Sakamoto Kenji

サカモトケンジ | Sakamoto Kenji

Affiliation and department：
Job title： Professor

Research field (2)： Pharmacology , Pharmaceuticals - health and biochemistry

Research keywords (2)：薬理学 , Pharmacology

Research theme for competitive and other funds (12)：

2021 - 2024 炎症性反応の空間的・時間的制御による新規網膜変性疾患治療戦略の確立
2018 - 2021 Basic research for construction of the therapies for retinal degenerative diseases by profiling microRNAs
2015 - 2018 Significance of the change in the expression levels of microRNAs in neurodegenerative diseases in the retina
2012 - 2015 Role of minor iron element for developing retinal degeneration
2009 - 2011 Analysis of the mechanism of photoreceptor cell death induced by retinitis pigmentosa in order to develop the new therapy.

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Papers (251)：

Rina Yagasaki, Akane Morita, Asami Mori, Kenji Sakamoto, Tsutomu Nakahara. The Anti-Diabetic Drug Metformin Suppresses Pathological Retinal Angiogenesis via Blocking the mTORC1 Signaling Pathway in Mice (Metformin Suppresses Pathological Angiogenesis). Current eye research. 2024. 49. 5. 505-512
Erika Kamiya, Akane Morita, Asami Mori, Kenji Sakamoto, Tsutomu Nakahara. The process of methylglyoxal-induced retinal capillary endothelial cell degeneration in rats. Microvascular research. 2023. 146. 104455-104455
Asami Mori, Yuna Ezawa, Daiki Asano, Toshiki Kanamori, Akane Morita, Toshihide Kashihara, Kenji Sakamoto, Tsutomu Nakahara. Resveratrol dilates arterioles and protects against N-methyl-d-aspartic acid-induced excitotoxicity in the rat retina. Neuroscience letters. 2023. 793. 136999-136999
Asami Mori, Haruka Seki, Satoru Mizukoshi, Takashi Uezono, Kenji Sakamoto. Role of Prostaglandins in Nitric Oxide-Induced Glial Cell-Mediated Vasodilation in Rat Retina. Biomolecules. 2022. 12. 10. 1403-1403
森田茜, 菅原志央吏, 入田孟大, 柏原俊英, 森麻美, 坂本謙司, 中原努. VEGF受容体阻害薬を用いた新生仔マウス新規網膜異常血管新生モデル. 眼薬理. 2022. 36. 1. 76-78

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MISC (13)：

森田茜, 矢ヶ崎莉菜, 森麻美, 森麻美, 坂本謙司, 坂本謙司, 柏原俊英, 中原努. マウスにおけるmetforminの病的細胞血管新生に対する抑制効果. 日本薬理学雑誌. 2023. 158. Supplement
森田茜, 宮永香純, 浅野大樹, 森麻美, 森麻美, 坂本謙司, 坂本謙司, 中原努. 新生仔マウスにおけるVEGF受容体下流シグナル分子活性の可視化. 日本眼薬理学会プログラム・講演抄録集. 2021. 40th
森田茜, 宮永香純, 浅野大樹, 有馬志保, 森麻美, 森麻美, 坂本謙司, 坂本謙司, 長光亨, 中原努. The Visualization of ERK Activity at the Vascular Front in the Neonatal Mouse Retina. 眼薬理. 2021. 35. 1
森麻美, 中野歩希, 浅野大樹, 森田茜, 坂本謙司, 坂本謙司, 中原努. 未熟児網膜症モデルラットにおいて網膜血管内皮依存性拡張反応が減弱する. 生体機能と創薬シンポジウム要旨集. 2019. 2019
森麻美, 矢野恵理佳, 浅野大樹, 森田茜, 坂本謙司, 坂本謙司, 中原努. ラット網膜におけるグリア-血管連関:BK_Caチャネルの関与. 日本薬学会関東支部大会講演要旨集. 2019. 63rd

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Books (1)：

Education (5)：

Professional career (3)：

Work history (7)：

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Committee career (1)：

Awards (1)：

Association Membership(s) (5)：

日本眼薬理学会 , The Association for Research in Vision and Ophthalmology , Society of Neurosciences , 日本薬学会 , 日本薬理学会

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