：

Shun Takano, Koudai Kani, Kaichi Kasai, Naoya Igarashi, Miyuna Kato, Kana Goto, Yudai Matsuura, Mayuko Ichimura-Shimizu, Shiro Watanabe, Koichi Tsuneyama, et al. Antibiotic effects on gut microbiota modulate diet-induced metabolic dysfunction-associated steatohepatitis development in C57BL/6 mice. Genes to cells : devoted to molecular & cellular mechanisms. 2024
Naoya Igarashi, Kaichi Kasai, Yuki Tada, Koudai Kani, Miyuna Kato, Shun Takano, Kana Goto, Yudai Matsuura, Mayuko Ichimura-Shimizu, Shiro Watanabe, et al. Impacts of liver macrophages, gut microbiota, and bile acid metabolism on the differences in iHFC diet-induced MASH progression between TSNO and TSOD mice. Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 2024
Shiro Watanabe, Kyoka Takahashi, Suresh Awale, Yukihiro Furusawa, Yoshiaki Tabuchi, Yuto Nishidono, Ken Tanaka. Goreisan-induced modulation of fecal bile acid composition and gut microbiota in mice. Traditional & Kampo Medicine. 2024
Masaru Doshi, Yujin Natori, Akira Ishii, Daisuke Saigusa, Shiro Watanabe, Makoto Hosoyamada, Yutaka Hirashima-Akae. Hypothermia increases adenosine monophosphate and xanthosine monophosphate levels in the mouse hippocampus, preventing their reduction by global cerebral ischemia. Scientific reports. 2024. 14. 1. 3187-3187
Yoshiyuki Watanabe, Shiho Fujisaka, Yoshitomo Morinaga, Shiro Watanabe, Allah Nawaz, Hideki Hatta, Tomonobu Kado, Ayumi Nishimura, Muhammad Bilal, Muhammad Rahil Aslam, et al. Isoxanthohumol improves obesity and glucose metabolism via inhibiting intestinal lipid absorption with a bloom of Akkermansia muciniphila in mice. Molecular metabolism. 2023. 101797-101797

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MISC (27)：

道志勝, 名取雄人, 石井晃, 三枝大輔, 渡辺志朗, 細山田真, 赤江豊. Effect of hypothermia on the changes in the levels of metabolites in the mouse hippocampus caused by cerebral ischemia. 日本薬学会年会要旨集(Web). 2024. 144th
道志勝, 名取雄人, 石井晃, 渡辺志朗, 細山田真, 赤江豊. Metabolome analysis of hippocampus and serum in mouse model of cerebral ischmeia. 日本薬学会年会要旨集(Web). 2023. 143rd
守田雅志, 浅倉礼奈, 土手陽世, 山田祥大朗, 渡辺志朗, 川口甲介, 宗孝紀. Involvement of peroxisomal membrane protein ABCD1 in lipid droplet formation. 日本薬学会年会要旨集(Web). 2022. 142nd
道志勝, 渡辺志朗, 名取雄人, 細山田真, 赤江豊. Triiodothyronine aggravates delayed neuronal death caused by transient cerebral ischemia in mice. 日本薬学会年会要旨集(Web). 2021. 141st
道志勝, 渡辺志朗, 名取雄人, 細山田真, 赤江豊. Effect of thyroid hormone on occurrence of neuronal death following cerebral ischemia-reperfusion in mice. 日本薬学会年会要旨集(CD-ROM). 2020. 140th

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Education (2)：

1988 - 1991 Graduate School of Nagoya City University
1986 - 1988 Graduate School of Nagoya City University

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