Hideyuki Saya

サヤヒデユキ | Hideyuki Saya

Affiliation and department：
Job title： Professor
Other affiliations (1)：

Keio University Professor

Research field (1)： Tumor biology

Research theme for competitive and other funds (4)：

2021 - 2023 メチオニン代謝を基盤としたがん治療抵抗性機構の解明と新規治療標的の同定
2020 - 2023 がん関連線維芽細胞誘導分子機構の解明とその阻害に基づく腫瘍微小環境制御
2019 - 2021 癌細胞シグナル活性化因子14-3-3ζを標的とした新規膵臓癌治療薬の開発
2017 - 2020 Elucidation of underlyingmechanism of MKL1-mediated induction of cancer associated fibroblasts and its clinical applications

Papers (447)：

Takatsune Shimizu, Kiyomi Kimura, Eiji Sugihara, Sayaka Yamaguchi-Iwai, Hiroyuki Nobusue, Oltea Sampetrean, Yuji Otsuki, Yumi Fukuchi, Kaori Saitoh, Keiko Kato, et al. MEK inhibition preferentially suppresses anchorage-independent growth in osteosarcoma cells and decreases tumors in vivo. Journal of Orthopaedic Research. 2021
Ikue Tai-Nagara, Yukiko Hasumi, Dai Kusumoto, Hisashi Hasumi, Keisuke Okabe, Tomofumi Ando, Fumio Matsuzaki, Fumiko Itoh, Hideyuki Saya, Chang Liu, et al. Blood and lymphatic systems are segregated by the FLCN tumor suppressor. Nature Communications. 2020. 11. 1
Tanno N, Kuninaka S, Fujimura S, Takemoto K, Okamura K, Takeda N, Araki K, Araki M, Saya H, Ishiguro K.i. Phosphorylation of the Anaphase Promoting Complex activator FZR1/CDH1 is required for Meiosis II entry in mouse male germ cell. Scientific Reports. 2020. 10. 1. 10094-10094
Shono K, Yamaguchi I, Mizobuchi Y, Kagusa H, Sumi A, Fujihara T, Nakajima K, Kitazato K.T, Matsuzaki K, Saya H, et al. Downregulation of the CCL2/CCR2 and CXCL10/CXCR3 axes contributes to antitumor effects in a mouse model of malignant glioma. Scientific Reports. 2020. 10. 1
Koike N, Kota R, Naito Y, Hayakawa N, Matsuura T, Hishiki T, Onishi N, Fukada J, Suematsu M, Shigematsu N, et al. 2-Nitroimidazoles induce mitochondrial stress and ferroptosis in glioma stem cells residing in a hypoxic niche. Communications Biology. 2020. 3. 1

ｍore...

MISC (80)：

今枝慶蓉, 増田健太, 永井晋平, 田村友宏, 杉原英志, 山崎淳太郎, 大槻雄士, 信末博行, 千代田達幸, 小林佑介, et al. 新規マウスモデルを用いた高異型度漿液性癌の予後不良に関連するバイオマーカーの同定(Identification of biomarkers associated to poor prognosis in high-grade serous carcinoma using novel mouse models). 日本癌学会総会記事. 2023. 82回. 1044-1044
大場茂生, 杉原英志, 山田勢至, 中江俊介, 西山悠也, 武藤淳, 安達一英, 安部雅人, 佐谷秀行, 廣瀬雄一. がんゲノム診断がん遺伝子パネル検査を用いた髄膜腫の解析. Brain Tumor Pathology. 2023. 40. Suppl. 061-061
佐谷秀行, 杉原英志. 【泌尿器科医必見!がんゲノム医療の基本と応用】本邦におけるがん遺伝子パネル検査の現状. 泌尿器外科. 2023. 36. 3. 197-200
糠谷拓尚, 住友誠, 竹田真由, 杉原英志, 佐谷秀行, 白木良一. 前立腺がん-リスク別・進行期別治療のトピックス- 前立腺癌のBRCA遺伝子のloss of heterozygosityの頻度とその意義. 日本癌治療学会学術集会抄録集. 2022. 60回. OWS18-6
住友誠, 竹田真由, 野原祥夫, 谷嶋成樹, 山田勢至, 塚本徹哉, 杉原英志, 西原広史, 佐谷秀行. In-house包括的シーケンスシステムを用いた治療初期がん組織のゲノムプロファイリングの臨床的意義(Clinical impact of a cancer genomic profiling test in treatment-naieve cancer tissues using an in-house comprehensive targeted sequencing system). 日本癌学会総会記事. 2022. 81回. LBP-14

ｍore...

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page